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Doctor insights on: Can Men With Sickle Cell Disease Have Children

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Can men with sickle cell disease have children?

Can men with sickle cell disease have children?

Yes: Yes, it's possible, though many men with sickle cell have problems with infertility. ...Read more

Men (Definition)

Men are adult members of the male sex. The acropnym men also stands for multiple endocrine neoplasia, a hereditary condition that involves benign and malignant tumors of various glands. There are two main types, men ...Read more


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Can men with sickle cell disease have healthy children?

Can men with sickle cell disease have healthy children?

Yes.: Sickle cell disease must be inherited from both parents. So it depends on the mother of the child.
If she has sickle cell - all of your children will have sickle cell.
If she has sickle cell trait - there is a 50% chance your children will have sickle cell disease, and a 50% chance of your children having sickle cell trait.
If she has no sickle cell - your children will have sickle cell trait. ...Read more

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My husband and I are both carriers of sickle cell anemia. What are our chances of our children exhibiting this disease?

My husband and I are both carriers of sickle cell anemia. What are our chances of our children exhibiting this disease?

25%: If both of you have sickle cell trait then each of you has one normal beta hemoglobin gene (a) and one with the sickle cell mutation (s). Your children will inherit one beta globin gene from each of you for a total of two. Therefore for each child that you have, there is a 25% chance of sickle cell disease (ss), a 50% chance sickle cell trait (as), and 25% chance of normal hemoglobin (aa). ...Read more

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Can people with sickle cell disease have children?

Can people with sickle cell disease have children?

YES: Be sure to let your obstetrician know you have sickle cell so you can be managed correctly. ...Read more

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Will a child with sickle cell disease get sick more often than normal children?

Will a child with sickle cell disease get sick more often than normal children?

Yes, on average: Due to their disease, sickle cell disease children are immune-compromised, and it will be easier for them to get sick. That is why preventive antibiotics, vaccines, and flu-shots are so important for them. Any fever can represent a life-threatening emergency for them, so they must be extra careful to avoid ill people, wash their hands, avoid crowds, etc. ...Read more

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Both carriers of the sickle-cell disease, would you take this risk or decide not to have children?

Both carriers of the sickle-cell disease, would you take this risk or decide not to have children?

Personal choice: People decide on having kids for a variety of important considerations. The risk of sickle cell for 2 parents with trait is a firm 25% for any pregnancy, 50% for passing trait, 25% for normal. Ss disease is chronic, painful & frought with medical issues for a reduced life expectancy. That said, the choice remains personal. Donor sperm from a fertility center could avoid part of the worry. ...Read more

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How many children are born with sickle cell disease a year?

How many children are born with sickle cell disease a year?

1000 in the US: But it is estimated to be 500000 babies worldwide. ...Read more

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How many children are born with sickle cell disease each year?

Aproximately 1600: The sickle cell gene is carried without symptoms in 1/12 african americans. The estimated ss birth rate is 1600 according to the georgia comprehensive sickle cell center at emory university in atlanta. ...Read more

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Does anybody know about how much of children or infants die of sickle cell disease before reaching puberty?

Does anybody know about how much of children or infants die of sickle cell disease before reaching puberty?

Small: With the advancement of preventive care, high utilization of hydroxyurea, and aggressive treatment for the complications associated with sickel cell disease, the life expectancy has greatly increased. According to recent reports, the median age at death for individuals with scd was 42 years for men and 48 years for women. ...Read more

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Can hydrea (hydroxyurea) be used to help children with sickle cell disease?

Can hydrea (hydroxyurea) be used to help children with sickle cell disease?

Yes: In the treatment of sickle-cell disease, hydroxycarbamide increases the concentration of fetal hemoglobin. The precise mechanism of action is not yet clearbut it seems to activate of gammaglobin synthesis necessary for fetal hemoglobin. This stops the rapidly growing cells that turn into sickle cells. ...Read more

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Could hydrea (hydroxyurea) possibly help children with sickle cell disease?

Could hydrea (hydroxyurea) possibly help children with sickle cell disease?

Yes: Hydre increases a type of hemoglobin called fetal hemoglobin in sicle cell patients and this prevents the sickle cells from breaking up easily. Hydrea (hydroxyurea) can reduce need for transfusions and patients may have less pain crises, chest sydrome and other complications. ...Read more

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What are the odds of children born with sickle cell disease living to a ripe old age?

What are the odds of children born with sickle cell disease living to a ripe old age?

