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Doctor insights on: Can Lupus Damage Your Liver

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Can lupus cause liver scarring?

Can lupus cause liver scarring?

No: Lupus is unlikely to involve the liver. If you have significant liver disease and a positive ANA look for other causes such as viral or autoimmune hepatitis. ...Read more

Dr. Arthur Balin
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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What can cause kidney and liver damage?

What can cause kidney and liver damage?

Broad question: Damage to liver by alcohol, hepatitis infections/drugs can affect kidney function. Certain disease like lupus, sarcoidosis, cystic disease , Wilson disease, can affect both organs.The list is long.. Need a specialist to evaluate the cause ...Read more

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What pain meds can be taken with liver disease without causing more liver damage?

What pain meds can be taken with liver disease without causing more liver damage?

Ask your doctor: There many types of "liver disease." you have to ask your gi/liver doctor what meds are best/worst for you. Your doctor will be able to give you a very clear list. ...Read more

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Can diabetes cause your liver enzyme to be elevated?

Can diabetes cause your liver enzyme to be elevated?

Yes: 1. Poor control causes abnormal lipid/cholesterol pattern 2. Diabetes associated with genetic abnormalities in cholesterol combination increase risk of fatty liver, hepatitis, even liver failure must treat diabetes and cholesterol agresssively and it can all be prevented. ...Read more

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How many acetaminophen would cause liver damage?

How many acetaminophen would cause liver damage?

Eight plus: Most Acetaminophen pills are 500 mg. The generally accepted rule of thumb is that more than 4 grams (4000 mg) is likely to injure the liver. Thus a person should not exceed eight Acetaminophen pills per day. Less is even better. ...Read more

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How does cyclosporine damage your kidney tissue?

How does cyclosporine damage your kidney tissue?

Renal tubular damage: Cyclosporine is an immune supressing medication used for renal transplant patients. Overtime, this potent medication especially when its levels are high can damage the tubular structure of the kidney. If you are concerned about its use, discuss this issue with your nephrologists or your transplant team. ...Read more

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Can Valium damage liver? And if so, how significant can the damage be?

Can Valium damage liver? And if so, how significant can the damage be?

Unlikely but possibl: Valium is metabolized by the liver and like any drug broken down by liver enzymes it can cause some stress but it is unlikely that it will lead to much actual injury to the liver. ...Read more

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Can vascular conditions cause liver damage?

Can vascular conditions cause liver damage?

Depends: If the vascular damage is in the abdomen and leads to the kidney the answer would be yes. It is individual and hard to tell for certain. ...Read more

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Does liver damage and disease always involve high or abnormal liver enzymes?

Does liver damage and disease always involve high or abnormal liver enzymes?

No: You can have chronic hepatitis B or C with normal liver enzymes. You can also have other chronic liver conditions, such as cirrhosis of the liver, with normal liver enzymes. ...Read more

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What can cause liver damage?

What can cause liver damage?

Many causes.: there are entire text books written on possible causes of liver damage. The most common causes in the United States are alcohol, viruses, medications, genetic, and autoimmune processes. Each of these can damage the liver in various ways. If you feel you have liver damage, see your doctor. They may recommend that you see a gastroenterologist also. Good luck. ...Read more

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How can liver cirrhosis and liver cancer be differenciated???

How can liver cirrhosis and liver cancer be differenciated???

Cirrhotic at risk: liver cancer usually happens in a cirrhotic liver. cirrhosis = scarring of the liver, cancer = uncontrolled cell growth. if you really have cirrhosis, you need to be screened for cancer regularly (can happen in 1-3% of cirrhotics per year) ...Read more

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Which vitamin level can be related to liver damage?

Which vitamin level can be related to liver damage?

Vitamin A: is something we can OD on and can be toxic to the liver. A lot of vitamin A is found in cod liver oil. Use Marine Fish Oil instead. Peace and good health. ...Read more

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How can diabetes damage the kidneys?

How can diabetes damage the kidneys?

