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Doctor insights on: Can White Males Have Sickle Cell Disease And If So Would Their Rbc Count Be Low

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Can white males have sickle cell disease? And if so would their RBC count be low?

Can white males have sickle cell disease? And if so would their RBC count be low?

Rarely, yes: Sickle cell disease is most common in blacks of sub-saharan west african ancestry. However, other ethnic groups can more rarely have the disease and they would much more likely have the "trait" rather than the "disease, " meaning they are only a carrier would have few, if any symptoms. Please see the answer by sg erman, md for statistics. ...Read more

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Dr. James Ball
354 doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more


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What diseases could cause RBC to start messing up inside of your body (besides sickle cell)?

What diseases could cause RBC to start messing up inside of your body (besides sickle cell)?

Variety: A variety of diseases can cause red cell issues--from size and number of red cells to breakdown of red cells because of a stress, as infection or immune related problems. The later may be associated with bilirubin (yellowness)--in eyes and skin. ...Read more

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I have sickle cell trait and have had low rbc for years despite taking iron supplements. Could these be related?

I have sickle cell trait and have had low rbc for years despite taking iron supplements.  Could these be related?

Unlikely: Sickle cell trait per se does not cause anemia. You need to see a hematologist for investigation of anemia, especially if your hemoglobin in less than 10 gm. ...Read more

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My father has a rare type of sickle cell that affects his WBC's instead of RBC's. Is there any information on this type of Sickle Cell Trait?

Get better info: Your dad may have a white cell disorder but it has nothing to do with sickle cell trait which is a specific red cell disorder. You need to consult with your day and find out the proper name for his disorder before we can comment. A doc may have compared it to sickle cell trait to try to explain it. ...Read more

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What are some of the more subtle symptoms of sickle cell anemia disease?

What are some of the more subtle symptoms of sickle cell anemia disease?

Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more

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How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read more

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Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Agree with Dr Diede: Sickle-cell trait & disease is an autosomal recessive inheritance from parents (genetics). Malaria is a parasitic infection. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life." ...Read more

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How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

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How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it takes 2 sickle genes to cause disease, one gene comes from each parent. Many parents carry this gene quietly, unknown to them because it doesn't make a single gene carrier sick. ...Read more

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My husband and I are both carriers of sickle cell anemia. What are our chances of our children exhibiting this disease?

25%: If both of you have sickle cell trait then each of you has one normal beta hemoglobin gene (a) and one with the sickle cell mutation (s). Your children will inherit one beta globin gene from each of you for a total of two. Therefore for each child that you have, there is a 25% chance of sickle cell disease (ss), a 50% chance sickle cell trait (as), and 25% chance of normal hemoglobin (aa). ...Read more

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Is it possible to be diagnosed with sickle cell anemia at 43? Even without ever experiencing any symptoms of the disease?

Is it possible to be diagnosed with sickle cell anemia at 43?  Even without ever experiencing any symptoms of the disease?

Possible, but...: Most people will have symptoms of enough severity to be diagnosed before adulthood. That being said, there is variation in the severity of sickle cell disease, most likely due to a number of other genes that modulate the symptoms. Thus, it probable is quite rare, but there could be that individual with a particular genetic makeup that has minimal disease that goes undiagnosed. ...Read more

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Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?

Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?

In theory 25%: Please remember these statistics apply to large population and therefore it is possible for a couple with sickle cell trait have children with and without sickle cell disease. ...Read more

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If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more

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Does sickle cell nemia has treatment? If so what are the medications? What are the foods that achild with sickle cell anemia eat? Is it tur that when some body reaches the age eighteen the disease disapears

Many questions: Sickle cell anemia is genetic and never disappears without bone marrow transplantation. Sickle cell anemia has medications that improve outcomes. Penicillin prophylaxis, empiric treatment of fever with antibiotics, and Prevnar (pneumococcal vaccine) / Pneumovax immunizations decrease risk of dying from infection. Hydroxyurea can decrease the frequency of painful crises and may minimize / delay sickle cell damage to body ...Read more

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My boyfriend & I have sickle cell anemia, our son will also inherit the disease. Should we wait until umbilical cord stops pulsating before clamping?

Doesn't matter: Sickle cell disease will affect his blood cells over time as they sickle with dehydration and illness, or as they live a shorter duration in the body. Generally there aren't any symptoms at birth, and nothing having to do with the cord will make a difference. In actuality, his fetal hemoglobin will be more protective from sickle cell, and treatments now focus on keeping fetal hemoglobin around. ...Read more

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What type of genetic disorder is sickle cell anemia or trait?

Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.). Normal HGB consists of paired protein chains (globin) and an iron containing part (heme). Patients with ssa inherit an abnormal beta-globin gene from each parent. Carriers have one normal beta-globin gene and one sickle beta globin gene. The carriers (trait) have no symptoms. ...Read more

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What kind of disorder is sickle cell anemia?

What kind of disorder is sickle cell anemia?

Genetic: With ss disease a genetic mutation changes the gene sequencing needed for normal hemoglobin production.The alteration changes the way the hemoglobin handles the oxygen molecule as it carries it in the blood.The blood cell then becomes distorted in the small capillaries and the spleen.The cell breaks down rapidly and or remains trapped.Anemia is a chronic problem. ...Read more

Male (Definition)

Male refers to the masculine gender, those people ...Read more