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Doctor insights on: Can You Claritin And Benadryl Be Taken Together

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Can you Claritin and Benadryl (diphenhydramine) be taken together?

Can you Claritin and Benadryl (diphenhydramine) be taken together?

Yes: Most antihistamines are dosed at levels much below the toxic levels. Claritin was initially tested in drug studies at 4 times the current recommended dose. These same studies found that 10 mg yielded nearly equvalent effects as 40 mg. Since there is not a dramatic dose effect, increasing to higher levels rarely improves nasal symptoms. Benadryl (diphenhydramine) may have drying effects but sedation limits the dose. ...Read more

Dr. John Chiu
1,047 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Can Benadryl (diphenhydramine) and Claritin be taken together?

Can Benadryl (diphenhydramine) and Claritin be taken together?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. ...Read more

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Can you take Benadryl (diphenhydramine) and Claritin together?

Can you take Benadryl (diphenhydramine) and Claritin together?

Antihistamines: They are both antihistamines, so I wouldn't take them together. They both act similarly, so their effect would be too much together. Wait until one wears off before trying the other, about 24 hours or so. ...Read more

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Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Depends: They are both in the same family (antihistamines), but a few people have daytime symptoms so take non-sedating med (like loratadine) and its effect wears off before next day's dose, so take a sedating (/older) antihistamine (like benadryl) at bedtime for continued relief and to aid with sleep. If no heart / urinary / blood pressure issues and no other meds to conflict with, not likely a problem. ...Read more

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Claritin for children and Benadryl (diphenhydramine) together?

Not recommended: Both Claritin and Benadryl (diphenhydramine) are anti histamines. Claritin is long acting usually used once a day and Benadryl (diphenhydramine) is shorter acting. May be used 3-4 times a day. Since they both have action, recommended not to take it same time. ...Read more

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Can I take Claritin and Benadryl (diphenhydramine) together and drink it down with an alka-seltzer?

Can I take Claritin and Benadryl (diphenhydramine) together and drink it down with an alka-seltzer?

Maybe: Depending on what you are treating, I would space them out, take Claritin in the morning and Benadryl (diphenhydramine) at night. Benadryl (diphenhydramine) is sedating though, so be careful driving or operating machines. Not sure what you are treating though. I can see that with urticaria but for nasal allergies, I would use a nasal spray instead of a second antihistamine. Alka seltzer will only help pain because it has aspirin. ...Read more

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Can I take Zyrtec and Claritin together? Or can I take Zyrtec and Benadryl (diphenhydramine) to boost the Zyrtec? Will taking Mucinex DM along with Zyrtec help?

See your doctor: If your allergies are not controlled with one med alone, stepping up to a different med like flonase, nasonex, etc., will likely help you more than taking two antihistamines. Zyrtec and Claritin will not help much at all if you have a cold and not allergies, though Benadryl (diphenhydramine) can dry up secretions somewhat. You can add Mucinex if you also have a cough. Talk with your doctor about your symptoms. ...Read more

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Can I take diphenhydramine and loratadine together?

Can I take diphenhydramine and loratadine together?

Yes: Taking Loratadine in the morning and Diphenhydramine at night will help you avoid the drowsiness side effects of Diphenhydramine and help you if the Loratadine is not controlling your symptoms for the full 24 hours. ...Read more

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Can I take loratadine and diphenhydramine together?

Can I take loratadine and diphenhydramine together?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Can Benadryl (diphenhydramine) be taken with claritin?

Can Benadryl (diphenhydramine) be taken with claritin?

Zyrtec and Benadryl (diphenhydramine): Hello. These two antihistamines taken together will probably cause sedation. As physicians, we often times double up on antihistamines in challenging cases but I usually use non-sedating antihistamines when I do this. There are other medications that may work better than this combination. Check with your doctor for other options. ...Read more

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Can I take Benadryl (diphenhydramine) after taken a claritin?

Can I take Benadryl (diphenhydramine) after taken a claritin?

Not recommended: Claritin is a slow release, non-sedating antihistamine. Benadryl (diphenhydramine) is a faster onset sedating antihistamine. Taking both will have additive effects and possible adverse effects such as sedation. It is not recommended that you take both of these without the guidance of your doctor. If the Claritin is not adequate for your symptoms, there are many other medications that can be prescribed to help. ...Read more

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Can you take a generic Benadryl (diphenhydramine) when you have taken a luqi-gel claritin?