High glucose: Diabetes hurts the blood vessels due to by products of high glucose. The first vessels to get affected are micro vessels. All organs in body have micro vessels. The organs that rely on micro vessels for function are kidneys, eyes, heart, nerves. This is why these organs are hurt by by diabetes. ...Read more

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What can help the liver damage?

What can help the liver damage?

Remove insult: It is difficult to help liver damage, other than removing the insulting agent wether that be a toxin (drug or alcohol) or virus. Vit e has shown some benefit in helping damage done with fatty liver disease, however there is new concern about increasing prostate cancer risk with its use. No herbal medication has consistently proven any benefit. ...Read more

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Can controlled diabetes damage your kidney, eye or heart?

Can controlled diabetes damage your kidney, eye or heart?

Yes: Diabetes can damage several organs even if diabetes is strictly controlled. However the complications are delayed for several years and are easier to manage. It is prudent to visit your primary care physician on a regular basis so that diabetic complications can be detected at early stage. ...Read more

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Can scoliosis damage any of your organs?

Can scoliosis damage any of your organs?

Only extreme: Yes, but this is only seen in extreme scoliosis where the lungs and heart can become compressed. This is for the extremely bad cases only and not common in otherwise healthy people. ...Read more

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How common is liver problems with lupus?

How common is liver problems with lupus?

Very uncommon: Liver disease is not a component of lupus but one can have a positive ANA in autoimmune hepatitis. ...Read more

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Lupus fatty liver advice please?

Lupus fatty liver advice please?

Perhaps: Lupus can be dangerous depending on its severity. Lupus and fatty liver aren't really related. Fatty liver is usually related to alcohol consumption or the metabolic syndrome (diabetes, obesity, high cholesterol, high blood pressure). Fatty liver with inflammation can lead to cirrhosis, generally takes decades to occur. Lupus is an autoimmune disease and their are autoimmune liver diseases too. ...Read more

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Can lupus cause liver scarring?

No: Lupus is unlikely to involve the liver. If you have significant liver disease and a positive ANA look for other causes such as viral or autoimmune hepatitis. ...Read more

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Lupus and fatty liver is it dangerous?

Lupus and fatty liver is it dangerous?

Perhaps: Lupus can be dangerous depending on its severity. Lupus and fatty liver aren't really related. Fatty liver is usually related to alcohol consumption or the metabolic syndrome (diabetes, obesity, high cholesterol, high blood pressure). Fatty liver with inflammation can lead to cirrhosis, generally takes decades to occur. Lupus is an autoimmune disease and their are autoimmune liver diseases too. ...Read more

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Can lupus cause non-alcoholic fatty liver?

Can lupus cause non-alcoholic fatty liver?

Autoimmune hepatitis: Lupus is associated with autoimmune hepatitis, not nash (non-alcoholic fatty liver). Nash is commonly see in settings of obesity, excessive alcohol intake, diabetes, high cholesterol. Both entities can occur together when respective risk factors for both exist. ...Read more

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How much does liver damage, excessive pain medication, lupus, and previous miscarriages increase chances of a future occurrence?

Definite risk: Any miscarriage with sle increases the chance of another miscarriage. So do other pregnancy related problems. You should see a rheumatologist and a high risk obstetrician with sle experience and discuss the timing and risks of oregnancy for your individual problems. ...Read more

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I have lupus sle. I have a fatty liver I have been told. what does this mean?

Hepatic steatosis: or fatty liver disease,...is a reversible condition wherein large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e., abnormal retention of lipids within a cell). Diet and weight loss can help this condition. ...Read more

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Will a liver transplant be affected by my lupus?

Will a liver transplant be affected by my lupus?

My help: It is unclear whether systemic lupus erythematosus (SLE) is the cause of your liver disease. Liver involvement requiring liver transplantation is a rare complication of SLE, although there are specific issues related to SLE, in general, SLE activity is milder or controlled after transplant. SLE is an autoimmune disorder and the drugs used to treat SLE are often ones used to prevent rejection ...Read more

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I was recent diagnosed witj lupus which is attacking my liver and kidneys. Is methotrexate safe to take if my liver is already messed up?

