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Doctor insights on: Can Polyarteritis Nodosa Lead To Vasculitic Neuropathy

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Dr. K. Olson Dr. Olson
3 doctors agreed:
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Can polyarteritis nodosa lead to vasculitic neuropathy?

Dr. K. Olson Dr. Olson
3 doctors agreed:
Can polyarteritis nodosa lead to vasculitic neuropathy?

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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Dr. Olav Jaren
1,351 doctors shared insights

Nerve Damage (Definition)

A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more


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Can celiac disease cause vasculitis?

Can celiac disease cause vasculitis?

Almost never: Vasculitis complicating celiac disease has been described but is extremely rare, and is not the most likely cause of any symptoms you might be experiencing. ...Read more

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Will neutropenia lead to raynauds disease?

Will neutropenia lead to raynauds disease?

Raynauds is an auto-: Immune disorder whose pathogenesis involves dysfunction within the adaptive compartment of the immune system. Neutrophils are a component of the innate immune system and is not related to raynaud's phenomenon. ...Read more

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Can masturbation lead to autoimmune diseases like lupus or multiple sclerosis?

Can masturbation lead to autoimmune diseases like lupus or multiple sclerosis?

NO relationship: This question has been asked and answered numerous times on this site. Masturbation does NOT cause disease or blindness! ...Read more

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Can rheumatoid arthritis cause raynaud's syndrome and can raynauds syndrome be fatal?

Can rheumatoid arthritis cause raynaud's syndrome and can raynauds syndrome be fatal?

Not directly: Raynauds can be present on occasion in patients with RA although I am sure you can say one causes the other. It is not fatal. ...Read more

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Can you explain the diagnosisof purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome?

Can you explain the diagnosisof  purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome?

No: This is a question that can be adequately answered only by complicated drawings, references to appropriate testing of several clotting factors, and analysis by a rheumatologist and a hematologist. In my patients such a discussion would take at least an hour. Hire a hematology consultant. ...Read more

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What leads to retinal vasculitis?

See details: Having a systemic vasculitis or connective tissue disorder that can have vasculitis as a component. ...Read more

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Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

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Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

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Can hashimoto's disease cause brain demyelinations ?

Can hashimoto's disease cause brain demyelinations ?

No: No, Hashimoto's does not cause brain demyelinations. Hashimoto's is an autoimmune thyroid dysfunction which will eventually cause hypothyroidism. During initial stage of Hashimoto's, thyroid function may remain normal or transiently elevated with self resolution. But in long term, most patient with Hashimoto's will develop hypothyroidism requiring thyroid hormone replacement ...Read more

Dr. Paul Grin Dr. Grin
2 doctors agreed:
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Can lupus cause tooth resorption? Can lupus cause Crohn's disease?

Dr. Paul Grin Dr. Grin
2 doctors agreed:
Can lupus cause tooth resorption? Can lupus cause Crohn's disease?

Definitely, no: The studies show that dentin is not recognized as a self structure by the immunologic system, being the component of the tooth makes it impossible. Hope it helps. ...Read more

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Can vascular conditions cause spleen damage?

Can vascular conditions cause spleen damage?

It depends: It depends what you mean by vascular conditions. Vascular conditions (aneurysms, dissections, strictures, etc) are very unlikely to cause spleen damage. On the other hand, certain blood diseases can clog the "filtering" capacity of the spleen and damage it. ...Read more

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Can scleroderma lead to pulmonary hypertension?

Can scleroderma lead to pulmonary hypertension?

Yes: If pulmonary hypertension occurs, it can severely affect quality of life and may cause premature death. Certain types of scleroderma such as limited cutaneous scleroderma are associated with pulmonary hypertension. Other types such as morphea are not. Screening is essential. ...Read more

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Can neuropathy go away?

Can neuropathy go away?

Depends: It depends on what the cause of neuropathy is. In majority of cases you can improve symptoms by treating the underlying cause and taking appropriate meds. ...Read more

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Dr. K. Olson Dr. Olson
3 doctors agreed:
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Can polyarteritis nodosa lead to vasculitic neuropathy?

Dr. K. Olson Dr. Olson
3 doctors agreed:

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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I want to know my options for treating polyarteritis nodosa?

I want to know my options for treating polyarteritis nodosa?

Limited: Despite many trials, corticosteroids are still the cornerstone of treatment. Cyclophosphamide may be added in more severe cases or in resistant cases of polyarteritis that are not hepatitis b related. Newer agents to treat this condition exist and treatment should only be attempted by a physician intimately familiar with the condition. ...Read more

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What is the definition or description of: Polyarteritis nodosa?

