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Doctor insights on: Can Prozac Make You Tired

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Can Prozac (fluoxetine) make you tired?

Can Prozac (fluoxetine) make you tired?

Yes, but??!!: Is the tiredness primary to you seratonin problem or due to the treatment with prozac. You have to do the detective work and figure that out. Usually fluoxetine is activating and not sedating, but everyone is different. ...Read more

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Dr. Heidi Fowler
1,052 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Can Prozac (fluoxetine) make you feel tired and cold and give you anxiety and insomnia?

Can Prozac (fluoxetine) make you feel tired and cold and give you anxiety and insomnia?

Yes: Talk to your doctor about your symptoms. There are alternative treatments available for you. ...Read more

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Can upping a dose of prozac (fluoxetine) from 20mg to 40mg make you feel more tired than usual?

Can upping a dose of prozac (fluoxetine) from 20mg to 40mg make you feel more tired than usual?

Yes: This can be a side effect of fluoxetine. It may be easily managed by taking it at night; or, you may wish to consider changing to a different medicine. ...Read more

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Taking 20 mg of Prozac (fluoxetine) for 10 weeks in the morning makes me very tired can I take a couple of hours before bedtime?

Taking 20 mg of Prozac (fluoxetine) for 10 weeks in the morning makes me very tired can I take a couple of hours before bedtime?

Yes: If Prozac (fluoxetine) makes you drowsy but otherwise is helping, try taking a few hours before bedtime. Discuss with prescribing doctor who knows you best. Be sure to take same time every 24 hours. I hope this helps. Best wishes. ...Read more

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Took Prozac (fluoxetine) 10 mg for 2 weeks, was extremely tired and feeling cold, have not taken it for the past 5 days. How long until it is out of my system?

Two weeks to clear: It usually takes prozac (fluoxetine) two weeks to clear from the body. In your case, the prozac (fluoxetine) should be gone in about 9 more days. Hope this helps. Best wishes! ...Read more

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I've been on Prozac (fluoxetine) for years, 20 & now 40 mg. I've been off for about a month. I feel great, except for fatigue. Is the drug still active?

I've been on Prozac (fluoxetine) for years, 20 & now 40 mg. I've been off for about a month. I feel great, except for fatigue. Is the drug still active?

NO: That's GREAT...you are clear of the drug and probably do not need it for now! Make sure you report ANY change in your present Mood etc to your Doctor!

Good Luck
Hope this Helps!
Dr Z ...Read more

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Can 5 mg of Lexapro (escitalopram) be effective? 10 seems to strong came off 10 mg of Prozac 6 weeks ago for had by 10 mg of Lexapro (escitalopram) makes me tired and spacey.

Can 5 mg of Lexapro (escitalopram) be effective? 10 seems to strong came off 10 mg of Prozac 6 weeks ago for had by 10 mg of Lexapro (escitalopram) makes me tired and spacey.

Not really: 10mg is really a minimum dose to be effective, however if you are noticing a lot of side effects such as feeling tired or spacey, ask your doctor about a slower titration, and increase to 10mg only after 2 weeks or even a month on 5mg. And it really takes at least 20mg of Prozac (fluoxetine) to be effective, less than that and you just get side effects and no therapeutic benefit. ...Read more

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Day 2 on half a tablet lovan (prozac) I have been going to the toilet frequently! Feeling tired & nauseated. Also, worried about gaining weight : (thx?

Bowel and prozac (fluoxetine): Bowel symptoms are not uncommon and usually short-lived. Weight gain is uncommon, and when it happens, it tends to start about six months to a year after starting treatment. In my experience it seems to occur more often in women with severe stress during the period of weight gain, and it may be only coincidently appearing to be drug related. ...Read more

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What's the best medication for extreme snappiness, and extremely tired very irritable. I've tried Prozac, Wellbutrin etc.?

What's the best medication for extreme snappiness, and extremely tired very irritable. I've tried Prozac, Wellbutrin etc.?

Irritable: A medication is not the only way to fix this. Please think holistically. See doc to make sure you do not have medical issues such as thyroid or other hormone imbalances. How is your diet and exercise level? Are there decisions you need to make? Consider seeing a mental health pro for support and clarification. Peace and good health. ...Read more

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40 days on Prozac (fluoxetine) and I'm tired all day every day, will this pass? Its helping my anxiety and panic attacks immensely

40 days on Prozac (fluoxetine) and I'm tired all day every day, will this pass? Its helping my anxiety and panic attacks immensely

It may.: Be aware that anxiety/ panic can keep you in a heightened state of arousal. Removal of those symptoms may simply be revealing underlying exhaustion (or it could be a side effect). Take care. ...Read more

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I'm weening off 30mg of Prozac (fluoxetine) after being on it for a year, is it normal to have physical withdrawal symptoms, such as severe fatigue?

