Doctor insights on:
Can You Be A Carrier Of Cystic Fibrosis If You Have Two Healthy Parents
Yes: Cystic fibrosis (CF) is a genetic disease, but it requires two faulty genes to be expressed as a disease. A healthy person can carry one defective CF gene and not be affected by cf. If each member of a couple has a defective CF gene, they have a 25% chance of having a child who inherits both defective copies of the CF gene. Depending on the type of CF gene defect, that child could then develop cf. ...Read moreSee 1 more doctor answer
50%/time: Carrier parents pass either the normal or affected gene at equal(50%) frequency any time they conceive.In a million random parings, 25% would result in cf, 25% in non-carrier & 50% carriers. In practice, the parents could produce all cf, all carrier or all non- carrier kids. ...Read more
Do both parents have to be cystic fibrosis carriers in order for their child to be born with this disease?
Yes: Both parents have to be carriers and then their child has 25% chance of having the disease, 50% chance of being a carrier and 25% of not even being a carrier. The most common mutation causing cystic fibrosis is ?f508. But there are over 1500 mutations identified so far. ...Read moreSee 1 more doctor answer
What are the chances of passing on the Cystic Fibrosis gene if only one parent is a CARRIER? Other parent not a carrier.
50-50: One half of offspring will be carriers and one half will not be carriers. No offspring will be afflicted. Thanks for trusting HealthTap! ...Read more
Yes: It is a recessive trait, so both have to have the gene to pass it to a child. ...Read more
Poor growth/GI: In some children, 1st sign of CF is poor growth with child being small for age. This may be subtle enough that child continues to follow a growth curve on the growth chart, but in the lower percentiles until growth flattens out. Others have loose greasy stools as 1st sign. Frequent "bronchitis"/"sinus infections" that are thought to be just that until someone asks if that's just too many. ...Read more
Reinterpret question: If your question is can any parent have a child with cf, the answer is potentially yes. Both parents can have the mutation of cf, never know they carry it, & have a kid with the disorder.This is a common presentation. Adult males with CF have a 95% rate of sterility. CF females with good lung function can carry a pregnancy but the process may led to lung failure & death. ...Read moreSee 1 more doctor answer
Depends: This depends on the profile of the other parent. Their are dozens of mutations that can lead to CF, although most are the delta 509. Both parents must carry a CF related gene for an offspring to get it, and if so the risk is 25%. Carrier testing is available through specialty labs.If only one has trait ,zero. ...Read moreSee 2 more doctor answers
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