I was recent diagnosed witj lupus which is attacking my liver and kidneys. Is methotrexate safe to take if my liver is already messed up?

Possibly not safe: Mtx should be avoided in active liver injury. It should also be avoided if you have abnormal renal function as it can accumulate in blood and cause increased toxicity. Would recommend discussing these issues with your rheumatologist. ...Read more

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Have Lupus and Parkinson's and just found out I have a fatty liver is there a reverse on fixing it? If not how fast does it progress into failure?

Have Lupus and Parkinson's and just found out I have a fatty liver is there a reverse on fixing it? If not how fast does it progress into failure?

Heterogenous.: Fatty liver is very difficult to predict but generally carries a pretty good prognosis - very very slowly progressive. Of course do need to prevent any other liver disease by restricting known toxins (alcohol and tylenol) and by getting vaccinated against hepatitis A and B. ...Read more

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Can arava (leflunomide) be prescribed for lupus? What is the best medication for sle lupus when liver and kidneys are affected? Thank you very much.

Not really: In my experience it has little or no value. The liver is not involved in lupus so look for other causes. With renal disease, a biopsy is essentially and CellCept (mycophenolate mofetil) would be the drug of choice. ...Read more

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Lupus, fibro, gastroparesis, non alcholic fatty liver, diverticulosus/itis don't normally drink but I drank alot the other night and really sick since?

Lupus, fibro, gastroparesis, non alcholic fatty liver, diverticulosus/itis don't normally drink but I drank alot the other night and really sick since?

Need exam,blood test: I would suggest you have an exam, and perhaps a blood test of the liver enzymes to see if the liver is inflamed. Sometimes lupus can affect the pancreas as well, and this plus alcohol together would mean the pancreas blood test should be checked too. A good examination is important, and if you are having fever, dark urine, chalk colored stools or severe abdominal pain make sure you are seen soon. ...Read more

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Have lupus. Being tested for possible autoimmune liver diseases. Recent blood work showed immunoglobulin M elevated at 470 (range 26-217). ?

Have lupus. Being tested for possible autoimmune liver diseases. Recent blood work showed immunoglobulin M elevated at 470 (range 26-217). ?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, a single test like slightly elevated IgM is not meaningful. Lupus is a complicated illness and the individual needs to be treated, not a lab test result. Wish you good health. ...Read more

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Positive ANA twice from 2 different labs. Not lupus or RA. High liver test. 24 years old, normal weight. Suggestions on what I should test for next?

Positive ANA twice from 2 different labs. Not lupus or RA. High liver test. 24 years old, normal weight. Suggestions on what I should test for next?

Concern: You'll want to find out whether you have autoimmune hepatitis, what we used to miscall "lupoid hepatitis". It's very serious but can often be managed. Your next test will be anti-smooth muscle / anti-actin and perhaps anti-LKM. ...Read more

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Methotrexate :The most common adverse effects include: hepatotoxicity (liver damage),but could this be seen in low dose for Lupus affecting skin ?

Methotrexate :The most common adverse effects include: hepatotoxicity (liver damage),but could this be seen in low dose
for Lupus affecting skin ?

Yes: Toxicity to liver, kidney, intestine, bone marrow, etc., is related to dosing and duration of exposure. Must not drink alcohol. Dosed once a week. Daily folic acid reduces toxicity. Various treatments exist for discoid lupus. Protect from sun. ...Read more

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Just diagnosed w/lupus.Only symptom I have is muscle & joint pain.Blood tests say kidney & liver functions normal.Can I eventually get other symptoms?

Just diagnosed w/lupus.Only symptom I have is muscle & joint pain.Blood tests say kidney & liver functions normal.Can I eventually get other symptoms?

Yes: The most likely time to develop kidney disease or more serious issues is within the first 4 years of the diagnosis. That is why you need prriodic lab studies and should be under the care of a rheumatologist. ...Read more