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Doctor insights on: Can You Get Serotonin Syndrome From Smoking Pot

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Can taking wellbutrin (bupropion) and Zoloft and smoking cannabis cause serotonin syndrome? I've had a few panic attacks that I am worried may actually be ss

Can taking wellbutrin (bupropion) and Zoloft and smoking cannabis cause serotonin syndrome?  I've had a few panic attacks that I am worried may actually be ss

Cannabis & serotonin: Cannabis can increase serotonin levels, and definitely should not be used with ssri's like zoloft (sertraline). In fact if you've been struggling with depression and/or anxiety, using any additional drugs is a really bad idea. ...Read more

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Dr. Zahid Niazi
163 doctors shared insights

Serotonin Syndrome (Definition)

Complex as can be grouped with neuroleptic malignant syndrome. Characterized by hyperthermia, muscle rigidity, altered mental status, usually associated with medicines that block or deplete dopamine, such as most anti-psychotics, and ssri antidepressants. May be precipitated by fever, infection, high environmental temperatures. Can be life ...Read more


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Can you get serotonin syndrome from long term Zoloft (sertraline) use?

Can you get serotonin syndrome from long term Zoloft (sertraline) use?

Combo or high dose: Serotonin syndrome is too much serotonin in the brain. If you have tolerated zoloft (sertraline) for a long time, than your chances of developing the syndrome are low, unless your dose was increased or another med added. Other psychotropics, pain meds (e.g. Ultram), migraine meds (triptans), HIV meds, stimulants & hallucinogens w/ zoloft (sertraline) can raise the risk. Inform your doctor of all the meds you're taking. ...Read more

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Can you get serotonin syndrome with a 6,000 mg of sertraline combined with 400 mg of phenergan (promethazine) what can happen.

Can you get serotonin syndrome with a 6,000 mg of sertraline combined with 400 mg of phenergan (promethazine) what can happen.

Yes: 6000 mg sertraline is 2 months worth medicine that is more then enough. I hope you are not going to do that again. It will not be fun. Please reach out for help before the pills. ...Read more

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How common is it for somebody to get serotonin syndrome?

How common is it for somebody to get serotonin syndrome?

Uncommon: Serotonin related medications are generally safe as a class, and serotonin syndrome is very uncommon. ...Read more

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Is it possible to get serotonin syndrome from sam-e by itself?

SAM-e: Can cause serotoneric syndrome if taken with Demerol, (meperidine hydrochloride) Talwin, dextromethorphan (Robitussin), Ultram, Triptans or other antidepressants. It should be taken with Folate, B12 and B6 to avoid elevations of serum homocysteine. It is best taken in the morning on an empty stomach to avoid insomnia. It is not regulated by the FDA. Talk to your doctor about dose-some pill forms have a very short half life. ...Read more

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Is it possible to get serotonin syndrome from taking Sam-e by itself?

Sam-e: Sam-e increases a brain chemical called serotonin. I saw no report of serotonin syndrome when it is taken by itself. However, if taken with medications that also increase serotonin, it will. Examples are Tramadol, Demerol , antidepressants, Robitussin Dm (guaifenesin and dextromethorphan) ...Read more

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Is it possible to get serotonin syndrome from taking 400mg of Sam-e by itself, or is it fairly safe?

Is it possible to get serotonin syndrome from taking 400mg of Sam-e by itself, or is it fairly safe?

Probably OK: The Mayo Clinic suggests that higher doses of SAMe can be used (http://www.mayoclinic.org/drugs-supplements/same/dosing/hrb-20059935), but each person is an individual; also, it is important not to be taking other agents that could precipitate serotonin syndrome at the same time. ...Read more

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Can one get serotonin syndrome from using 80 mg of geodon (ziprasidone) everyday?

Can one get serotonin syndrome from using 80 mg of geodon (ziprasidone) everyday?

Possible: Depending on the person, it can happen at any dose. Generally, it is less likely the lower the dose. ...Read more

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Is there any chance to get serotonin syndrome one month after on venlafaxine 75mg without increase the dose ?

Is there any chance to get serotonin syndrome one month after on venlafaxine 75mg without increase the dose ?

If you have any: concerns about side effects, see your MD immediately. This class of meds can produce some very weird and worrisome and potentially dangerous side effects, and sooner than you think. ...Read more

Serotonin (Definition)

Serotonin is a chemical derived from the Amino Acid tryptophan and acts as a neurotransmitter (communicating ...Read more