Doctor insights on:
Can You Die From Thrombotic Thrombocytopenia Purpura
Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke. This is ...Read more
Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma. ...Read more
Range of symptoms: Ttp can involve many different organs. One can have renal dysfunction, fever, altered mental status, low platelet counts and hemolytic anemia. These signs can lead to symptoms of bleeding, bruising, petechiae, confusion, anemia, fatigue, and possible jaundice among other things. ...Read moreSee 1 more doctor answer
Rare disease: This is a rare but life-threatening disease; approx 2-3 cases per 100,000 population in the USA are seen. ...Read more
TTP is a serious: Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke. This is an absolute medical emergency. ...Read more
The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange. ...Read moreSee 1 more doctor answer
Autoimmune disease: Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few platelets in the blood. Check this site: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0001562/. ...Read moreSee 1 more doctor answer
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