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Doctor insights on: Can We Use Deriva

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What is deriva used for?

What is deriva used for?

Deriva: Is the brand name for a medication which primarily contains Adapalene. (It is a retinoid like medication for treatment of acne). ...Read more

Deriva (Definition)

Adapalene is an acne agent which is a kind of skin-related medication. ...Read more


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What is the function of deriva aquaos gel?

What is the function of deriva aquaos gel?

Acne: Deriva Aqueous Gel is indicated for the topical treatment of acne vulgaris

Adapalene is a retinoid-like compound for the treatment of acne vulgaris. It is a naphthoic derivative with a methoxyphenyl adamantyl side chain. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris.



Adapalene binds to specific retinoic acid nuclear receptors but does not bind to the cytosolic receptor protein. It has been suggested that topical adapalene may normalize the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.


Analysis of cryosections, radioactive tracing and fluorescence studies in excised human skin have shown that adapalene gel penetrates into the epidermis and dermis (especially the pilosebaceous units). ...Read more

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Usage and results of adapalene gel microspheres 0.1 deriva MS?

Usage and results of adapalene gel microspheres 0.1 deriva MS?

Excellent RX: This is one of the formulations for adapalene and it is one of the better medications. I prefer the cream only because it dissolves in the skin better. The efficacy is really good for people suffering with acne. I hope it helps you as well. Put it on at bedtime to avoid any sun sensitivities in the daytime. ...Read more

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Is deriva a good medicine for acne. How long will it take to cure my acne?

Is deriva a good medicine for acne. How long will it take to cure my acne?

1. Yes. 2. A while: Deriva is adapalene, which is a retinoid and is good treatment for typical acne. It can be uses alone if a patient improves a lot with it. It can also be used with other gels or creams. As for how long... Improvement is in weeks to months, and cure is in months to years. ...Read more

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I have acne, I use deriva, this is my 5th week, bt I still get acne, what should I do. Why is that.

I have acne, I use deriva, this is my 5th week, bt I still get acne, what should I do. Why is that.

Doctor can recheck: After starting acne medication, one usually waits 1-2 months to see what the changes are. So, 5 weeks may not be long enough. However, the prescribing doctor can recheck at this time. He may decide to wait a few weeks longer, or may add another medication, because acne often needs a combination of medications for better benefits. ...Read more

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I hv acne, I used deriva for 3 weeks. I had to expose to sunlight for 5 days with out suns cream. Nw m black. Bt I didn't stop using the cream, ?

I hv acne, I used deriva for 3 weeks. I had to expose to sunlight for 5 days with out suns cream. Nw m black. Bt I didn't stop using the cream, ?

Side Effect of Med: Deriva will make your skin extra sensitive to the sun, this means that you should always use sunscreen and limit sun exposure. The first few weeks of use as your skin is adjusting to the treatment you will experience dryness, flaking, scaling, redness and irritation. You may have to use a prescription bleaching to lighten your skin. ...Read more

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I have normal acne...does smoking 10ciggs a day effect on my skin does it increase acne? Plz help me out....i m usin deriva bpo but its no effective

I have normal acne...does smoking 10ciggs a day effect on my skin does it increase acne? Plz help me out....i m usin deriva bpo but its no effective

Smoking does affect: acne, in part because it reduces blood flow to the skin (and everywhere else in the body). Nicotine is a vasoconstrictor, causing small arteries to clamp down. This raises blood pressure, increases risk of heart disease and other kinds of vascular problems, and also has effects on skin including increasing acne. There are many reasons to stop, perhaps your appearance can be one more. ...Read more

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My age is 35 years suddely from 1 year im getting pimples in bigger size im using deriva cms cream and kerancyl face fash but still im getting them?

My age is 35 years suddely from 1 year im getting pimples in bigger size im using deriva cms cream and kerancyl face fash but still im getting them?

SPIRONOLACTONE: Acne in adult women is related to hormones. Using birth control? Normal menstrual periods? Spironolactone, an anti androgen, is usually very effective. Usually 100mg a day. Usually clears acne in 3 months, then continue as maintenance. Not if pregnant or in kidney failure. Note that some birth control hormones make acne worse but some make it better. ...Read more

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I am 29 year old fat guy from sri lanka I met a dermatologist for a itchy behind neck wired thing he said it is keratosis and gave me deriva c gel?

I am 29 year old fat guy from sri lanka I met a dermatologist for a itchy behind neck wired thing he said it is keratosis and gave me deriva c gel?

Acanthosis?: A common condition in patients who are overweight is a acanthosis nigricans. This is a darkening and thickening of the skin, usually behind the neck and under the arms. Deriva c contains Adapalene which is a cousin of tretinoin, and may help thin the skin out and lighten the color a bit. Losing weight can be very helpful here, but if it persists, stronger creams exist that may help. ...Read more

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How to get rid of white head acne, I am using deriva bpo gel its not working?

How to get rid of white head acne, I am using deriva bpo gel its not working?

Scientific Rx: When benzoyl peroxide fails, as it often does, your physician may add topical Clindamycin and/or a topical retinoic acid derivative. The oral contraceptive pill, if it is right for you, may clear you. Your physician has other resources as well. Good luck. ...Read more

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Is it possible that adapalene + clindamycin phosphate gel deriva c be used only in mornings?

Is it possible that adapalene + clindamycin phosphate gel deriva c be used only in mornings?

Less effective: The produce when used at night has better absorption and less interaction with sunlight. ...Read more

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Hi. Am having dark red pimples on my cheeks and forehead big pimples.. I tried all. Now am using deriva cms. Is it good or tell me any other suggestion?

