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Doctor insights on: Can I Take Singulair With Benadryl

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Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Can my son take Benadryl (diphenhydramine) right now while taking Singulair? He takes Zyrtec also but we're out & he's suffering big time!! He's 13, 120 pounds.

Can my son take Benadryl (diphenhydramine) right now while taking Singulair? He takes Zyrtec also but we're out & he's suffering big time!! He's 13, 120 pounds.

Yes: It is safe for him to take Benadryl (diphenhydramine) with Singulair. Based on his weight he can take 50mg every 6-8 hours. It potentially can make him drowsy. All the best and I hope he feels better. ...Read more

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I'm having an allergy attack. I'm already prescribed Zyrtec and Singulair and still can't stop sneezing. Can I take Benadryl with these 2 meds and go to bed?

I'm having an allergy attack. I'm already prescribed Zyrtec and Singulair and still can't stop sneezing. Can I take Benadryl with these 2 meds and go to bed?

Allergy meds: Yes - there should be no reaction with the singulair and maybe a slight reaction (increased somnolence)the the zyrtec but since you are heading to bed that isn't an issue. You might want to double the dose of Zyrtec going forward as the 20 mg dose was actually better when the drug was being developed. ...Read more

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My 4 year old takes zyrtec 1 tsp and singulair 4mg every night. She got a couple mosquito bites yesterday and they are swollen. Can she have a dose of benadryl also tonight? Her left eye has also been watering for several days even with both allergy meds.

My 4 year old takes zyrtec 1 tsp and singulair 4mg every night. She got a couple mosquito bites yesterday and they are swollen. Can she have a dose of benadryl also tonight? Her left eye has also been watering for several days even with both allergy meds.

Allergy: A one time dose should be OK. Diphenhydramine is short acting while Zyrtec is long acting. So, there will be some overlap, but short lived. Adding Zantac (ranitidine) also helps improve the symptoms faster since the two groups of medications have a synergistic effect. ...Read more

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I take zyrtec and singulair (montelukast) daily in the morning. Is it ok to take benedryl also, in the evening, while visiting friends with pets for the weekend?

Yes you can: You can take extra Benadryl (diphenhydramine) but it would make you drowsy so you should not drive. If those do not help, you might need to seek help from a local allergist. ...Read more

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I have asthma & severe allergies, currently taking zyrtec, singulair (montelukast) and albuterol as needed. We are trying to conceive & I know antihistamines dry up mucus, what can I do to help my mucus in uterus?

I have asthma & severe allergies, currently taking zyrtec, singulair (montelukast) and albuterol as needed. We are trying to conceive & I know antihistamines dry up mucus, what can I do to help my mucus in uterus?

Complicated: Antihistamines can all interfere with ovulation by blocking the action of histamine, a chemical that also plays a role in releasing an egg from the ovary and implanting it in the womb. These drugs are effective at relieving the symptoms of an allergic reaction, but they may also halt conception. If you’re trying to get pregnant, it’s best to avoid antihistamines from mid-cycle until your period. ...Read more

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My daughter is taking montelukast and Qvar daily at night. She is 6 and has asthma. Can she take Benedryl at night for runny nose and terrible cold?

My daughter is taking montelukast and Qvar daily at night. She is 6 and has asthma. Can she take Benedryl at night for runny nose and terrible cold?

Met: Upper respiratory infections may cause worsening of asthma and an increased need for Albuterol.
Cold remedies are often not very useful, but nasal saline rinses and a vaporizer may help to relieve nasal symptoms. If she is allergic and being treated with an anti histamine, this can be continued. ...Read more

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How to recover from antihistaminic dysphonia? Ice-cream? Now 2nd day. I stop antihistamines and moved to Montelukast.

How to recover from antihistaminic dysphonia? Ice-cream? Now 2nd day. I stop antihistamines and moved to Montelukast.

Time: Give it a few days to recover. I presume that you were taking the older generation antihistamine (Benadryl, hydroxyzine etc) which tends to dry up the throat. If the problem is indeed from antihistamine, it will recover within days. In the meanwhile, lozenges, honey, lemon drop (sugar-free), ice cream or whatever soothes it can be taken. ...Read more

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Why bilateral armpit rash after swimming 1 min? I cannot use antihistamines 'cos severe anticholinergic effects (dysphonia, dry mucose). Montelukast.

