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Doctor insights on: Can Statins Cause Elevated Creatinine Levels

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Can statin drugs increase creatinine level?

Can statin drugs increase creatinine level?

Yes: While very uncommon, all of the statin drugs have been known to cause muscle injury. The release from injured muscle of a substance called myoglobin can plug up the kidneys and cause the creatinine to rise. However, under those circumstances there is usually significant muscle pain or weakness and often the urine has a reddish appearance. Also a muscle enzyme (CPK) will be strikingly elevated. ...Read more

Statins (Definition)

Several drugs exist which lower cholesterol by inhibiting an enzyme in liver cells (hmg-coa reductase) that is involved in cholesterol synthesis. These all have generic names that end in -statin, e.g. Atorvastatin (lipitor) and Simvastatin (zocor). Since nearly all of the meds in this class have been shown to have similar cardiovascular benefits, we often discuss them ...Read more


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Do statins have any role in increasing serum creatinine? I well controlled DM type2 on oral antidiabetics and Hypertension controlled Ca channel block

Do statins have any role in increasing serum creatinine? I well controlled DM type2 on oral antidiabetics and Hypertension controlled Ca channel block

Maybe at high doses: LIMITED data has suggested that statins at higher doses, i.e. more than 40 mg simvastatin a day, might contribute to acute renal failure. This is counter intuitive because, in general, the effects of statins would be very favorable for those at risk for renal failure, such as yourself, with Type2 DM & hypertension. Most experts still recommend statins in this situation unless pt on dialysis. ...Read more

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I have moderately elevated cholesterol levels, and am prescribe statin drugs. Which control it nicely, but cause erectile dysfunction. Alternatives?

I have moderately elevated cholesterol levels, and am prescribe statin drugs. Which control it nicely, but cause erectile dysfunction. Alternatives?

Different dose or me: Compliance with medication is affected when problems arise, especially ed. Try switching to a different statin, lower the dose & combine with another cholesterol medication. Consider a stress test b/c ED and coronary artery blockage are connected. Decrease your animal fat including dairy and eat more plants. Add coq10 200mg to help with statin side effects and fish oil to help with triglyceride. ...Read more

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Does statins cause elevated creatine?

Does statins cause elevated creatine?

statins: Sometimes creatine phosphokinase levels are elevated in people taking statins. Some people having statin related muscle pains get relief from creatine supplements. What all this means is still under study. ...Read more

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Astt 88 ALT 188 non smoker occasional drinker 50 yo female on statins..Any other cause for the elevation? Never been elevated before

Astt 88 ALT 188 non smoker occasional drinker 50 yo female on statins..Any other cause for the elevation?  Never been elevated before

Combination: It may be a combination of factors. Discuss with your pcp. He may suggest some other tests, including an ultrasound of your liver. ...Read more

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What is the level of LDL where statins are needed?

What is the level of LDL where statins are needed?

LDL: This would depend on your past medical history,family history,and physical exam. If no history of diabetes,heart disease,stroke,hypertension it may not be indicate. If there is a positive finding then the LDL should be less than 80. Hope that is somewhat helpful. ...Read more

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Can statins or any diabetic medication cause pulptation?

Not generally.: Statins and antidiabetic meds are not generally associated with palpitations. Very high ( uncommon) or low blood sugars ( more common) could cause palpitations. ...Read more

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Could statin use effect memory and also cause word searching when speaking?

Could statin use effect  memory and also cause word searching  when speaking?

No: There is no credible evidence that statins cause memory loss. It is an "urban legend". The evidence supports statins are amazing drugs at lowering cholesterol and reducing heart attacks. ...Read more

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What are the best ways of reducing significantly high triglyceride levels  when statins are not helping?

What are the best ways of reducing significantly high triglyceride levels  when statins are not helping?

Lifestyle/meds: Weight loss through diet and exercise can have a very beneficial effect on triglycerides. If diabetic or hypothyroid, control over these helps. Omega3 fatty acids help but can raise LDL (fish oil 2 grams twice daily, 1/4 cup walnuts/day, use of olive oil for dietary oil such as on spinach salad). Fibrates (prescription) are very effective. ...Read more

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Can statins cause blindness?

Contraversial: “the news that a cholesterol-lowering drug could provide protection from the irreversible sight loss caused by glaucoma will be welcomed by those of us at risk of developing the condition in later life. However, further investigation is urgently needed before statins could be used in the future treatment of glaucoma.”. ...Read more

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Can taking a statin for elevated cholesterol, increase my fibro pain?

Can taking a statin for elevated cholesterol, increase my fibro pain?

Yes: As statin therapy can cause art heavies and myalgias so it can enhance your fibromyalgia symptoms. ...Read more

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Do statin drugs cause back pain?

Do statin drugs cause back pain?

Maybe: Statins are associated with myagias (muscle pain). Usually this is in the legs. Depending on the timing your pain may be associated with the statins. Talk to your doctor, see if there are med changes you could make. If there is no association, you would be fine on the statins. ...Read more

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Can statins cause back pain. Are some people unable to tolerate these drugs.?

Statin intolerance: Back pain is not the usual complaint but it's possible. Yes, some people are truly statin intolerant but many who think they are truly aren't . It's confusing so talk to your physician. ...Read more

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FM50, which LFT is required before starting statins for elevated lipid profile?

Liver functions.: Being the risk of adverse events can be elevated in people taking statins who have pre-existent liver dysfunction, screening for such with a liver function panel prior to starting a statin might be wise. ...Read more

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Why do statins have a larger effect on someone's cholesterol level than does diet?

Why do statins have a larger effect on someone's cholesterol level than does diet?

Basic biology: The vast majority of your cholesterol is made in your body, rather than coming in from what you eat. People like to criticize other people's food choices, but diet is only a tiny portion of vascular health. I'd rather see you exercising and eating what's comfortable and sensible for you, and adding a statin if you need it. ...Read more

Dr. Madhu Kandarpa
2,219 doctors shared insights

Creatinine (Definition)

Creatinine is a byproduct of creatine phosphate, which is present in muscles. Creatinine levels increase if the ...Read more