Top
30
Doctor insights on: Can Neulasta Be Taken With Weekly Taxol Chemo Treatments

Share
1

1
Neulasta (pegfilgrastim) with weekly taxol, is this okay?

Neulasta (pegfilgrastim) with weekly taxol, is this okay?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

Dr. Devon Webster
972 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


2

2
Is neulasta (pegfilgrastim) needed with weekly taxol?

Is neulasta (pegfilgrastim) needed with weekly taxol?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

4

4
Tx is bi-weekly with fu5 + avastin (bevacizumab). Cea is reliable, tested at start of tx. Cea drops significantly with neulasta/neopogen tx following chemo. Why?

Tx is bi-weekly with fu5 + avastin (bevacizumab). Cea is reliable, tested at start of tx.  Cea drops significantly with neulasta/neopogen tx following chemo.  Why?

Unclear question: Cea dropping is due to chemotherapy. It is a good sign, indicates chemo is working. Neupogen/neulasta are given to increase white cell counts. These are probably unnecessary if you are only taking f-5-fu based chemo. ...Read more

5

5
After taxol (paclitaxel) reaction for 3b squamous nsclc, husband is on weekly treatment, 2 wks abraxane, then 1 w/ abraxane/carboplatin. Is it normal & effective?

After taxol (paclitaxel) reaction for 3b squamous nsclc, husband is on weekly treatment, 2 wks abraxane, then 1 w/ abraxane/carboplatin.  Is it normal & effective?

Yes its a good alter: If your husband has allergy to Taxol, (paclitaxel) then using Abraxane as an alternative is a good decision. This treatment works well in about half (50%) of the patients, not in the others. You will know within 6 to 8 weeks of chemotherapy treatments. ...Read more

6

6
What is the role of Taxol (paclitaxel) in chemotherapy?

What is the role of Taxol (paclitaxel) in chemotherapy?

Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more

7

7
Can you tell me about breastcancer, chemotherapy and experiences with Taxol (paclitaxel) ?

Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more

8

8
I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?

I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?

Lips and skin: Pharmacists are, in my opinion, the best folks to help you select the best 'over the counter" creams for your lips and something else for your skin.
If you decide to go that route please let me know how things are going. ...Read more

9

9
Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not(speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more

10

10
I'm 8 days out from round 1 of chemo, had a neulasta (pegfilgrastim) shot day 2, took Claritin 2 days pre- through 3 days post- chemo, but now have severe bone pain?

I'm 8 days out from round 1 of chemo, had a neulasta (pegfilgrastim) shot day 2, took Claritin 2 days pre- through 3 days post- chemo, but now have severe bone pain?

Neulasta (pegfilgrastim): You don't mention what chemotherapy you are receiving, or why you are receiving it, however, Neulasta (pegfilgrastim) commonly causes bone pain for several days after it is injected. Talk to your oncologist or the nursing staff about this. ...Read more

11

11
Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?

Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?

Hand swelling and pain: This is most likely side effect of Taxol (paclitaxel). Some side effects of taxol (paclitaxel) are neuropathy which is damaging of the nerve fibers joint pains and sometimes swelling of extremities. Most of this side effects get better after stopping the treatment but the neuropathy sometimes persists and requires lifelong medications. Follow up with your oncologist and discuss this problem. ...Read more

12

12
I have stage 4 tnbc before i was to start AC chemo my platelets were too low 85. Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?

I have stage 4 tnbc  before i was to start AC chemo my platelets were too low 85.  Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?

Further eval: If platelets were low before starting, il'd worry that you have spread to the bone marrow. In that case, you would get treatment anyway, no matter what the counts, in hopes of clearing the marrow. If your liver enzymes are high, there may be liver metastases.
I don't know your'e whole story, but i would strongly consider treating with something like Carboplatin and abraxane. Also check her2 again. ...Read more

13

13
AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more

14

14
Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Ask your Oncologist: This is a question patients often ask their oncologists when he/she recommends chemotherapy.. So you should ask and see the answer you get. Then we can also verify it for you, if needed. ...Read more

15

15
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read more

17

17
My mom is undergoing chemotherapy-taxol-is urine incontinence a side effect?

No!: It is not due to Taxol (paclitaxel). Get her doctor to check her for the cause...it could be infection in the bladder. ...Read more

18

18
Finished taking Taxol (paclitaxel) chemotherapy, hands and fingers swollen. What can I do for swelling to go away?

Finished taking Taxol (paclitaxel) chemotherapy, hands and fingers swollen. What can I do for swelling to go away?

