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Doctor insights on: Can Radiation Treatment Cause Avascular Necrosis

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? .

Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis?

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Perhaps: Certain chemo and radiation can cause avn. Certain cancers and disease can as well. It is best to discuss this with your oncologist or internist. ...Read more

Dr. Pietro Seni
215 doctors shared insights

Avascular Necrosis (Definition)

Also known as osteonecrosis, avascular necrosis is the death of bone from interruption of blood supply. This can result in tiny bone fractures and eventual destruction of the entire bone. It can be caused by trauma, blockage of circulation with lipids in the blood, certain diseases like sickle cell disease, Gaucher, and occasionally after exposure to corticosteroids. Sometimes, there ...Read more


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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? . .

Possible: Certain therapeutics, although not chemotherapy, that are commonly used in cancer patients can be associated with avascular necrosis (avn). Examples of these agents include: zometa, xgeva (denosumab) and avstin that can be associated with osteonecrosis of the jaw. Dexamethasone and radiation therapy can also cause avn. ...Read more

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Why does steroids cause avascular necrosis?

Why does steroids cause avascular necrosis?

We are not sure: We are not sure but there is a linkage seen whether it may be more related ti the underlying problem for which the steroids are given as treatment in the first place. ...Read more

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How does prednisone cause avascular necrosis?

How does prednisone cause avascular necrosis?

Still unknown: Even though there is this very well-established connection between chronic Prednisone use and avascular necrosis, how this occurs remains unclear. Numerous hypotheses abound. Some argue that increased lipids seen with steroids cause vessels to joints to clog, leading to oxygen starvation & bone death. A more popular view is that vessel (venous) walls undergo thickening, leading to poor blood flow. ...Read more

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Is there any reliable cure for avascular necrosis of the femoral head?

Is there any reliable cure for avascular necrosis of the femoral head?

Avascular necrosis: There is no medication to cure avascular necrosis, but the problem can be effectively treated with joint transplantation. It is important to avoid this surgery for as long as comfortably possible, because joint replacements have a limited lifespan and it is not fun to go through multiple procedures. ...Read more

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Is there a natural cure or any other alternative than prosthesis for avascular necrosis in hip. If no for how long would the prosthesis last. Im 30?

Is there a natural cure or any other alternative than prosthesis for avascular necrosis in hip. If no for how long would the prosthesis last. Im 30?

See details: There is no natural cure. In avn the blood supply to the head of the hip has been compromised to the extent that the bone has died and collapsed. If it reaches that stage replacing the femoral head is the only option. Early stage avn can be treated by non-weight bearing or core depression. The replacement should last 20+ years depending on your weight, activities, etc. ...Read more

Gamma Rays (Definition)

This is light of extremely short wavelengths typically produced either among the stars / in cosmic rays or by radioactive element decay. Gamma rays form the background of normal radiation in which we all live; it is substantially greater than the exposure we get from imaging scans or should get from ...Read more


Dr. Charles Glueck
455 doctors shared insights

Osteonecrosis (Definition)

Osteonecrosis is a condition in which part of a person's bone dies due to lack of blood flow to the area. The hip and shoulder are more likely to be affected, but osteonecrosis can also involve the knee, elbow, wrist, or ankle. Trauma to the bone can cause osteonecrosis, often there ...Read more