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Doctor insights on: Can You Have Both The Thalassemia Trait And Sickle Cell Trait

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Can you have both the thalassemia trait and sickle cell trait?

Can you have both the thalassemia trait and sickle cell trait?

Yes and no: If you have the sickle cell mutation on one beta hemoglobin gene and a thalassemia mutation on the second gene, then you have sickle cell beta thalassemia - this is not a trait but a disease. The severity of the disease is dependent upon the size/ location of the thalassemia mutation. ...Read more

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Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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If I have sickle cell trait is it possible to now be sickle cell anemia?

If I have sickle cell trait is it possible to now be sickle cell anemia?

Confusing question: SS disease requires the genes for sickle cell from both parents, while S trait has it from one. You cannot change the genetic makeup that you were born with. Someone with trait can have a kid with SS if the partner has trait or SS. ...Read more

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If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait . With our technology now, nothing can alter the risk. Sorry to say , the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more

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If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

No: There are varying forms of sickling diseases, however it is a recessive trait and so the parents may appear fine but carry the trait and yet have a child with the disease. ...Read more

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Do both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Do both parents have to have the sickle cell trait for the child to have sickle cell anemia?

No: 2 abnormal (sickle cell) gene have to be inherited to have sickle cell disease. This can happen if both patents have sickle cell trait, one parent has sickle cell disease or both have sickle cell disease. ...Read more

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Could both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Could both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Yes: Sickle cell anemia requires the gene from both parents to cause ss anemia. If only one parent gave the gene, the kid would be a trait carrier. ...Read more

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Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?

Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?

NO: To simplify- providing that the father has a completely normal blood - ( no other type of congenital/hereditary bood disorder-like thalasemia minor, hemoglobin c disease etc) - the baby will have 50% risk to have sickle cell trait-but the baby will not have sickle cell anemia. ...Read more

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Please help! what happens if you have both hemaglobin c trait and sickle cell trait?

Less severe than SS: Hemoglobin sc disease is the second most common type of sickle cell disease. It occurs when you inherit the hb c gene from one parent and the hb s gene from the other. Individuals with hb sc have similar symptoms to individuals with hb ss (sickle cell disease). However, the anemia is less severe. ...Read more

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Is there a treatment available for people with sickle cell trait and alpha thalassemia?

Yes: Hematologists (blood specialists) evaluate persons with both sickle cell trait and Alpha thalassemia disease. The sickling should not be a problem, because the person is only sickle trait, and Alpha thal. Mutations seem to lessen the tendency of blood cells to sickle from the sickle cell mutation. Persons with both sickle trait and Alpha thal. Trait probably won't have symptoms needing treatment. ...Read more

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Dr. Scott Keith
73 doctors shared insights

Sickle Cell Carrier (Definition)

Sickle cell trait is a genetic condition where a person has one gene copy for the abnormal hemoglobin protein. Having two gene copies would cause red blood cells ...Read more


Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more