Good: With comprehensive sickle cell care, including newborn screening for the disease, childhood penicillin prophylaxis and receipt of new conjugated vaccines to decrease early death from infection, and ongoing screening for increased risk of stroke in childhood with resulting intervention to decrease risk of stroke, it is unusual for a child to die of sickle cell disease today. ...Read more

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Is there a developmental delay in children with sickle cell disease?

Is there a developmental delay in children with sickle cell disease?

Possible: In childhood, 25 percent of children with sickle cell anemia have silent ischemic lesions that may impair neurocognitive function. ...Read more

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Could you tell me if my boyfriend has sickle cell trait does that mean our children could get the disorder?

Could you tell me if my boyfriend has sickle cell trait does that mean our children could get the disorder?

No, if you don't...: If your boyfriend has trait (one beta-hemoglobin gene normal and one with the sickle mutation), and you do not have trait, than your child has a 50% chance of either having trait or having two normal copies of the beta-hemoglobin gene. ...Read more

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How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

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What are some of the more subtle symptoms of sickle cell anemia disease?

What are some of the more subtle symptoms of sickle cell anemia disease?

Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more

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How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it takes 2 sickle genes to cause disease, one gene comes from each parent. Many parents carry this gene quietly, unknown to them because it doesn't make a single gene carrier sick. ...Read more

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How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read more

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Is it possible to be diagnosed with sickle cell anemia at 43? Even without ever experiencing any symptoms of the disease?

Is it possible to be diagnosed with sickle cell anemia at 43? Even without ever experiencing any symptoms of the disease?

Possible, but...: Most people will have symptoms of enough severity to be diagnosed before adulthood. That being said, there is variation in the severity of sickle cell disease, most likely due to a number of other genes that modulate the symptoms. Thus, it probable is quite rare, but there could be that individual with a particular genetic makeup that has minimal disease that goes undiagnosed. ...Read more

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Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?

Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?

In theory 25%: Please remember these statistics apply to large population and therefore it is possible for a couple with sickle cell trait have children with and without sickle cell disease. ...Read more

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If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more

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Does sickle cell nemia has treatment? If so what are the medications? What are the foods that achild with sickle cell anemia eat? Is it tur that when some body reaches the age eighteen the disease disapears

Does sickle cell nemia has treatment? If so what are the medications? What are the foods that achild with sickle cell anemia eat? Is it tur that when some body reaches the age eighteen the disease disapears

Many questions: Sickle cell anemia is genetic and never disappears without bone marrow transplantation. Sickle cell anemia has medications that improve outcomes. Penicillin prophylaxis, empiric treatment of fever with antibiotics, and Prevnar (pneumococcal vaccine) / Pneumovax immunizations decrease risk of dying from infection. Hydroxyurea can decrease the frequency of painful crises and may minimize / delay sickle cell damage to body ...Read more

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Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Agree with Dr Diede: Sickle-cell trait & disease is an autosomal recessive inheritance from parents (genetics). Malaria is a parasitic infection. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life." ...Read more

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My boyfriend & I have sickle cell anemia, our son will also inherit the disease. Should we wait until umbilical cord stops pulsating before clamping?

Doesn't matter: Sickle cell disease will affect his blood cells over time as they sickle with dehydration and illness, or as they live a shorter duration in the body. Generally there aren't any symptoms at birth, and nothing having to do with the cord will make a difference. In actuality, his fetal hemoglobin will be more protective from sickle cell, and treatments now focus on keeping fetal hemoglobin around. ...Read more

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What kind of disorder is sickle cell anemia?

What kind of disorder is sickle cell anemia?

Genetic: With ss disease a genetic mutation changes the gene sequencing needed for normal hemoglobin production. The alteration changes the way the hemoglobin handles the oxygen molecule as it carries it in the blood. The blood cell then becomes distorted in the small capillaries and the spleen. The cell breaks down rapidly and or remains trapped.Anemia is a chronic problem. ...Read more

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If you have sickle cell anemia, what are the chances you'll pass it on to your children?

If you have sickle cell anemia, what are the chances you'll pass it on to your children?

Depends: If your partner does not carry the gene, all your babies would be carriers. If your partner is a carrier, the risk is 50% with any pregnancy. ...Read more

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What are symptoms of sickle cell anemia in school children?

What are symptoms of sickle cell anemia in school children?

Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more

Dr. James Ball
355 Doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more


Male (Definition)

Male refers to the masculine gender, those people ...Read more