Doctor insights on:
Can Lupus Erythematosis Be Misdiagnosed For Polymorphous Light Eruption
Lupus: Lupus can be associated with internal problems including problems with the kidneys, sores in the mouth, hair loss and other issues. Pmle involves the skin only and resolves relatively easily with topical steroid use and can be controlled with sunscreen use. Lupus can progress over time and should be monitored closely by a physician for signs of progression.
Autoimmune: Lupus is an autoimmune condition in which antibodies are made against your own body. Sun can trigger a flareup of rashes associated with lupus. Pmle on the otherhand is a variable rash on sun exposed areas such as the arms and chest that occurs early in the sunny season of the year. This does not have autoantibodies associated with it. These can be distinguished via blood work and a skin biopsy.
Hello, I have polymorphous light eruption and was wondering if I take Claritin (loratadine) daily if that would be unhealthy on my body to prevent an outbreak?
PMLE: If your pmle is severe, your dermatologist may recomend one of the following: short course of oral steroids e.g. To cover a summer holiday. Polypodium leucotomas (heliocare™) beta carotene. Hydroxychloroquine. Uvb or puva - a special form of ultraviolet treatment for several weeks in early spring. Antihistamines: oral antihistamines like Diphenhydramine (bendaryl®) have been used to treat hives an.See 1 more doctor answer
I have hypothyroidism and now I have polymorphous light eruption and I've been told the 2 can be linked i'd like th know how they are?
Both autoimmune?: I found one article (indian journal of dermatology 76:6, nov-dec 2010, pp. 704-5) reporting that patients who have pmle in guntur (a city in central india) are 3 times more likely to have hypothyroidism than those who don't. They speculated that the immune dysfunction that causes pmle may also be causing antibody generation in thyroid disease. Clearly, more research is needed.
I have polymorphous light eruption (PMLE) I was wondering if someone could give me some ideas for the sever itching I itch most at night while asleep.
Pmle: Try taking a bath in colloidal oatmeal before bedtime
Thin skin: Thin area around the nose/cheeks is very sensitive to sun and the first to show sle signs.
I was diagnosed with ra. Recently, I have been showing the symptoms of lupus. Minus the butterfly rash. Is it possible that I was misdiagnosed?
Is pmle similar to lupus photosensitivity rash? Have positive ANA and dsdna with joint pain. Thought this was always sun rash...Lupus?
Yes: It could be a lupus rash especially with your positive lab results.
PMLE: The exact cause of polymorphous light eruption isn't well understood. The rash appears in people who have developed a sensitivity to ultraviolet (uv) radiation from the sun or other sources, such as tanning beds or tanning lamps. This sensitivity results in sunlight-induced immune system activity that produces inflammation and a rash. No patients with pmle have progressed to lupus.
Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis.
Labs, imaging, biopsy: Lupus and sarcoidosis affects many organs and both can have similar symptoms. However doctor (rheumatologist) can differentiate these two diseases by various blood tests, imaging and sometimes biopsy - skin, liver and kidney depending on the organ involved. So the diagnosis is often clear, raraly misdiagnosed. The diagnosis must be confirmed as the treatment options are quite different.
Systemic lupus/teens: Yes it can appear in teens.Get a more detailed answer ›
See rheumatologist: It is critical to see a rheumatologist, who can determine if it is lupus, if it actually compromises your health, what body systems are affected and if treatment is needed, to tailor the treatment to the risks they present.See 1 more doctor answer
SLE: Lupus erythematosus is a name given to a collection of autoimmune diseases, in which the human immune system becomes hyperactive and attacks normal, healthy tissues. Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.See 1 more doctor answer
Probably not: Since your genes may well render the baby at a higher risk of developing an autoimmune disease, I'd prefer that you don't. However it would be a different matter if you decide to have a child of your own due to your own needs but your eggs would not be ideal as donor eggs. I am not a genetic counsellor but why take the risk?
It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all.
Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers.See 1 more doctor answer
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