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Doctor insights on: Can You Get Pregnant While Taking Methotrexate

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How long does it usually take for methotrexate to get out your system and not affect your pregnancy?

How long does it usually take for methotrexate to get out your system and not affect your pregnancy?

Methotrexate: Unless you have been treated for a type of cancer, methotrexate is used to cause a miscarriage or to treat an ectopic pregnancy (pregnancy in tubes). If you were taking it for other than cancer, it is possible that even small doses can adversely affect a pregnancy. See your healthcare provider for advice, and obtain serial ultrasounds to follow the course of the pregnancy. ...Read more

Dr. James Chapman
4 Doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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I took Methotrexate for RA just for 1 month and stopped. Do I still need to wait six months to try to get pregnant even though I used it only 1 month?

I took Methotrexate for RA just for 1 month and stopped. Do I still need to wait six months to try to get pregnant even though I used it only 1 month?

No: Recent research shows 3 months is OK. Consider starting Plaquenil, (hydroxychloroquine) sulfadalazine or both to help control your disease. You should speak with your Rheum about your disease and pregnancy. ...Read more

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Can pregnant women safely take methotrexate?

Can pregnant women safely take methotrexate?

Absolutely not!: METHOTREXATE is an abortofacient! Absolute contraindication. A because of persistent metabolites called MTX polyglutamates, no attempt to get pregnant until three months after using MTX! ...Read more

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Can I go back on duromine 2 weeks after a methotrexate injection for etopic pregnancy?

I think so: I don't think there is a drug interraction, duromine is a weight loss drug. It should not affect the methotrexate; it has likely done its job. That being said make sure the bhcg is going down and consider giving it a few more days out of precaution for the unknown, or use 1/2. There are no absolutes and giving it a couple more days won't hurt. ...Read more

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What to expect after methotrexate shot for ectopic pregnancy?

What to expect after methotrexate shot for ectopic pregnancy?

YOU NEED TO CALL: Your gyn who prescribed that because it is the standard of care for your gyn to tell you what to expect and warning signs to look for and when to call if a problem so please call your gyn now so your gyn who knows you and your situation can go over all of this with you and when u should get the next bhcg drawn to make sure it is going down. ...Read more

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Can I board a 2 hr flight 5 days after methotrexate shot for possible ectopic pregnancy.

Should be ok: As long as where you are has nearby hospitals. Do bring a copy of your medical records, especially blood tests and ultrasound reports. By 5 days after a Methotrexate injection so people notice an increase in pain. However if you are having severe pain and feel lightheaded don't leave town! See your doctor because the ectopic may be bleeding. ...Read more

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My wife has severe RA and takes a high dose of methotrexate weekly. What are the chances of becoming pregnant?

My wife has severe RA and takes a high dose of methotrexate weekly. What are the chances of becoming pregnant?

Does not effect it: Methotrexate does not affect fertility it does however have the potential of causing significant birth defects in a fetus. One should not get pregnant on Methotrexate you need to discuss this with your rheumatologist and make plans for a change in medication if pregnancy is desist
red. ...Read more

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Are there any risks to my new pregnancy/baby if I have fallen pregnant approx 3 weeks after a methotrexate shot for an ectopic pregnancy?

Are there any risks to my new pregnancy/baby if I have fallen pregnant approx 3 weeks after a methotrexate shot for an ectopic pregnancy?

Unlikely: The time it takes for 1/2 that medicine to leave your body is at the most 16 hours. Another half of the remainder in 16 and so on. By 3 weeks out there has been none in your system for some time. It can not effect the developing fetus if it is long gone. ...Read more

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Hello I had an ectopic pregnancy on october treated with methotrexate my af due tomorrow but I feel pain in my right side where the ectopic thank you?

Hello I had an ectopic pregnancy on october treated with methotrexate my af due tomorrow but I feel pain in my right side where the ectopic thank you?

Normal: It can be normal to feel a little pain, there could be some scar tissue there. I'm sorry you're going through this, but likely everything is okay. If you do become pregnant, make sure you see a doctor early in pregnancy to make sure the pregnancy is in the uterus. Best of luck. ...Read more

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Is it possible to have a healthy baby when I have taken methotrexate during the first four weeks of the pregnancy; & been off humira (adalimumab) during that month?

Is it possible to have a healthy baby when I have taken methotrexate during the first four weeks of the pregnancy; & been off humira (adalimumab) during that month?

Hi risk OB: High risk Obstetrician or Matetnal-Fetal Medicine specialist is whom you need to see asap, complex question to be answered on that limited platform ...Read more

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Is it safe to take methotrexate while pregnant or breastfeeding?

Is it safe to take methotrexate while pregnant or breastfeeding?

