Doctor insights on:
Can Men With Sickle Cell Disease Have Children
Yes.: Sickle cell disease must be inherited from both parents. So it depends on the mother of the child. If she has sickle cell - all of your children will have sickle cell. If she has sickle cell trait - there is a 50% chance your children will have sickle cell disease, and a 50% chance of your children having sickle cell trait. If she has no sickle cell - your children will have sickle cell trait. ...Read moreSee 1 more doctor answer
My husband and I are both carriers of sickle cell anemia. What are our chances of our children exhibiting this disease?
25%: If both of you have sickle cell trait then each of you has one normal beta hemoglobin gene (a) and one with the sickle cell mutation (s). Your children will inherit one beta globin gene from each of you for a total of two. Therefore for each child that you have, there is a 25% chance of sickle cell disease (ss), a 50% chance sickle cell trait (as), and 25% chance of normal hemoglobin (aa). ...Read moreSee 1 more doctor answer
YES: Be sure to let your obstetrician know you have sickle cell so you can be managed correctly. ...Read more
Yes, on average: Due to their disease, sickle cell disease children are immune-compromised, and it will be easier for them to get sick. That is why preventive antibiotics, vaccines, and flu-shots are so important for them. Any fever can represent a life-threatening emergency for them, so they must be extra careful to avoid ill people, wash their hands, avoid crowds, etc. ...Read moreSee 2 more doctor answers
Both carriers of the sickle-cell disease, would you take this risk or decide not to have children?
Personal choice: People decide on having kids for a variety of important considerations. The risk of sickle cell for 2 parents with trait is a firm 25% for any pregnancy, 50% for passing trait, 25% for normal. Ss disease is chronic, painful & frought with medical issues for a reduced life expectancy. That said, the choice remains personal. Donor sperm from a fertility center could avoid part of the worry. ...Read moreSee 1 more doctor answer
Proper care needed: As long as they are under proper medical attention there should be no problem. ...Read more