Doctor insights on:
Can Lyme Effect Bone Marrow Levels
I've been told that I have Lymes disease in my bones due to not be caught in time. I moved to different city. Have new Dr an am told I don't have lyme?
An Infectious: Disease specialist can give u the definitive answer. Get your lab tests together and go for a consult. It IS important to know. It determines treatment and outcome. Let us know what happens. ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
Bone arrow biopsy: The bones are covered with a tissue called periosteum which has pain nerve fibres and is very sensitive to any injury. The doctor should numb the skin as well as this deeper layer. The needle is large but proper numbing would eliminate most of the pain. Once the numbing wears off, pain returns in a few hours but should be tolerable. Ice or tylenol (acetaminophen) will be helpful. ...Read more
What are some good concrete metrics in defining remission for waldenstrom's macroglobulinemia — in terms of bone marrow analysis and IgM level?
50%, 90%, 100%:
Con?rmation of response in wm has been
adopted from response criteria for multiple
myeloma. See http://www.Iwmf. Com/docs/ghobrial_clincial_trials. Pdf
especially see tables xi, xii. The treatment of wm is aimed at control of symptomatic disease. Risk/benefits of various therapies are highly individualized based on patient and disease characteristics. ...Read more
Chronic osteomylitis, bone marrow biopsy normal, jak-2 mutation negative, erythropoitin level normal, s. Ferritin level 5 but hb.17.8. What is its reason?
Many possibilities: Your question is why your hemoglobin is at the top-of-normal (or maybe a tiny bit above) for a person of your age and gender. I'm much, much more concerned about your chronic osteomyelitis. I'd consider a right-to-left cardiac shunt, osler-weber-rendu lung shunt, sleep apnea, high-affinity hemoglobin, an obscure mutation. It's not dangerous in itself & could "just be you.". ...Read more
Could my leg pain be a symptom of my chronic Lyme? My bone feels like it will snap in one spot w/ pressure on it. I also used to be on depo provera (medroxyprogesterone)
Thoughts: Your pain does not seem consistent with either chronic Lyme (although chronic Lyme has several non-specific possible presenting symptoms) nor Depo use. However, it sounds pretty extreme and you need a physical exam and some tests to rule out some bone problems that may be more common in young women. ...Read more
Joint pain everywhere, bone pain in forearm and shines, can't move at times, muscle weakness, numbness fingers toes. RA is -, lupus- lyme-, what else?
See details: Have you seen a rheumatologist? If not, see one asap. ...Read more
Diff. Swallowing, joint n bone pain, muscle spasm, toes n fingers numb. Severe pain I cry! N can't move, ra-, lupus-thyroid-lyme-, tramadol no help?
Register as a Donor: You can register in any blood bank by asking about the national marrow donor program(nmdp) also called: be the match registry. It is simple to register as a potential donor by giving a sample of body cells, usually taken from inside of your cheek. Once they find your body cells match someone in need they will call you to donate your blood stem cells or marrow stem cells. ...Read more
Bone marrow tests are performed for many reasons, but the commonest ones are:
detecting bone marrow involvement by a cancer — many cancers, notably lymphomas spread from their primary site to different organs of the body, including the bone marrow
detecting cancers of the blood leukemias finding the cause of anemia.
Bone marrow infiltration by other diseases ...Read more
HLA type: Every cell in your body has human leukocyte antigens (hlas) on the surface that act like a cell i.D. These allow your immune cells to recognize your cells as part of you and not foreign cells that need to be attacked. The bone marrow donor's hlas should match the patient's hlas as closely as possible so the donor's immune system doesn't attack the patient! Hla is determined by a blood test. ...Read more
No: This can seem confusing. Bone marrow contains stem cells that reproduce and generate blood cells throughout life. These stem cells are what are transferred in a bone marrow transplant and cause normal blood cells to be produced in the recipient. These are different from germ cells (eggs and sperm) that come together to cause a pregnancy. They are not interchangeable. ...Read more
See below: Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately 2.6 kilograms (5.7 lb). ...Read more
It depends: Chances of you being a match are low but real. So be prepared to keep your commitment in case you receive a call to be the real donor because they have someone whose hla typing matches yours... The chances are less than one in a thousand unless you are blood related with the donor. ...Read more
It requires Tissue t: It requires fairly sophisticated lab tests to do the tissue typing and matching between the donor cells and the recipient. It is called hla(human leukocyte antigen) typing which is done from body cells(usually taken from a cheek swab) of the donor. Blood cells(white cells) are a common cell type used as the tissue antigens/proteins are commonly expressed on the white cells. ...Read more
It depends: If done by an experienced health care worker(doctor/nurse) the bone marrow biopsy can be tolerable(mild to moderate amount of pain). They use local anesthesia which controls 90% of the pain. So I would not worry too much about it and get it done. Just make sure that the person doing the biopsy has done more than 20 biopsies before and does them fairly frequently(>1 per month). ...Read more
Saves lives: Pros far outweigh the cons. You can save lives and provide an amazing gift to a very sick person by this selfless act of kindness. Minor chance of infection, and can be a little painful. ...Read more
A condition caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu-like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnoses are not very reliable, and sometimes clinical ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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