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Doctor insights on: Can Itp Be Fatal

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Can itp be fatal?

Can itp be fatal?

Can be, but rare: Most people w/ treated itp can expect to live a normal life span. Platelets help the blood clot, so a person w/ extremely low platelets (due to immune system attack in itp) can have fatal bleeding esp in the brain. However, this happens <1% of the time. Your doctor will monitor your platelets, and there are many treatments for itp such as Prednisone that can help maintain a good platelet count. ...Read more

Dr. Steven Ginsberg
127 doctors shared insights

Itp (Definition)

ITP is a bleeding disorder in which platelets are destroyed by the immune system. Platelets are found in the blood and help blood to clot. Common symptoms include abnormal ...Read more


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What are the tests for itp?

What are the tests for itp?

ITP: Thrombocytopenia or low platelet level can be caused by so many things such as drugs, platelet consumption by clots, infections, vitamin deficiency, cancer related etc. Your doctor has to rule out all those possibilities and ultimately to do a bone marrow biopsy to eval bone marrow. See your md and discuss further re-diagnosis approach/treatment and other things you need to know re - itp. ...Read more

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What are the symptoms of itp?

What are the symptoms of itp?

Symptom: Most of the time itp patients are asymptomatic and the only abnormality they have is the low platelet level on their blood counts. They can have bruising, tiny red dots on the skin, roof of the mouth etc- ( ptechiae) or other type of bleeding such as bleeding in the gum , only if platelet level goes down really low-below 30k or so. ...Read more

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What're the main causes of itp?

In the old days....: The "i" in itp stood for idiopathic, which means we didn't know what was causing the problem. We now know this to be an autoimmune process where antibodies recognize proteins on the surface of platelets and target them for destruction by the reticuloendothelial system. Most cases follow an infection (usually viral), but they can also be the presenting feature of autoimmune disorders or malignancy. ...Read more

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What are the corollaries of getting itp?

Bruising, bleeding: People with itp may be at an increased risk of bruising or bleeding, depending on the platelet count and other factors, such as medications. If needed, itp can be treated with steroids or other medications. In some instances, removing the spleen (splenectomy) may be recommended. If you are to require surgery, the surgeon should be made aware of this condition. ...Read more

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What is the mortality rate of itp?

Good: Most patients are able to recover platelet counts and have a mortality rate similar to the general population. For more details see this link. http://bloodjournal.hematologylibrary.org/content/97/9/2549.long. ...Read more

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Is itp one a psychosomatic disease?

Is itp one a psychosomatic disease?

Autoimmune disease: Idiopathic thrombocytopenic purpura (itp) is an autoimmune disease. In this potentially life-threatening disorder self antibodies directed against platelets result in low levels of platelets in the blood. Platelets are necessary for effective blood clotting. People with itp can die from loss of blood after trauma of from a brain hemorrhage. Death is not a psychosomatic disease. ...Read more

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Why can't i give blood if i had itp?

Why can't i give blood if i had itp?

?antibodies: Because if you have antibodies in tyour blood that attack platelets, thaey could be given to the recipient. Also, itp may actuall be another condition, like lymphoma. ...Read more

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What's the mortality rate for people with itp?

It's very rare, but: Does happen. If ones platelet count fall to low enough, spontaneous bleeding can occur. Head bleeds, for example, can be both spontaneous and life-threatening. That being said, the plts that a person with itp does have tend to be more thrombofenic because they are "younger". This helps to mitigate the consequences of low PLT count. Your dr. Can give you additional info. Good luck. ...Read more

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Does anyone knows how effective is rituximav if I have itp?

Response rate 20-30%: Recent review in blood in may 2012 looked at several articles and found a 5-year response rate in adults to be around 26%. Meaning these patients had a sustained elevation of their platelet count for 5 years. Initially the response rate is close to 60%. It is given weekly for 4 weeks. So in summary, it works well. Hope this helps. ...Read more