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Doctor insights on: Can Lack Of Vitamin B12 Cause Macrocytic Hypochromic Anemia

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Dr. Ed Friedlander
279 doctors shared insights

Iron Deficiency Anemia (Definition)

It refers to a low number of red cells in the circulation resulting from a decrease in production in the bone marrow as a result of low amounts of iron available for this purpose. It is the most common type of anemia in the world, commonly due to dietary deficiency, multiple pregnancies, menstrual periods, chronic parasitic infestations, or other causes of chronic bleeding ...Read more


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What are all the causes of moderate macrocytic anemia in elederly other than vitamin B12 and folic acid defficiency. Can severe depression cause that?

What are all the causes of moderate macrocytic anemia in elederly other than vitamin B12 and folic acid defficiency. Can severe depression cause that?

Depression>poor eatg: Anemia should not be accepted as an inevitable consequence of aging. A cause is found in approximately 80 percent of elderly patients. The most common causes of anemia in the elderly are chronic disease and iron deficiency. Vitamin B12 deficiency, folate (folic acid) deficiency, gastrointestinal bleeding and myelodysplastic syndrome are among other causes of anemia in the elderly. Serum ferritin is the most us. ...Read more

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My dad has normal tests of liver and kidneys. Also normal urine test, vitamin b12, heart, mch, wbc, and no tumor. But got macrocytic anemia. Why?

My dad has normal tests of liver and kidneys. Also normal urine test, vitamin b12, heart, mch, wbc, and no tumor. But got macrocytic anemia. Why?

Labs: How high is the MCV and how low is the Hb? A blood B12 can be misleading in come cases, a more definite test is needed, called Methylmalonic acid acid level along with RBC folate level and not just a pure folic acid level. If they are normal. In some cases a Homcystine level may be needed. Best of luck ...Read more

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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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What would cause a vitamin B12 deficiencybesides anemia?

What would cause a vitamin B12 deficiencybesides anemia?

Vitamin B12 def: actually it's the other way around, Vit b12 def causes the anemia. B12 def occurs in people who are vegetarian and don't take vitamin supplement, also malabsorption could lead to B12 def, also there is a condition called pernicious anemia which is an autoimmune disease and these patient cannot absorb b12. ...Read more

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Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more

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How low does ones vitamin B12 level need to be to reach anemia?

Good question: It depends more on how long it is low. The longer the B12 level is low is more important then the level. Hope this helps. ...Read more

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How low does level of vitamin B12 need to be considered deficiency anemia?

Low B12: Values of less than 200 pg/ml are a sign of a vitamin B12 deficiency. People with this deficiency are likely to have or develop symptoms. Older adults with vitamin B12 levels between 200 and 500 pg/ml may also have symptoms. ...Read more

Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


Dr. Randy Baker
973 doctors shared insights

Vitamin B12 (Definition)

Vitamin B12 is a vitamin which is a kind of nutritional agent ...Read more