can i take pseudoephedrine and phenylephrine together

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Dr. John T. Chiu answered:

Can I take phenylephrine and pseudoephedrine together?

No

Blood
Both are decongestants and tend to raise your heart rate and blood pressure. In general, pseudoephedrine is more potent than phenylephrine .
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Dr. Alvin B. Lin answered:

Can I take Pseudoephedrine HCI with Lexapro? And what about Phenylephrine? The first one has been my preferred cold med for years.

DrugDrugInteractions

Talking_with_your_doctor
Yes, you can take Pseudoephedrine w/Lexapro (http://www.drugs.com/interactions-check.php?drug_list=1964-0,1013-565). However, it's always best to tell your prescribing doctor & dispensing pharmacist everything you're taking, whether prescription or OTC, so that they can pre-emptively look for drug-drug interactions before prescribing you something.
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Can you take phenylephrine and pseudoephedrine?

Not recommended

Blood
They are both decongestants and have similar effects. I recommend taking the highest effective dose for you of one or the other, not both. I tend not to recommend this to people with poorly controlled high blood pressure, prostate problems,or cardiovascular disease.
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Can you take Phenylephrine Hydrochloride or Pseudoephedrine Hydrochloride whilst taking amoxicillin ? I'm being treated for a middle ear infection.

Yes

Amoxil
These decongestants work well for some and generally will not interfere with your other treatment.
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Dr. Sean McGhee answered:

After took Panadol Cold and Flu (paracetamol, phenylephrine hydrochloride), can I take Actifed afterwards (triprolidine hydrochloride, pseudoephedrine?

No

Acetaminophen
You shouldn't use both at the same time. If you want to switch from one to the other, wait until it is time for your next dose of the panadol, but then take the actifed instead. They are different medicines, but act in almost exactly the same fashion, so taking them together will result in too high a dose.
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Dr. Robert Knox answered:

Is it safe to take phenylephrine with pseudoephedrine?

Phenylephrine

Pseudoephedrine
It is safe to combine phenylephrine with pseudoephedrine generally if you do not have high blood pressure. But, combining the two may increase your pulse, may create palpitations (sensation of heart flipping), or raise your blood pressure. Insomnia may also be associated with using the two together. They are both stimulants that shrink blood vessels.
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Dr. Bernstein Joel answered:

Is it possible for me to take phenylephrine with pseudoephedrine?

Not a good idea

Pseudoephedrine
Both of these OTC drugs usually used for nasal congestion are almost identical. They are alpha-agonists and as such increase heart rate and blood pressure as side effects. Take one or the other, not both.
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OTC phenylephrine doesn't work for me, but pseudoephedrine does. However, it can make me jittery. What should I try? Children's dose, perhaps?

Yes

Sudafed
If pseudoephedrine works but causes jitteriness try cutting the dose in half.
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What flue drugs dose not have pseudoephedrine or Phenylephrine ?

Tamiflu

Sudafed
But seriously, just read the label. Dont forget Zn tablets
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Dr. Bernstein Joel answered:

Would oral phenylephrine/pseudoephedrine help with rebound congestion?

Steroids

Viral_uri
I would recommend either Medrol dose-pak or prednisone 20 mg. three times a day for 5 days. Prednisone is the ultimate anti-inflammatory drug and the above 2 methods of administration are safe and should relieve rebound congestion. Obviously, stop taking over the counter nasal sprays. If you have nasal congestion, see an ENT doc or an allergist.
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