No: Methotrexate should never be used by pregnant or breastfeeding women. It blocks the actions of Folic Acid (a vitamin that all pregnant women should be taking). This medication can cause serious birth defects or fetal death if taken in pregnancy. It is excreted in breast milk and should not be taken while breastfeeding as it can interfere with a baby's metabolism. ...Read more

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Does methotrexate cause complications after molar pregnancy?

Does methotrexate cause complications after molar pregnancy?

Mmm? Let's C.: If you have had a molar pregnancy, the use of Methotrexate is for what condition. Obviously a molar pregnacy is virtually non-viable and occurs in 1/1000 pregnancies. If you are on methotrexate, you cannot get prenant, because mtx is an abortifacient. Mtx metabolites stay in your sytem for up to 2 & 1/2 months. It should not cause complications, if you are justified in taking it. Do nnot try! ...Read more

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Had my methotrexate injection 7 weeks ago for an ectopic pregnancy (about 3 weeks along). Still getting pos. Home pregnancy tests. What's going on?

Had my methotrexate injection 7 weeks ago for an ectopic pregnancy (about 3 weeks along). Still getting pos. Home pregnancy tests. What's going on?

Should be tracked: After Methotrexate it is important that your BHCG levels be tracked all the way down to zero. Usually this is done weekly. This is done to make sure that Methotrexate worked to treat the ectopic pregnancy. Also since it has been 7 weeks are you sure that this is not a new pregnancy? It is possible that you are pregnant again. See an Obgyn for a BHCG blood test. ...Read more

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Does methotrexate cause renal issues or other complications after a molar pregnancy?

Does methotrexate cause renal issues or other complications after a molar pregnancy?

Not commonly: This is a drug used to slow down cell division acting to control excessive immunity or malignancies.
The major toxicity is direceted at the liver, skin, GI tract and bone marrow cells.
Kidneys are usually spared. ...Read more

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How long does it take for methotrexate to clear out the body after use for ecotopic pregnancy? Will it cause infertility?

Unlikely: Low dose methotrexate as commonly used for problems like you have is cleared from the body in 48-72 hours. Infertility is a remote possibility as it can occur with any chemotherapy but Methotrexate is safer in this regard compared to alkylating agents. ...Read more

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I was diagnosed with an ovarian ectopic pregnancy. I was given methotrexate to help stop cell division. Will this affect future fertility?

I was diagnosed with an ovarian ectopic pregnancy. I was given methotrexate to help stop cell division. Will this affect future fertility?

No.: You are very fortunate it was caught early and could be treated without surgery. Your chances of pregnancy with two ovaries and fallopian tubes remaining will be normal.

http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/PMC3191676/ ...Read more

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Due to an ectopic pregnancy my wife had 2 methotrexate shots 2 months ago we are now 7 weeks my wife is weak and queezy is this from the shots?

Due to an ectopic pregnancy my wife had 2 methotrexate shots 2 months ago we are now 7 weeks my wife is weak and queezy is this from the shots?

See her doctor: While this may be unrelated, it still could be related to the injection or even an incompletely treated ectopic. She should follow up with the doctor who gave it her quickly. ...Read more

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I had a positive pregnancy test. Hcg was 330 48h after 454 and 48h after 660 I might have a methotrexate injection can I go to work the day after?

Methotrexate injecti: These injections are well tolerated, produce minimal if any side effects. So you should be able to go to work fine. ...Read more

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Does methotrexate cause fertility issues after molar pregnancy?

Does methotrexate cause fertility issues after molar pregnancy?

No: Methotrexate causes the abnormal molar pregnancy cells to stop growing. It will not affect fertility. It is important to avoid getting pregnant while taking the medication and for a few months after therapy is completed. Your doctor should give you details. ...Read more

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When is it safe to have sex when being treated with methotrexate for persistent pregnancy? Can it cause rupture?

When is it safe to have sex when being treated with methotrexate for persistent pregnancy? Can it cause rupture?

Listen to your Dr: I am presuming that you are taking methotrexate by a prescribing physician and that you have been given instructions to not have intercourse until your hormone levels have cleared your system. There are rare causes of persistently elevated pregnancy hormone and these need to be considered before determining that your treatment is complete. Please follow your doctors instructions and best of luck ...Read more

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Had ectopic pregnancy successfully treated with 1dose of methotrexate. How likely is Fallopian scarring after this?

Had ectopic pregnancy successfully treated with 1dose of methotrexate. How likely is Fallopian scarring after this?

It was already there: Most Fallopian tube (ectopic) pregnancies already had luminal (phenobarbital) adhesions or scarring that stopped the fertilized ovum from transporting itself down the tube to the uterus. Methotrexate was the least traumatic way to end the ectopic as opposed to surgery. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


Dr. Robert Lowe
341 Doctors shared insights

Rheumatrex (Definition)

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