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Doctor insights on: Can Pituitary Cancer And High Prolactin Levels Cause Breast Cancer

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Dr. Barry Rosen
1,337 doctors shared insights

Breast Cancer (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


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Do high prolactin levels lead to breast cancer?

Do high prolactin levels lead to breast cancer?

Unclear: There are reports that women with higher prolactin levels were associated with an increased risk of breast cancer. However the cause and effect is not completely understood. Among postmenopausal women, prolactin levels were higher among hormone users and lower among obese women. Meaning higher prolactin levels might be associated with already known risk factors for developing breast cancer. ...Read more

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Do high estrogen levels cause breast cancer in men?

Do high estrogen levels cause breast cancer in men?

IT'S A RISK FACTOR: Prolonged exposure to estrogen is a risk factor for breast cancer in men. Obesity, liver cirrhosis and high alcohol intake can lead to a high estrogen state. ...Read more

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Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

PCOS: PCOS can increase androgens in patients regardless of their weight. The effects on Estrogen are less clear as these levels fluctuate and typically would not be tested in PCOS. The LH and FSH levels are checked but not Estrogen. The effects of Phytoestrogens such as soy on the risk of breast cancer are debatable. There is not specific recommendation for PCOS patients to avoid them ...Read more

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Can breast cancer cause high fai and low shbg?

Can breast cancer cause high fai and low shbg?

Guessing : "free androgen index" and "sex-hormone binding globulin"? That is news to me. There's a few old correlations with obesity but nothing i could find more recently. I'd reiterate my colleague's request to keep the abbreviations / acronyms to a minimum -- there's way too both in real life and in medicine. I'm wondering why you ask, but i hope this was helpful. ...Read more

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Is high blood Calcium caused by Metestatic Breast Cancer Reversable?

Is high blood Calcium caused by Metestatic Breast Cancer Reversable?

Yes: Osteolysis and hypercalcemia not uncommon in metastatic breast Ca to bone. It is primarily mediated by osteoclast not a direct effect of tumor cells but by factors that stimulate osteoclast production and action. Breast Ca cells in bone also express parathyroid-related protein (PTHrP). Locally produced PTHrP causes osteolysis that can be ameliorated by administration of anti-PTH mAbs and chemo ...Read more

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Could pregnancy trigger breast cancer?I am high risk, and am screened yearly.But could a pregnant cause a genetic bc to grow when otherwise it wouldn't?

Could pregnancy trigger breast cancer?I am high risk, and am screened yearly.But could a pregnant cause a genetic bc to grow when otherwise it wouldn't?

Yes and No: Women who are at increased risk for breast cancer can end up getting a breast cancer in pregnancy due to the growth hormones in pregnancy. I don't think pregnancy could 'start' a bc, but can accellerate.Be sure to survey your breasts with self exams and ask dr. To perform exam at beginning of pregnancy as well. Any lump or mass report immediately. This goes for pregnancy as well as postpartum. ...Read more

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No family history of breast cancer. 44 years old. Mammo shows small cluster of microcalcification in mlo view only of upper right breast. I do consume very high levels of caffeine. Do not smoke. Healthy diet and exercise. First abnormal Mammo. I do ha

No family history of breast cancer.  44 years old. Mammo shows small cluster of microcalcification in mlo view only of upper right breast. I do consume very high levels of caffeine.  Do not smoke. Healthy diet and exercise.  First abnormal Mammo.  I do ha

This is a common: finding Mammograms pick up both in malignant and Non malignant Breast conditions. POINT IS IT ABSOLUTELY NEEDS FOLLOW UP by a Breast Specialist! The Provider who ordered the study should be your first contact! Hope this helps! Dr Z ...Read more

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Dr. Barry Rosen
4,224 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Samuel Freedman
731 doctors shared insights

Prolactin (Definition)

The pituitary gland makes many hormones. After delivery of a baby, the pituitary gland pours out prolactin which causes the breasts to produce milk. It may be abnormally produced and cause enlarged ...Read more