It will go away: All the changes in your skin and hair will go away in a short time after your last dose of Taxol (paclitaxel). Most patients are fully recovered in 3 to 6 months. So do not worry about the swelling...there is no treatment for it but your body are repair and normalize it slowly but surely. ...Read more

19

19
Currently taking Taxol (paclitaxel) chemotherapy, have a cold. Hurts to swallow, chest hurts when I cough. Is there anything I can do?

Currently taking Taxol (paclitaxel) chemotherapy, have a cold. Hurts to swallow, chest hurts when I cough. Is there anything I can do?

Take pain meds: You should report this problem to your oncologist and ask for medication for what appears to be virus/Flu type of sore throat. If your blood counts are not low, you could also use tylenol (acetaminophen) for pain control but make sure that you do not have fever. With low counts or Fever, tylenol (acetaminophen) is not safe unless your doctor is monitoring your condition. ...Read more

20

20
My mom is undergoing chemotherapy-currently taxol- for breast cancer-is neuropathy that comes and goes a normal side effect?

My mom is undergoing chemotherapy-currently taxol- for breast cancer-is neuropathy that comes and goes a normal side effect?

Yes: It is one of the side effect , speak to the oncologist , it is good drug to stop the cancer cell growth. Good Luck ...Read more

21

21
I have triple negative stage 3 breast cancer. Ac followed by t. Neulasta (pegfilgrastim) for ac....Is it routine to continue neulasta (pegfilgrastim) for t treatments?

Neulasta (pegfilgrastim): For ac regimen dose dense (every 2 weeks, we recommend neulasta). After that i usually give Taxol (also called paclitaxel) weekly x 12 weeks and Neulasta (pegfilgrastim) is not used for weekly regimen. Some oncologists prefer Taxol every 3 weeks x 4 doses (big dose taxol), than it can be used. Weekly regimen have robust data and is well tolerated and we can avoid side effects of Neulasta (pegfilgrastim) (which can be rough). ...Read more

22

22
Husband is being put on carboplatin/arbraxane for 3b squamous nsclc, after taxol (paclitaxel) reaction. Concurrent radation therapy. Is this an effective plan?

Yes it is!: This is the current recommended chemotherapy(along with concurrent radiotherapy) treatment plan. Hopefully it should work well. But it will take 6-8 weeks to see the full benefit. ...Read more

23

23
What are some good treatments for nsvn other than chemo?

What are some good treatments for nsvn other than chemo?

Immunosuppressants: Non systemic vasculitic neuropathy is treated with immunosuppressants including steroids, Cyclophosphamide (a type of chemo), mycophenolate and azathioprine. Ask your doctor about options. There are several choices of oral drugs and you may need to try several to find the one that works best for you. ...Read more

24

24
Is chemo really an effective cancer treatment?

Is chemo really an effective cancer treatment?

It depends: Chemotherapy is very effective for treatment of some cancers. It can be curative in some cases and prolong life in others. However, chemotherapy, due to its nature, is toxic, and any treatment with chemotherapy should involve a discussion of risks and benefits (and possible outcomes) before starting. ...Read more

25

25
What is a treatment for cancer other than chemo?

What is a treatment for cancer other than chemo?

3 modalities: There are 3 modalities to treat cancer- surgery ( if localized and if possible to be done) . A radiation therapy and chemotherapy. Treatment of cancer can use only one modality or could require combination of 2 or all of the above- depending on the type of cancer, the stage, the goal of therapy and overall condition of the patient. ...Read more

26

26
Any suggestions to counter fatique from chemo treatments?

Yes: I know it sounds stupid- get more rest. Studies suggest fatigue is also improved by regular mild exercise- walking, getting outside, doing active things you like and resting when tired. Daytime naps of 30 min or less are often helpful. (longer ones do not work as well) if you are severely anemic, in my experience, sometimes transfusions help depending upon the degree of anemia. ...Read more

27

27
Could there be a difference between radiation treatment and chemo?

Could there be a difference between radiation treatment and chemo?

Yes: Radiation therapy is the focused use of high energy x-rays that only work where we aim them at and have the ability to destroy tumor cells. Treatment is like getting an x-ray. Chemotherapy is medical therapy that is taken either by mouth or through an IV and goes throughout your whole body's bloodstream and affects all organs. It tracks down microscopic cancer cells in blood to kill them. ...Read more

28

28
Can you tell me about the most common treatment for cancer along with chemo?

Can you tell me about the most common treatment for cancer along with chemo?

Depends on...: ...The type of cancer but in a nutshell, there is surgery, radiation therapy in one of its many forms, endocrine (hormone) therapy, immunotherapy (using the body's immune system to fight the cancer), and targeted therapies which work on the molecular mechanisms that make cancer cells go. Some treatments overlap more than one category. ...Read more