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Doctor insights on: Can You Chronic Myelogenous Leukemia Quickly

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What is chronic myelogenous leukemia?

What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

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Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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Dangers of chronic myelogenous leukemia?

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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How should I treat chronic myelogenous leukemia?

How should I treat chronic myelogenous leukemia?

By oncologist: This is a somewhat indolent form of leukemia which responds to treatment and can be carried for many years without major illenss. You could only have known about this if you had a bone marrow and blood test from your oncologist whose recommendations i would continue to follow. ...Read more

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What are the tests for chronic myelogenous leukemia?

What are the tests for chronic myelogenous leukemia?

Blood, bone marrow: Common tests include blood review, floww cytometry, and a bone marrowe and biopsy. ...Read more

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What are the symptoms of chronic myelogenous leukemia?

Fatigue: Fatigue is the most common symptom. Examination may show an enlarged spleen. The diagnosis is suspected by blood testing and confirmed by bone marrow biopsy. ...Read more

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What kind of disorder is chronic myelogenous leukemia?

Myeloproliferative: It is in a group of disorders referred to as myeloproliferative neoplasms. There are essentially four: chronic myelogenous leukemia, essential thrombocytosis, polycythemia rubra vera and myelofibrosis. Hope this helps. ...Read more

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What sort of disease is chronic myelogenous leukemia (c.M.L.)?

Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. ...Read more

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What are different ways to treat chronic myelogenous leukemia?

What are different ways to treat chronic myelogenous leukemia?

CML: CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case. ...Read more

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What's the type of inheritance of chronic myelogenous leukemia (cml)?

Not inherited: CML is associated with chromosome damage (the philadelphia chromosome). This is not inherited. The damage is to bone morrow stem cells and occurs long after birth. So the disease is not passed on to children. ...Read more

Dr. Liawaty Ho
60 doctors shared insights

Chronic Myelogenous Leukemia (Definition)

Chronic myelogenous leukemia (CML) is a cancer of the blood where there is an overproduction of white blood cells. Patients usually have no symptoms at diagnosis, and are found to have the disease after having ...Read more