Doctor insights on:
Can Multiple Myeloma Affect The Liver
Yes. Not common.: Yes. Multiple myeloma can effect any organ. However, liver involvement is not common. Myeloma generally involves the bones predominantly; however there are reports of nearly every organ being involved in including the brain. Liver involvement by any cancer can make some types of chemotherapy (that is processed by the liver) more difficult to give. ...Read moreSee 1 more doctor answer
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Not that I am aware: Myopathies are disorders of muscle tissues or muscles. I am not aware of a myopathy that will affect the liver specifically. Myopathy may mean that the patient is taking drugs for pain relief that will affect the liver and one must not forget alcohol that if taken at the same time in excess for pain relief will affect the liver. ...Read more
Are there any diseases that can cause lesions on multiple organs (liver,brain,pancreas,etc) besides metastatic cancer?
Central nervous only: Affects brain, spinal cord, and eyes, by attacking the myelin coverings of the nerves. Causes changes in vision, balance, strength, sensation, stamina, memory, bowel and bladder functions, in part. No direct effect on internal organs such as heart or lung. ...Read moreSee 2 more doctor answers
What are the predisposing factors that can transform or activate the chronic hepatitis b virus to lead for cirrhosis, liver failure, hepato cancer .. ?
Not clearly known: It is quite unpredictable what leads the virus to do most of the damage to the liver. So best one can do is avoid any other hepato-toxins like alcohol use . Aslo eat healthy and avoid fatty liver which accompanies over eating and execessive weight. Eat healthy which is to consume low sugared foods with ample amounts of fruits and veggies with each meal. ...Read more
ESLD manifestations: No system of the body is spared in the syndrome of cirrhosis with end-stage liver disease (esld). Will see general deterioration, endocrine problems, cardiovascular, GI (diarrhea, gastropathy) pancreatic-biliary, neurologic, hematologic (coagulopathy ; bone marrow abnormalities), lung (hepatopulmonary), kidney (hepatorenal), lymphatic, dermatologic, musculoskeletal, ;higher risks of cancer. ...Read more
Which STI's other than the obvious hepatitis family can affect the liver and cause deranged transaminases ?
Besides the overexpression of cox-2, what other enzymes/proteins/molecules can create radiotherapy failure (radioresistance) in hnscc stage 1 tumors?
No simple answers: If you are seeking scientific answers to your question, you will need to go to library and spend a few hours reading and learning. We do not have enough space in this column to address such complex issues. ...Read more
How and why is there an increase in urobilinogen levels in hepatocellular dysfunctions like alcoholic liver disease, cirrhosis and malignancy of liver?
Obstruction: When the liver is prevented from doing it's job due to disease it shows itself through elevation of certain chemicals in the blood because it is being blocked by physical disruption of the anatomy and bile goes into the blood causing yellowing of the skin ( jaundice). ...Read moreSee 1 more doctor answer
I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
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