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Doctor insights on: Can Long Term Use Of Hyzaar Cause Permanent Swelling In Legs

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Can long term use of hyzaar (losartan and hydrocholorthiazide) cause permanent swelling in legs?

Can long term use of hyzaar (losartan and hydrocholorthiazide) cause permanent swelling in legs?

Not from Hyzaar (losartan and hydrocholorthiazide): Hyzaar (losartan and hydrocholorthiazide) is a combination of a diuretic/water pill and an angiotensin receptor blocker/arb which is used to lower blood pressure. The constant leg swelling may mean you are retaining fluid and need a higher dose of diuretic. The arb component has a 1-3% chance of causing angioedema, episodes of swelling involving various parts of the body (unusual to only affect legs) for 24-72 hr not constantly. ...Read more

Lower Leg Swelling (Definition)

Is it one leg or both? Has there been recent trauma? The definition is enlargement of the lower leg. Could be superficial fluid accumulation or it could edema (swelling) of one or both of the muscles of the lower leg: the gastrecnemious and the soleous muscles. Internet consult not enough, see ...Read more


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What are the long term effects of methadone use. 10+ years or more. Can it cause dementia?

What are the long term effects of methadone use. 10+ years or more.  Can it cause dementia?

NO: Methadone can be associated with a number of side effects, but actually very few long-term "organ" effects (heart, liver, kidney, brain etc.) constipation, increased sweating, hormonal changes that alter libido, erectile function and fertility. Weight gain with its attendant problems certainly can occur. Heart rhythm problems, although getting publicity, are rare. Think about alcohol;tobacco use. ...Read more

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Can cutting in the same spot over and over cause any serious long term problems? (besides infection and scarring)

Can cutting in the same spot over and over cause any serious long term problems? (besides infection and scarring)

Why would you???: Unless there is some medical reson for doing this, why would you want to cut over and over again in same place? Please explain? Besides infection and scarring, you coul sustain injuries to deep structures such as nerve, tendon, muscle bone. Furthermore, it could cause adhesions and interfere with function or interrupt blood supply and cause delayed healing. ...Read more

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What are some side effects of avapro (irbesartan)? Can it cause tingling or joint/muscle pain over the long term?

What are some side effects of avapro (irbesartan)? Can it cause tingling or joint/muscle pain over the long term?

See below: Navarro is an angiotensin II inhibitor. It is used for hypertension and diabetic renal disease. Side effects are diarrhea, upset stomach and tiredness. Your symptoms are possible but not common and other causes should be thought of too. ...Read more

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Is it possible for long term ibuprofen use to cause hives and facial swelling?

Is it possible for long term ibuprofen use to cause hives and facial swelling?

Avoid NSAIDs: Chronic idiopathic urticaria (hives) and angioedema (swelling) can be triggered by regular or high doses of NSAIDs like ibuprofen and Aleve. There is evidence to suggest that avoiding aspirin and NSAID's can prevent exacerbation of hives and swelling. Use Tylenol (acetaminophen) as a substitute at low doses. If this fails to control symptoms Celebrex (celecoxib) can be used instead. See Allergist for details. ...Read more

Dr. Alan Ali Dr. Ali
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What are some side effects of atenolol? Can it cause tingling or joint/muscle pain over the long term?

Dr. Alan Ali Dr. Ali
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What are some side effects of atenolol? Can it cause tingling or joint/muscle pain over the long term?

Normalol: Also called atenolol, is a beta-blocker anti-hypertensive medication. Depression is reported as one of its side-effects, depending on dose. Other side-effects might include blurred vision, confusion, dizziness, sweating, wheezing, shortness of breath. ...Read more

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Can short term prednisone use cause damage to an older males kidneys?

Can short term prednisone use cause damage to an older males kidneys?

Should not: Would be extremely rare for this to happen. If u have underlying chronic kidney disease, steroids can cause indirect influences on the kidneys. But again, very rare ...Read more

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Can denture adhesive crean over long term cause or contribute to hardening of the arteries?

Can denture adhesive crean over long term cause or contribute to hardening of the arteries?

