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Doctor insights on: Can Uterine Fibroids Turn Into Cancer

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Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?

Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?

Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read more

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Dr. Barry Rosen
4,224 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How do I tell if I have uterine fibroids?

How do I tell if I have uterine fibroids?

Assess your symptoms: More common symptoms of uterine fibroids are: bleeding between periods; heavy menstrual bleeding (menorrhagia); menstrual periods that may last longer than normal; need to urinate more often; pelvic cramping or pain with periods; sensation of fullness or pressure in lower abdomen; pain during intercourse. Pelvic exam may be revealing. Pelvic imaging may be done. ...Read more

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Can uterine fibroids turn into cancer?

Can uterine fibroids turn into cancer?

No: The medical term for fibroids is leiomyomata. They are benign tumors that arise from smooth muscle cells; they do not become cancerous. The cancerous counterpart is called leiomyosarcoma. The problem is the inability to distinguish between the two without taking them out and looking at the cells under the microscope. Uterine tumors that enlarge quickly should be evaluated and possibly removed. ...Read more

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Can uterine fibroids lead to cancer?

Very rarely: Fibroids are benign tumors that only very rarely may become malignant. ...Read more

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Help please! could calcified uterine fibroids cause cancer?

Help please! could calcified uterine fibroids cause cancer?

Unlikely: But watch for increase in size in which case you need an experet gynecologist to advise you about required treatment. ...Read more

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L salpingo oophorectomy for simple cyst & pain. 5mos later, new onset R ovarian complex cyst w/ septation, uterine fibroid & 10mm L4 lesion. Cancer?

 L salpingo oophorectomy for simple cyst & pain. 5mos later, new onset R ovarian complex cyst w/ septation, uterine fibroid & 10mm L4 lesion. Cancer?

Not necessarily: While cancer is a possibility it is not the most likely diagnosis. More testing such as doppler flow studies on ultrasound can help with the diagnosis. It may well require surgery to know for sure. Good luck. ...Read more

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How much pain are uterine fibroids?

How much pain are uterine fibroids?

Varies greatly: Fibroids are benign (non cancerous) tumors of the uterus that are associated with painful, heavy periods. They can be treated with medications that are hormonal or non-hormonal, and they are also commonly treated surgically by removing the fibroid (s) or the entire uterus. ...Read more

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What are the tests for uterine fibroids?

What are the tests for uterine fibroids?

Tests: Initially your gynecologist may do an ultrasound. Also an MRI maybe done to better characterize your fibroids prior to treatment. ...Read more

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Fibroids (Definition)

Uterine fibroids are the most common pelvic tumor in women. 1 of every 3 women of child-bearing age have these tumors and up to 80% of african-american women have fibroids. They are often asymptomatic but they can also cause significant symptoms. It is the most common cause of heavy menstrual bleeding. Pelvic pain and increased urinary frequency ...Read more


Dr. John Lipman
631 doctors shared insights

Uterine Fibroids (Definition)

Uterine fibroids are the most common pelvic tumor in women. They occur in 1 of every 3 women regardless of race and up to 80 % of african-american women of child bearing age. They are often asymptomatic but they can cause significant symptoms (exe. Heavy menstrual bleeding, pelvic pain, increased urinary frequency). They ...Read more