Hi. Am having dark red pimples on my cheeks and forehead big pimples.. I tried all. Now am using deriva cms. Is it good or tell me any other suggestion?

Acne: If you have used all the over the counter products including benzoyl peroxides it sounds like it is time to see a Dermatologist for further treatments. These may include oral and/ or topical antibiotics, retainoids, etc. ...Read more

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Age27, got pimples, dark spots. Applying deriva-cms cream. But not so much effective. What should I do for dark spots? Is suitable laser treatment?

Age27, got pimples, dark spots. Applying deriva-cms cream. But not so much effective. What should I do for dark spots? Is suitable laser treatment?

Yes there are lasers: You are using retinod cream and not getting good result from it. You should see a cosmetic dermatologist and there are lasers available to help with dark spots and it may help. You need to find a dermatologist who has lasers in their office. ...Read more

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I had a sudden outbreak of acne on my forehead as small pinpoints. I am using dermadew acne soap and deriva bpo gel since two months but no difference?

Sudden onset...: ...Of acne in an adult can sometimes be a sign of hormonal changes within the body. Medications can do it too. If benzoyl peroxide is not clearing it, you'd best see your dermatologist, who will prescribe something stronger and run some tests to rule out internal hormonal problems. ...Read more

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Can adapalene + clindamycin phosphate gel deriva c get rid of scars?

Can adapalene + clindamycin phosphate gel deriva c get rid of scars?

No: Clindamycin is an antibiotic no scar aide.Adapalene is a Retin-A derative that will control acne and help reduce fine wrinkles. The effects on scars will be minimal at best.
Scars require deep therapy such as fractionated co2 lasers, resurfacing lasers and deep chemical peels applied by properly trained physicians ...Read more

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Comedonal acne stage 3 using deriva cms gel from 1 month still breaking out leaving scars how long to continue please suggest facewash humid here?

Comedonal acne stage 3 using deriva cms gel from 1 month still breaking out leaving scars how long to continue please suggest facewash humid here?

Need prescription: If you are getting bad scars, this has to be more than comedonal acne (i don't understand the "comedonal acne stage 3"). This usually requires oral antibiotics, or if severe, isotretinoin. This can only be prescribed by a physician. Topical treatment will most likely not help. ...Read more

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Acne have reappeared, doc suggests to use deriva ms, saslic face wash, lactic acid capsules. After using this some have grown bigger and redness?

Acne have reappeared, doc suggests to use deriva ms, saslic face wash, lactic acid capsules. After using this some have grown bigger and redness?

Scientific stuff: Move on to something more effective. Different physicians are good at different things. Can you take the oral contraceptive pill? That might clear you. I'd consider switching you to benzoyl peroxide plus topical clindamycin, if this fails add a systemic antibiotic that's appropriate for you. ...Read more

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Adapalene gel microspheres what is it for?

Adapalene gel microspheres what is it for?

Acne: Most commonly for acne, its a good preparation of a newer form of retin-A and it aids in exfoliation. THe product is also used for fine lines, melasma, ...Read more

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Does adapalene gel and/or clindamyacin treat malasma?

Yes and no: The adapalene is a newer formulation of Retin-A and will promote exfoliation and possible help reduce the melasma
THe clindamycin however will have little if any effect ...Read more

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I use clindamyacin in the am adapalene at pm- but says to use clindamyacin twice a day. When should my second application be/can I use both together?

I use clindamyacin in the am adapalene at pm- but says to use clindamyacin twice a day. When should my second application be/can I use both together?

Adapalene is a: Once a day application. The new medicine epiduo contains adapalene and benzoyl peroxide (that is antibacterial like Clinda). Its all in one and once a day, if your insurance won't cover it, then I would do Clinda in am and you can put adapalene on at bedtime and cover with Clinda when dry. ...Read more

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Is adapalene gel used for jock itches?

Is adapalene gel used for jock itches?

No: It is the brand for an acne product called differin (adapalene). It would be very irritating in the groin region. ...Read more

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What are side effect of ap gel (adapalene gel)? . Thank you

What are side effect of ap gel (adapalene gel)? . Thank you

Skin irritation: Dryness, scaling, redness, stinging. All the side effects center around irritation of the skin. These side effects generally are worst at initiation of treatment and fade after a few weeks. ...Read more

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Hello. I'm currenty using Differin (adapalene) 0.1% and this id my third day. However im having terrible break outs since day 1. What do I do?

Hello. I'm currenty using Differin (adapalene) 0.1% and this id my third day. However im having terrible break outs since day 1. What do I do?

Relax: This is irritating when first used, so you may begin with twice a week and gradually increase. If acne seems worse at first this may actually be a clue that it is working. Keep with it. Expect to see desired result in 2 or 3 months. The generic, adapalene, is cheaper. Either way it comes as. 1% and. 3%. There are no other strengths. Consult a dermatologist for best result. ...Read more

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What are differin (adapalene) side effects?

What are differin (adapalene) side effects?

Very few: There are no reported systemic side effects but topical side effects include dry skin, scaling, redness, itching, burning, or sensitivity to light. ...Read more

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Does adapalene cream 0.1 help with wrinkles?

Does adapalene cream 0.1 help with wrinkles?

It is a retinoid: These creams have been shown to improve winkles but were primarily used for acne treatment. Many patients feel that their improvement faded after they stopped using the cream. The results do not compare with other forms of skin wrinkle improvement including laser treatments and even ipl in those patients with a lot of undesirable redness at the "crows feet" region. ...Read more

Dr. William Singer
138 Doctors shared insights

Adapalene (Definition)

Adapalene is an acne agent which is a ...Read more