No: There is no concern using denture adhesive and cardiovascular disease. Other than the mess and some local gum irritation, it is safe to use. They recently recalled denture adhesives because of the zinc contained in them. There was a connection with a nerve disorder and long term use of adhesives containing zinc. Now they only sell zinc free adhesives. ...Read more

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Are there side effects related to the long term use of omeprazole in 2013?

Are there side effects related to the long term use of omeprazole in 2013?

Nothing serious: There is not much data available. Yet it is a fairly safe drug and can be sued for the long term. But try to skip it for one day off and on. ...Read more

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Can Gabapentin cause severe tingling in the feet as a side effect?

Can Gabapentin cause severe tingling in the feet as a side effect?

Very common SE: Gabapentin may cause tingling and it is a common side effect. As your body adjusts to the medicine during treatment this side effect may go away. If concerned, ask your prescribing physician for more information. ...Read more

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Can long term use of fentanyl patch lead to extreme hypersensitivity after stopping use? Three years of hypersensitive pain that is horrible.

Can long term use of fentanyl patch lead to extreme hypersensitivity after stopping use?  Three years of hypersensitive pain that is horrible.

Fentanyl patches: Long term use of any opioid causes dependence. The hypersensitivity you refer to is opioid induced hyperalgesia - this can be seen and is really dose and time dependent. ...Read more

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How long do side effects of 30 radiotherapies to the head last ie dry mouth, numbness and hearing. Thankyou?

How long do side effects of 30 radiotherapies to the head last ie dry mouth, numbness and hearing. Thankyou?

Depends: The long term effcts of radiating can vary depending on exactly where the radiation was and how much your doctor was able to pinpoint the target. The higher the dosage, the more side effects you will have. These can be long lasting. Work with your dentist and radiologist to minimize the effects and protect you teeth. ...Read more

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What kind of damage can long term waist training cause and would it be permanent?

What kind of damage can long term waist training cause and would it be permanent?

Corset issues...: Think of your body as a balloon like the long ones people make animals out of. If you squeeze and tighten one section, the stuff (air in a balloon, all sorts of stuff in a human) being squeezed must pop out in a different section of the balloon or the body. Where else would all the stuff go? Abdominal muscles are vital to supporting the back and abdomen. A corset interferes with abdominal muscles. ...Read more

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What are long term effects of numbness in lower body caused by severe compromise causng narrowness in the spinal canal?

What are long term  effects of numbness in lower body caused by severe compromise  causng narrowness in the spinal canal?

Many consequences.: The degree of narrowing of the spinal canal and at what level of the spine become paramount in determining prognosis and consequences. ...Read more

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Could the use of PRP ,for hair loss and for many years,provoke long term effects on nervous system?

Could the use of PRP ,for hair loss and for many years,provoke long term effects on nervous system?

Platelet Rich Plasma: Very effective for hair regrowth at this point. No side effects. It's your own blood! Examples: J Cutan Aesthet Surg. 2014 Apr;7(2):107-10. Platelet-rich plasma in androgenic alopecia: myth or an effective tool. Biomed Res Int. 2014;2014:760709. Epub 2014 May 6. The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric.. ...Read more

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After long term use of terbutaline (8 weeks) can the drug leave lasting side effect of tachycardia, shortness of breathe, etc.?

After long term use of terbutaline (8 weeks) can the drug leave lasting side effect of tachycardia, shortness of breathe, etc.?

Yes: Those are short term side effects that usually resolve within minutes. There usually shouldn't be long term side effect per se. ...Read more

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Are the effects of Cerebral Edema from hypotonic solution potentially long-term? Why wouldn't they affect long-term?

Are the effects of Cerebral Edema from hypotonic solution potentially long-term?  Why  wouldn't they affect long-term?

Transient: When the concentration of fluid outside the cell is less than inside the cell, water travels across the cell wall to equalize the concentrations. If hypotonic fluids are given water will enter the cells but when both sides are equal the swelling will then resolve. ...Read more

Dr. David Schleimer
1,498 doctors shared insights

Swelling (Definition)

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more


Dr. Jeffrey Stevens
47 doctors shared insights

Losartan And Hydrocholorthiazide (Definition)

Losartan|hydrocholorthiazide is a combination blood pressure agent which is a kind of blood ...Read more