I'm weening off 30mg of Prozac (fluoxetine) after being on it for a year, is it normal to have physical withdrawal symptoms, such as severe fatigue?

Can happen: SSRI discontinuation syndrome symptoms may include: flu-like sx’s, insomnia, nightmares, vivid dreams, anxiety, tearfulness, depressed mood, confusion, irritability, restless legs, tremors, nausea, vomiting, cramps, loose stools, loss of appetite, dizziness, unsteady gait, flushing, sweating, headache, lethargy, imbalance, vertigo, ringing in ears, hypersensitivity to noise, sensation of ...Read more

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I am on Prozac (fluoxetine) 20 mg for anxiety disorder. Since a while I am feeling fatigue etc but mood ok. Does this mean my dose of Prozac (fluoxetine) needs adjustment?

Prozac (fluoxetine): I am happy your moods are better and probably the Prozac (fluoxetine) has helped you. The fatigue can be from multiple causes. I doubt the Prozac (fluoxetine) needs adjustment but it is true that raising the dose could help but only with your doctors agreement. ...Read more

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How does Prozac (fluoxetine) help with chronic fatigue syndrome?

How does Prozac (fluoxetine) help with chronic fatigue syndrome?

Prozac (fluoxetine): Mechanism still unknown. One theory is elevation of serotonin in brain which modulated energy level. ...Read more

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How much can Prozac (fluoxetine) help with chronic fatigue syndrome?

How much can Prozac (fluoxetine) help with chronic fatigue syndrome?

Sometimes none: Prozac (fluoxetine) has a variable benefit in cfs. In my experience, it can be tried but there are other meds which are generally more helpful. ...Read more

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Day 3 on lovan (prozac) half tablet. Tired all the time, no motivation. All I want to do is sleep. I know it's too early for affects, hopeless/drained?

Day 3 on lovan (prozac) half tablet. Tired all the time, no motivation. All I want to do is sleep. I know it's too early for affects, hopeless/drained?

Keep trying: As the medication activates in your system and reaches a therapeutic level, it is a good idea to be prepared. Take several minutes a day and walk, bend, stretch and get your body in motion. Get outside. Set an appointment to attend. Get used to an increase in structure. The medication will not do these things for you. It will only give you more resources to do what is necessary. ...Read more

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I take 20mg Prozac (fluoxetine) for anxiety. I am a college student so I am always tired during week days. Would drinking one iced latte or coffee a day affect me?

I take 20mg Prozac (fluoxetine) for anxiety. I am a college student so I am always tired during week days. Would drinking one iced latte or coffee a day affect me?

Probably not: College is definitely a rough time in everyone's life. One coffee per day should be fine. .. Just be cognizant of the timing and when you want to sleep. Hope that helps & best of luck! ...Read more

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Day 2 on Prozac (fluoxetine) feeling really depressed. Nausea, frequent use of toilet, lethargic, tired, no motivation, low, sad.

Day 2 on Prozac (fluoxetine) feeling really depressed. Nausea, frequent use of toilet, lethargic, tired, no motivation, low, sad.

Initial worsening: Its not uncommon to have some initial worsening beginning antidepressant and some GI side effects. This should improve after 2 weeks. If it doesn't contact your prescriber. Also tell them if you get suicidal. ...Read more

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My doctor prescribed me methylcobalamin injections after every 2 weeks to counter some fatigue or energy side effects of prozac (fluoxetine).Is this any help?

My doctor prescribed me methylcobalamin injections after every 2 weeks to counter some fatigue or energy side effects of prozac (fluoxetine).Is this any help?

Probably not: Methylcobalamin is a form of vitamin b12. It is useful for treating vitamin B12 deficiency, which can cause fatigue symptoms. However, there are many other causes of fatigue and low energy, including depression (is that why you're taking prozac (fluoxetine)?). Prozac (fluoxetine) itself may cause fatigue and low energy, although it usually doesn't. Methylcobalamin probably won't help that. ...Read more

Dr. Alan Ali
773 Doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more