Doctor insights on:
Can Mold Cause Leukemia
Leukemia suggested..: By symptoms and signs: fatigue, pallor, headache, fast heart rat, bleeding, bruising, petechial rash, fever, bone pain, walk refusal or loss of milestones, cranial nerve palsies, lymphadenopathy, splenomegally, etc. While we know much about the molecular genetic events that correlate with and support leukemia, we know little (beyond radiation) as to what causes leukemia. We learn more every day. ...Read more
Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Leukemia cause: We don't know for sure. Leukemia develops as the consequence of a series of genetic changes in blood cell offsprings. These changes alter normal growth and differentiation of the cells, resulting in an accumulation of abnormal, immature blood cells in the bone marrow and peripheral blood. Exposure to chemicals, radiation, tobacco, or chemotherapy, infection, etc have been associated with leukemia. ...Read more
Random mutations...: occur in our body's cells because they are not able to correct all of the millions of DNA damage events that naturally occur during our life. In the event that a bone marrow progenitor cell gets hit with an unlucky series of mutations then a leukemic cell will be made, and grow out of control. Familial susceptibility, or exposures (e.g. chemotherapy, radiation, or benzene) may increase this risk. ...Read more
See below...: Exposure to certain chemicals like benzene or formaldehyde may increase the risk for cancer including leukemia. This is probably due to the mutagenic effect of these agents, meaning they can induce mutations in otherwise normal cells resulting in abnormal cells that can become cancerous; however, the process is usually multifactorial and other conditions need to be met to develop cancer. ...Read moreSee 1 more doctor answer
Rarely causes pain: It is uncommon to have pain as a symptom of leukemia. But if you have it then it is likely to be from the bones, most often from the pelvic/low back area. But you should know what type of leukemia you are dealing with(?) as there are 4 different types which can be either acute or chronic leukemia, with entirely different symptoms from one to the other(s). ...Read more
The cell cycle: ...is activated in the immature "blast" cells of acute leukemia. This is not so much a defect, as it is also a normal attribute of immature blood cells. A major problem is the lack of maturation of these cells into normal non-dividing blood cells. Various transcription factors are mutated and these may cause increased proliferation. CLL is characterized by decreased apoptosis (cell death). ...Read more
No: Dr. Legha is right but has understated matters. After forty years of hype, there's still no reason to think these cause cancer other than some bad studies based on patient and family recall -- you can get ANY "scare story" you want that way. I'd be angry with the people who gave you this disinformation. ...Read moreSee 1 more doctor answer
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