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Doctor insights on: Can Wellbutrin Cause Fatigue

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Can lutera be the cause of severe fatigue/moodswings when combined with Effexor (venlafaxine) and wellbutrin?

Can lutera be the cause of severe fatigue/moodswings when combined with Effexor (venlafaxine) and wellbutrin?

Not likely: Birth control is not likely to cause that. Usually people are prescribed Effexor (venlafaxine) and wellbutrin for those exact symptoms. The underlying problem making you need those medications seems like a more likely cause.

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Dr. Alan Ali
784 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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My wife takes wellbutrin (bupropion) and Zoloft for depression. Will these meds cause tiredness and sleepiness? She is always tired.

My wife takes wellbutrin (bupropion) and Zoloft for depression. Will these meds cause tiredness and sleepiness? She is always tired.

Depression: These meds may cause the symptoms you mention. More importantly, is she seeing a Psychiatrist and Psychologist regarding her depression? They are a must! If she is seeing one or both of them she needs to report her symptoms.

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Became tired suddenly for months normal bloodwork-started Wellbutrin, (bupropion) helped some, been on it 2weeks, still tired but eased up some-will fatigue go away?

Became tired suddenly for months normal bloodwork-started Wellbutrin, (bupropion) helped some, been on it 2weeks, still tired but eased up some-will fatigue go away?

Great Question: Two weeks on an antidepressant and already starting to feel at the fatigue easing up. Usually takes 4-6 woks to get the full effect of east dose. So yes your fatigue should go away, but maybe not at this dose or medication by itself. I am so glad that you are seeing some results, now be patient, follow up as directed, keep taking your meds, therapy as needed. You are on recoveries road!

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Skin feels hot everywhere from my chest up. Headache, fatigue, but no other symptoms. Started wellbutrin (bupropion) XL 300mg a week ago but it's not side effect?

Skin feels hot everywhere from my chest up. Headache, fatigue, but no other symptoms. Started wellbutrin (bupropion) XL 300mg a week ago but it's not side effect?

Bothersome symptoms: Hi, I can see how he symptoms you describe would be extremely bothersome. It is a little difficult without more information to reach a conclusion about the source of these symptoms. However, some side affects can be serious, and I would encourage you to see the prescribing physician in order to have this condition further evaluated.

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Wellbutrin (bupropion) is for sure causing me bad GERD. BUT this medication works VERY WELL for my fatigue and depression, what can I do to prevent or stop GERD?

Wellbutrin (bupropion) is for sure causing me bad GERD. BUT this medication works VERY WELL for my fatigue and depression, what can I do to prevent or stop GERD?

Prevention methods: Includes avoiding certain foods/drinks, planning when you eat in relation to sleep/activity, and adjusting your sleep position. See comments section for a link to additional info. Over the counter meds may be useful, including omeprazole or Pepcid, (famotidine) but it is recommended this be coordinated with your provider as they are meant for short-term use and may be associated with side effects.

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Unable to take anti-dep due to extreme sleepiness or fatigue (zoloft, paxil, (paroxetine) wellbutrin, etc.). Is this a common occurence or am I an exception?

Unable to take anti-dep due to extreme sleepiness or fatigue (zoloft, paxil, (paroxetine) wellbutrin, etc.). Is this a common occurence or am I an exception?

Depression: Some people do not do well on anti-depressants. Consult with a clinical psychologist as you may do much better if your are in psychotherapy than simply taking meds. Also my workbook on depression is featured on the soundmindz. Org web site along with updated articles on depression treatment. Best wishes.

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Upbody muscl spas contious headac loss of conc fatigue all time I have been treated with ant dep for 3y with sight improv with wellbutr need any medic?

Anxiety ; Depression: Your symptoms may be part of depression, but also can happen with more anxiety features. I see in your additional information that you're taking Cymbalta (duloxetine) as well as wellbutrin? Cymbalta (duloxetine) may help more the with anxiety piece than the wellbutrin does. Overall it sounds like you've had a partial response to your medication (s) and need ongoing care -- including psychotherapy -- for recovery.

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Severe fatigue. Four years. Blood work fine, sleep study clear, on citalopram for dysthymia. And also welbutrin for fatigue. Still fatigued. Desperate?

Severe fatigue. Four years. Blood work fine, sleep study clear, on citalopram for dysthymia. And also welbutrin for fatigue. Still fatigued. Desperate?

Chronic Fatigue Synd: Other possibilities exist, including paradoxical reactions to your medications, issues with prior ebstein-barr infections, and even ms. Some agents have been shown to be helpful, including ritalin, (methylphenidate) provigil, nuvigil, etc. However, discuss with your physician if these are right for you.

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Is it safe to take wellbutrin (bupropion) with inositol? Will inositol cause wellbutrin (bupropion) to not work as well?

Is it safe to take wellbutrin (bupropion) with inositol? Will inositol cause wellbutrin (bupropion) to not work as well?

???: Why would you want to use inositol? Are you clear on dosage? Wellbutrin (bupropion) is used an antidepressant, but there are many better known medications to use than inositol. This is more complicated than it seems. Check with the physician who prescribed the wellbutrin (bupropion).

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Does wellbutrin (bupropion) affect your memory? If so, does it cause permanent damage? I have been on it ~2 years and find my memory/learning impaired.

Does wellbutrin (bupropion) affect your memory? If so, does it cause permanent damage? I have been on it ~2 years and find my memory/learning impaired.

NO!: Utrin is not a cause of progressive memory lossif anything it should improve memory by treating depression may be your depression is not fully treated see a specialist.

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Will wellbutrin (bupropion) sr cause more anxiety than xr?

Will wellbutrin (bupropion) sr cause more anxiety than xr?

Buproprion forms: Buproprion comes in different formulations: immediate release or regular, sr or slow release, and xl or extra long release. They are exactly similar in effect but not in delivery, what makes them to last longer in certain people. The most common side effect is insomnia (which depends on the formulation and time of dosing) and the gastrointestinal effects, which depends in taking it with meals.

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Can taking wellbutrin (bupropion) cause a loss of coordination?

Yes due to dizziness: Dizziness, however, is rare and for some people they would have a mild problem with incoordination due to having a racing heartbeat.

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Is Xanax (alprazolam) and or wellbutrin known to cause TIA episodes?

Is Xanax (alprazolam) and or wellbutrin known to cause TIA episodes?

TIA or seizure: Abrupt discontinuation of Xanax (alprazolam) while maintained on wellbutrin could precipitate a seizure. It is possible that with its wear-off throughout the day that it could cause seizure-like events as well. Abrupt discontinuation of alcohol is also discouraged while on wellbutrin.

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Does wellbutrin (bupropion) cause tingling all over body? Worse when I rub an area.

Possible s/e: Wellbutrin (bupropion) can cause tingling or paresthesias, but this is an uncommon side effect. If dose is lowered or stopped and tingling subsides, you know it was a side effect. Discuss with prescribing doctor who may want to adjust dose or try a different med. I hope this helps.

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Can just one tablet of wellbutrin (bupropion) XL 150mg cause an increase in anxiety and an out of it feeling for two or more days?

Can just one tablet of wellbutrin (bupropion) XL 150mg cause an increase in anxiety and an out of it feeling for two or more days?

Yes: The half-life of wellbutrin (bupropion) xl is about 24 hours, so it would still be in your system for 5 times that. Wellbutrin (bupropion) may exacerbate anxiety. Please contact your physician and let him/her know what you're experiencing.

Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more


Dr. Michael Rothman
1,268 Doctors shared insights

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