Topical creme: There are multiple topical compounded cremes and ointments containing antihistamines which can be applied locally but not get absorbed systemically. Ask your doctor to prescribe some. ...Read more

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Nasal steroid sprays for rhinitis/thick PND, give me perioral dermatitis. Tried antihistamines, montelukast, ipratropium, PPIs as alternative. Ideas?

Nasal steroid sprays for rhinitis/thick PND, give me perioral dermatitis. Tried antihistamines, montelukast, ipratropium, PPIs as alternative. Ideas?

Saline: Irrigate 2-3 times daily with saline (via neti-pot or squeeze bottle). This is step one. Otherwise, physical exam and history are needed to determine rhinitis subtype (allergic, vasomotor, infectious, etc.). Good luck! ...Read more

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What happens if you take too much benadryl (diphenhydramine)?

What happens if you take too much benadryl (diphenhydramine)?

Benadryl (diphenhydramine): It ususally makes you have a dry mouth and get very sleepy. ...Read more

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Is it okay if to take 2 benadryls (diphenhydramine) and I melatonin?

Doses?: Depends on the dose of Benadryl (diphenhydramine). If you have insomnia, sleep hygiene is an often overlooked, yet more effective treatment, than medications. In addition, the combination of medications could impair decision making, cause undesired drowsiness, and other side effects. Speak with your doctor, before taking any combination of medications. Do not drive/operate heavy machinery under their influence. ...Read more

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Would it be ok to take Benadryl (diphenhydramine) that expired in 11/09?

Would it be ok to take Benadryl (diphenhydramine) that expired in 11/09?

Benadryl (diphenhydramine): Taking medication that expired almost 5 years ago is probably not a good idea. It may be safe, but I don't know for sure. If we were in the Zombie apocalypse and you had no other choice I would say go for it. But since generic diphenhydramine is cheap, why don't you make a trip to your local store and buy some new. ...Read more

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What would happen if someone takes a Benadryl (diphenhydramine) & 5mg vicdion together?

More sleepy: Nothing serious at these low doses although you may feel more sleepy since the sedation effects of ech medicine add up. But it should be fine after 12-18 hours. ...Read more

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Can you take meloxicam and Benadryl together?

Can you take meloxicam and Benadryl together?

Should be ok if...: If a person had no problems taking meloxicam (Mobic) in the past for some medical condition, and separately had no problem taking diphenhydramine (Benadryl) in the past, then she should be ok taking the medications at the same time. If worried, she can ask her doctor who prescribed the meloxicam. Benadryl does cause drowsiness, so can be unsafe for certain activities such as driving or piloting. ...Read more

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Can I take Benadryl (diphenhydramine) for hives?

Can I take Benadryl (diphenhydramine) for hives?

Yes: Benadryl (diphenhydramine) can make you drowsy so be cautious if you drive or do other activity. You need to see your physician to clarify why you have the hives. ...Read more

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Is it okay to take Benadryl on top of trazadone?

Increased sleepiness: Trazodone and benadryl are both medications that can be sedating. In general it would be safe to use them together with the caution that the sedating effects would be greater. It may be best to check with your physician to see if this is the right choice for you. ...Read more

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Would it be fine to take adderall with a benadryl?

Would it be fine to take adderall with a benadryl?

Talk 2 dr/pharmacist: There are no particular drug-drug interactions, but we don't know what other medications you are on, or what your other health issues are. Benadryl is mildly sedating and may antagonize some of the effects of adderall. An occasional benadryl for an allergic problem or insomnia is likely to be fine, while regular use of it may be a problem for you. Talk to your prescriber and/or your pharmacist. ...Read more

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Can I take Benadryl (diphenhydramine) with allegra?

Can I take Benadryl (diphenhydramine) with allegra?

Yes: You can take them together. If you are sensitive to the sedating effects of antihistamines, you should not take them at the same time. It would be better to take Allegra in the morning or afternoon and then Benadryl (diphenhydramine) in the evening before bed. However, if you don't feel sleepy after taking antihistamines, it would not be harmful to take them together. ...Read more

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Can I take Claritin with benadryl (diphenhydramine)?

Can I take Claritin with benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Latonya Brown-Puryear
258 Doctors shared insights

Montelukast (Definition)

Http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a600014.html. ...Read more