Yes you can: Yes you can occasionally take Benadryl (diphenhydramine) especially at night with Claritin if Claritin alone is not helping your symptoms but I will not recommend taking it for long periods and 3to 4 times a day of benadryl
most of the time try to take one or the other if it works for you or consult your doctor or an allergist. ...Read more

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Is loratadine like benadryl (diphenhydramine)?

Is loratadine like benadryl (diphenhydramine)?

Kinda mostly: Loratadine is a 'non-sedating antihistamine, ' and Diphenhydramine (/benadryl) is a sedating antihistamine (aka: older / h1 & h2 blocker), so yes, they are close cousins in intended effects--just differ in side effects. ...Read more

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Claritin versus Benadryl (diphenhydramine) for kids?

Work differently: Claritin in a non-drowsy antihistamine. It doesn't cause sleepiness, but you need to use it every day for it to work really well. It's lousy for severe allergic reactions because it takes days to be fully effective. Benadryl (diphenhydramine) causes drowsiness and only lasts for six hours, but is great for severe allergic reactions and works very quickly. If you're exposed and need help now, Benadryl (diphenhydramine) is better. ...Read more

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Can I take Claritin with benadryl (diphenhydramine)?

Can I take Claritin with benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Is Benadryl (diphenhydramine) and Claritin the same?

No and yes: They are both antihistamines but Benadryl (diphenhydramine) often causes drowsiness but is more effective in drying up the nose. It also has a shorter duration of action than claritin. ...Read more

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Is Claritin comparable to benadryl (diphenhydramine)?

Is Claritin comparable to benadryl (diphenhydramine)?

Both AH: Both act in similar fashion except that Benadryl (diphenhydramine) causes drowsiness and dry mouth in a much higher percentage of people and it works for just a few hours vs claritin's nearly 24 hours duration of action. ...Read more

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Can I take Benadryl (diphenhydramine) after claritin?

2 antihistamines: Even though both Benadryl (diphenhydramine) and Claritin are both antihistamines, there should not be significant interaction or side effects if taken at the usual doses. ...Read more

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Cani take Benadryl (diphenhydramine) with loratadine?

Probably yes.: Many people report their 'daily' non-sedating antihistamine in the am does not provide relief until next am. So, if no concerns for gu/heart/bp/med-conflict issues, then they often take a 'sedating' antihistamine at night for continued symptom relief and 'bonus' of sleep aid effect. ...Read more

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Can you take Benadryl (diphenhydramine) with claritin?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. However, if Claritin (loratadine) is not solving the problem, alternatives such as Allegra or zyrtec should be considered. ...Read more

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Does Claritin work better than benadryl (diphenhydramine)?

Not necessarily: Claritin is non-sedating at 10 mg and is a once daily medication. It has an onset of action approximately 30 minutes after taking. Benadryl (diphenhydramine) tends to work more quickly but lasts only 4-6 hours and can be sedating. ...Read more

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Take Claritin with benadryl, (diphenhydramine) is this okay?

Not really: These are both antihistamines. If both are needed then physician guidance should be sought. ...Read more

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Benadryl (diphenhydramine) vs. Claritin. Which one is better?

Benadryl (diphenhydramine) vs. Claritin. Which one is better?

Depends on reason: Both are antihistamines, both are effective for allergies. Benadryl (diphenhydramine) may be more potent and work better in some individuals, but causes much more sleepiness and the effects wear off more quickly than with claritin. ...Read more

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Can you take Benadryl (diphenhydramine) while taking claritin?

Yes: There is no interaction. Since Claritin does not cause drowsiness side effects should not be a problem. However, if Claritin is not solving the problem (hives or nasal allergies), alternatives such as Allegra or zyrtec should be considered. ...Read more

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Which goes to work faster? Claritin or Benadryl (diphenhydramine)

About the same speed: Unless Benadryl (diphenhydramine) is injected, either starts to work between 1-2 hrs. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Ashraf Abdel Azeem
537 Doctors shared insights

Claritin (Definition)

Claritin is a non-sedating antihistamine which is a kind of antihistamine type drug (common ...Read more