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Doctor insights on: Can White Males Have Sickle Cell Disease And If So Would Their Rbc Count Be Low

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Can white males have sickle cell disease? And if so would their RBC count be low?

Can white males have sickle cell disease? And if so would their RBC count be low?

Rarely, yes: Sickle cell disease is most common in blacks of sub-saharan west african ancestry. However, other ethnic groups can more rarely have the disease and they would much more likely have the "trait" rather than the "disease, " meaning they are only a carrier would have few, if any symptoms. Please see the answer by sg erman, md for statistics. ...Read more

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Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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What diseases could cause RBC to start messing up inside of your body (besides sickle cell)?

What diseases could cause RBC to start messing up inside of your body (besides sickle cell)?

Variety: A variety of diseases can cause red cell issues--from size and number of red cells to breakdown of red cells because of a stress, as infection or immune related problems. The later may be associated with bilirubin (yellowness)--in eyes and skin. ...Read more

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I have sickle cell trait and have had low rbc for years despite taking iron supplements. Could these be related?

I have sickle cell trait and have had low rbc for years despite taking iron supplements.  Could these be related?

Unlikely: Sickle cell trait per se does not cause anemia. You need to see a hematologist for investigation of anemia, especially if your hemoglobin in less than 10 gm. ...Read more

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My father has a rare type of sickle cell that affects his WBC's instead of RBC's. Is there any information on this type of Sickle Cell Trait?

Contradiction in: terms. WBCs do not have sickle cell disorder. Sickle cell disorder is due to a variant hemoglobin and only RBCs have hemoglobin in any quantity to undergo sickling. ...Read more

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What are some of the more subtle symptoms of sickle cell anemia disease?

What are some of the more subtle symptoms of sickle cell anemia disease?

Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more

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How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read more

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Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Agree with Dr Diede: Sickle-cell trait & disease is an autosomal recessive inheritance from parents (genetics). Malaria is a parasitic infection. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life." ...Read more

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How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

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Male (Definition)

Male refers to the masculine gender, those people ...Read more