What is the definition or description of: Polyarteritis nodosa?

Polyarteritis nodosa: Polyarteritis nodosa (panarteritis nodosa, periarteritis nodosa or Kussmaul disease) is a disease which causes swelling and inflammation to arteries. ...Read more

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Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more

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Is polyarteritis nodosa always an autoimmune disease?

Is polyarteritis nodosa always an autoimmune disease?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It is immune mediated and exact cause is not known. ...Read more

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What are the tests for polyarteritis nodosa?

What are the tests for polyarteritis nodosa?

Polyarteritis nodosa: Diagnosis made by clinical suspicion based on patient symptoms and findings .Lab findings may include elevated wbc, ESR , CRP and in some patients positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied. ...Read more

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What are the symptoms of polyarteritis nodosa?

What are the symptoms of polyarteritis nodosa?

Ployarteritis nodosa: Symptoms depends on organ or system affected. Symptoms are fatigue , fever, muscle , joint pains, unexplained weight loss, anorexia . Based on organ involved kidney failure, hypertension due to kidney involvement, stroke , seizures due to brain involvement, abdominal pain due to bowel perforation , chest pain , heart attack due to heart involvement wrist drop, foot drop due nerve involvement. ...Read more

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What is inflammatory polyarteritis nodosa? How is it treated?

Inflammation - vesse: It is inflammation of blood vessels, Depending on which blood vessel are involved is where the symptoms and signs are. as the muscle is inflammed, the vessel narrows interferring with the blood flow. This is how polyarteritis causes its problems. The physician will evaluate the patient, get labs and perform imaging to help evaluate for therapy. ...Read more

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What new research is there regarding vasculitis and polyarteritis nodosa?

What new research is there regarding vasculitis and polyarteritis nodosa?

Treatment.: Polaryarteritis & temporal arteritis, are found to be quite treatable without high dose Prednisone and all it's side effects. The new drugs are tnf-a inhibitors and new research shows quick remission in most cases. ...Read more

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I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

Polyarteritis nodosa: Diagnosis made by symptoms and findings which may include elevated wbc, ESR , CRP and in some positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied . At times biopsy is targeted for affected tissues. ...Read more

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What causes polyarteritis nodosa?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It can affect infants. Dilated arteries and strictures resemble rosary beads. ...Read more

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If my younger sister has polyarteritis nodosa, what is likelihood that her older brother myself, will have it too, i have no symptoms at the moment?

If my younger sister has polyarteritis nodosa, what is likelihood that her older brother myself, will have it too, i have no symptoms at the moment?

Unlikely: This is a very rare disease to have. It most commonly is associated with untreated hepatitis B virus. It can also be idiopathic, meaning, no associated cause is found. With autoimmune diseases in general, there is some inherited component typically, but it does not mean that exact disease will be inherited by another family member or that a family will even develop an autoimmune disease. ...Read more

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63 yr old male. Just diagnosed with diabetic peripheral neuropathy. Can this lead to circulation problems. A1c is 7. Blood sugar levels are in range.

63 yr old male. Just diagnosed with diabetic peripheral neuropathy.  Can this lead to circulation problems. A1c is 7. Blood sugar levels are in range.

Can lead to PROBLEMS: I am unclear on what you mean with the term "circulation problems." are you referring to blockage of the cirulation by blood clots, atherosclerosis? Diabetes is often said to be a "small vessel type of disease process." meaning that infarcts and strokes occur in limited parts of the brain or heart. Truth though is diabetes affects large vessel as well...Meaning that clots can form and travel. ...Read more

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Does a cure exist for polyarteritis?

Does a cure exist  for polyarteritis?

No: Polyarteritis nodosa is a type of vasculitis (blood vessel inflammation) that is often fatal if untreated. Fortunately, medicines exist that can control the symptoms and the disease can go into remission. However, that is not a cure. ...Read more

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Can neuropathy go away?

Depends: It depends on what the cause of neuropathy is. In majority of cases you can improve symptoms by treating the underlying cause and taking appropriate meds. ...Read more

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Dr. Bennett Machanic
1,473 doctors shared insights

Neuropathy (Definition)

A condition in which a person experiences weakness, numbness, and pain from nerve damage, usually in ...Read more


Dr. Lynne Weixel
842 doctors shared insights

Nerve Pain (Definition)

Neuralgia is a sharp, shocking pain that follows the path of a nerve and is due to irritation or ...Read more