Doctor insights on:
Invasive Cervical Resorption And Leukemia
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Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Could I have an autoimmune disease, lymphoma, leukemia if i can't fight any vaginal infection&have 2 firm pea sized lumps (cervical node & under chin?
Yes : Lymphadenopathy (swollen lymph nodes) has many causes like some of the things mentioned above. It is best to follow these with you doctor. If they don't get smaller with time and/or antibiotics, then the doctor may recommend a biopsy with either a needle or a surgery to further evaluate what is going on. ...Read moreSee 1 more doctor answer
Rarely causes pain: It is uncommon to have pain as a symptom of leukemia. But if you have it then it is likely to be from the bones, most often from the pelvic/low back area. But you should know what type of leukemia you are dealing with(?) as there are 4 different types which can be either acute or chronic leukemia, with entirely different symptoms from one to the other(s). ...Read more
See below...: Exposure to certain chemicals like benzene or formaldehyde may increase the risk for cancer including leukemia. This is probably due to the mutagenic effect of these agents, meaning they can induce mutations in otherwise normal cells resulting in abnormal cells that can become cancerous; however, the process is usually multifactorial and other conditions need to be met to develop cancer. ...Read moreSee 1 more doctor answer
The cell cycle: ...is activated in the immature "blast" cells of acute leukemia. This is not so much a defect, as it is also a normal attribute of immature blood cells. A major problem is the lack of maturation of these cells into normal non-dividing blood cells. Various transcription factors are mutated and these may cause increased proliferation. CLL is characterized by decreased apoptosis (cell death). ...Read more
Unknown: Most leukemias in adults and children do not have a specific etiology. Some leukemias in children can be linked to genetic abnormalities like down's syndrome, neurofibromatosis, bloom syndrome, and others. Ethnicity may play a role in all, hispanic children tend to have higer risk. High birth weight has been associated with higher risk though really this is unclear. Other factors are inconsistent. ...Read more
Most are due to muta: Mutations are common in all cancers. In Leukemia the very first mutation(Single mutation, causing cancer was discovered in Chronic Myelocytic Leukemia(CML). In most other Leukemias, there are multiple mutations present once we have learned how to search for them by Genomic profiling. ...Read more
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