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Doctor insights on: Can Neulasta Be Taken With Weekly Taxol Chemo Treatments

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Neulasta (pegfilgrastim) with weekly taxol, is this okay?

Neulasta (pegfilgrastim) with weekly taxol, is this okay?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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Dr. Devon Webster
971 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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Is neulasta (pegfilgrastim) needed with weekly taxol?

Is neulasta (pegfilgrastim) needed with weekly taxol?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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Tx is bi-weekly with fu5 + avastin (bevacizumab). Cea is reliable, tested at start of tx. Cea drops significantly with neulasta/neopogen tx following chemo. Why?

Tx is bi-weekly with fu5 + avastin (bevacizumab). Cea is reliable, tested at start of tx.  Cea drops significantly with neulasta/neopogen tx following chemo.  Why?

Unclear question: Cea dropping is due to chemotherapy. It is a good sign, indicates chemo is working. Neupogen/neulasta are given to increase white cell counts. These are probably unnecessary if you are only taking f-5-fu based chemo. ...Read more

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After taxol (paclitaxel) reaction for 3b squamous nsclc, husband is on weekly treatment, 2 wks abraxane, then 1 w/ abraxane/carboplatin. Is it normal & effective?

After taxol (paclitaxel) reaction for 3b squamous nsclc, husband is on weekly treatment, 2 wks abraxane, then 1 w/ abraxane/carboplatin.  Is it normal & effective?

Yes its a good alter: If your husband has allergy to Taxol, (paclitaxel) then using Abraxane as an alternative is a good decision. This treatment works well in about half (50%) of the patients, not in the others. You will know within 6 to 8 weeks of chemotherapy treatments. ...Read more

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What is the role of Taxol (paclitaxel) in chemotherapy?

What is the role of Taxol (paclitaxel) in chemotherapy?

Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more

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Can you tell me about breastcancer, chemotherapy and experiences with Taxol (paclitaxel) ?

Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more

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I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?

I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?

Lips and skin: Pharmacists are, in my opinion, the best folks to help you select the best 'over the counter" creams for your lips and something else for your skin.
If you decide to go that route please let me know how things are going. ...Read more

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Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not(speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more

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I'm 8 days out from round 1 of chemo, had a neulasta (pegfilgrastim) shot day 2, took Claritin 2 days pre- through 3 days post- chemo, but now have severe bone pain?

I'm 8 days out from round 1 of chemo, had a neulasta (pegfilgrastim) shot day 2, took Claritin 2 days pre- through 3 days post- chemo, but now have severe bone pain?

Neulasta (pegfilgrastim): You don't mention what chemotherapy you are receiving, or why you are receiving it, however, Neulasta (pegfilgrastim) commonly causes bone pain for several days after it is injected. Talk to your oncologist or the nursing staff about this. ...Read more

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Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?

Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?

Hand swelling and pain: This is most likely side effect of Taxol (paclitaxel). Some side effects of taxol (paclitaxel) are neuropathy which is damaging of the nerve fibers joint pains and sometimes swelling of extremities. Most of this side effects get better after stopping the treatment but the neuropathy sometimes persists and requires lifelong medications. Follow up with your oncologist and discuss this problem. ...Read more

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I have stage 4 tnbc before i was to start AC chemo my platelets were too low 85. Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?

I have stage 4 tnbc  before i was to start AC chemo my platelets were too low 85.  Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?

Further eval: If platelets were low before starting, il'd worry that you have spread to the bone marrow. In that case, you would get treatment anyway, no matter what the counts, in hopes of clearing the marrow. If your liver enzymes are high, there may be liver metastases.
I don't know your'e whole story, but i would strongly consider treating with something like Carboplatin and abraxane. Also check her2 again. ...Read more

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AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more

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Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Ask your Oncologist: This is a question patients often ask their oncologists when he/she recommends chemotherapy.. So you should ask and see the answer you get. Then we can also verify it for you, if needed. ...Read more

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Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read more

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My mom is undergoing chemotherapy-taxol-is urine incontinence a side effect?

No!: It is not due to Taxol (paclitaxel). Get her doctor to check her for the cause...it could be infection in the bladder. ...Read more

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Finished taking Taxol (paclitaxel) chemotherapy, hands and fingers swollen. What can I do for swelling to go away?

Finished taking Taxol (paclitaxel) chemotherapy, hands and fingers swollen. What can I do for swelling to go away?

It will go away: All the changes in your skin and hair will go away in a short time after your last dose of Taxol (paclitaxel). Most patients are fully recovered in 3 to 6 months. So do not worry about the swelling...there is no treatment for it but your body are repair and normalize it slowly but surely. ...Read more

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Currently taking Taxol (paclitaxel) chemotherapy, have a cold. Hurts to swallow, chest hurts when I cough. Is there anything I can do?

Currently taking Taxol (paclitaxel) chemotherapy, have a cold. Hurts to swallow, chest hurts when I cough. Is there anything I can do?

Take pain meds: You should report this problem to your oncologist and ask for medication for what appears to be virus/Flu type of sore throat. If your blood counts are not low, you could also use tylenol (acetaminophen) for pain control but make sure that you do not have fever. With low counts or Fever, tylenol (acetaminophen) is not safe unless your doctor is monitoring your condition. ...Read more