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Doctor insights on: Can I Take Methadone With Zoloft

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I am currently on 55 mg of Methadone daily. Is it safe for me to also take 12.5 mg of Zoloft daily?? Is this a dangerous combination??

I am currently on 55 mg of Methadone daily. Is it safe for me to also take 12.5 mg of Zoloft daily?? Is this a dangerous combination??

Potentially: Methadone and sertraline both have some potential to increase risk for an abnormal heartbeat. This risk is proportional to the dose (lower doses = lower risk). You describe low doses, but an ECG would be recommended when available to ensure safety.

Of course, it's always important to inform prescribing doctors of all other medication one is taking so that interactions can be considered. ...Read more

Dr. Stuart Wasser
655 doctors shared insights

Methadone (Definition)

Methadone is a synthetic opiate used for pain control and in the rehabilitation of opiate addicts. Methadone used in rehabilitation relieves craving, suppresses withdrawal symptoms, and blocks the euphoric effects associated with ...Read more


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I have been taking Zoloft (sertraline) 50mg for 2 weeks on top of methadone 80mg (1 year). I get really sleepy in the afternoon. Is it safe? I've read bad things.

Your doctor and the: Methadone program need to know about each other, and if not, make sure they do right away. Zoloft (sertraline), (sertraline) like all SSRIs, has the potential to be sedating, plus it can (although usually in higher doses) reduce metabolism of Methadone so that the blood levels go higher. Talk to the nurse at your program (or your pain doctor) to see if your Methadone dose needs a bit of lowering. Zoloft (sertraline) is a very safe drug ...Read more

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I'm having a problem starting urination for drug tests and sometimes at home, I take zanex, methadone, zooloft and vicadin 4 pain & depression asap luv?

I'm having a problem starting urination for drug tests and sometimes at home, I take zanex, methadone, zooloft and vicadin 4 pain & depression asap luv?

A lot of meds: All the meds you mention could potentially cause urinary hesitancy and retention especially when taken all togeter. Discuss this with your prescribing doc. ...Read more

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I can't remember if I took my Zoloft (sertraline) (100mg) should I take one just in case?

I can't remember if I took my Zoloft (sertraline) (100mg) should I take one just in case?

No use should not: Since you can't remember if you took one already, if you take another, you will have taken too much. The risk of side effects from taking too much is greater than missing 1 dose. ...Read more

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Can I take my zoloft (sertraline) the next day if I didn't sleep or would it be like taking it twice?

Can I take my zoloft (sertraline) the next day if I didn't sleep or would it be like taking it twice?

Insomnia: Zoloft (sertraline) Dose is once in 24 hours.
It is likely that your Sleep problem is due to side effect of Zoloft (sertraline) or Stress.
Let Wise Person within you reflect Stresses with causing insomnia.
Consider:
Avoid • Alcohol • OTC Sleep aids
Exercise or Yoga in the evening
Before sleeping:
• Close that day’s Chapter in Book of Life
• Visual imagery of National Parks
• Breathing Relaxation
• Therapy • Medication ...Read more

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How long do u take Zoloft (sertraline) for. I've been on it 1 month. I don't want to go all summer without a drink. I'm on 0.50 mgs and feel better?

How long do u take Zoloft (sertraline) for. I've been on it 1 month. I don't want to go all summer without a drink. I'm on 0.50 mgs and feel better?

6 months or longer: I'm glad you're feeling better. Zoloft (sertraline) is used to treat depressive and anxiety disorders, so the length of time you will need on it will depend on your diagnosis. Some conditions, like a single major depressive episode, require at least six months to ensure adequate treatment. For some conditions, zoloft (sertraline) is prescribed indefinitely. Careful about alcohol. It will reduce the effectiveness of zoloft (sertraline). ...Read more

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Do I have to take 2 urine tests one is a methadone and the other a drug panel if the dr didn't discuss them to me?

Drug Testing: Pain: Pain management allows a physician to demand regular screening for drugs, especially those they are prescribing. If you do not do the drug screening the physician has a right to stop prescribing the medications you are on. ...Read more

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I've been taking 1 50mg Zoloft (sertraline) a day, it hasn't been helping. Would it hurt me if I take 2 of the 50mg a day?

I've been taking 1 50mg Zoloft (sertraline) a day, it hasn't been helping. Would it hurt me if I take 2 of the 50mg a day?

Don't know: What condition you are being treated for? Don't know how long you have been on this dose? It can take 4 to 6 weeks to get a full response of zoloft (sertraline) at your current dose. Please don't make any changes to your medications without discussing with your physician/ psychiatrist. ...Read more

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Why can't I take oxyelite pro while I'm taking zoloft (sertraline)? I'm in medical field so complicated answer is okay

Why can't I take oxyelite pro while I'm taking zoloft (sertraline)? I'm in medical field so complicated answer is okay

Unregulated: All supplements are unregulated by fda, so they can put 'pro' and 'awesome' and whatever you want to hear to get excited and spend money, but the fact is there are things they can put that do work, and are dangerous. I see kidney stones, heart, liver and other problems that come from muscle and energy supplements. So with or without zoloft, (sertraline) I wouldn't recommend that stuff. ...Read more

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I haven't taken my medication (Zoloft 200mg and Lamictal 200mg) for 2 weeks. Should I take my full dose again or half?

I haven't taken my medication (Zoloft 200mg and Lamictal 200mg) for 2 weeks. Should I take my full dose again or half?

Do you need them?: These are antidepressants. If you function well without using them, then stay off of taking them completely. Otherwise, you can go back on them(if you remain depressed without using them.)
These doses if tolerated before are fine to take them like before. ...Read more

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I asked a question before about which could medications I could take with zoloft (sertraline). I didn't get an answer, and I can't sleep due to this cough.

I asked a question before about which could medications I could take with zoloft (sertraline). I didn't get an answer, and I can't sleep due to this cough.

Some remedies: A mixture of chamomile tea with honey & a small amount of lemon juice may help. Pour boiling water over thinly sliced organic ginger. Steep for at least five minutes in a covered pot. Add 2 to 3 tbs of honey & sip. Hydrate well with broth or water. These are just a few options. Take care. ...Read more

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Dr prescription me 5mg methadone 3x a day for pain. I also take ambiencr 12.5. Dr didn't mention anything but I read it could make me stop breathing. This true?

Dr prescription me 5mg methadone 3x a day for pain. I also take ambiencr 12.5. Dr didn't mention anything but I read it could make me stop breathing. This true?

Yes: Methadone and Ambien (zolpidem) are 2 medications that when taken in high doses may affect your respiratory rate. An overdose of either of these medications can cause you to stop breathing. Generally, if you are tolerating Methadone without any adverse affects, then combining it with Ambien (zolpidem) should not be a problem. You may also try a dose of Ambien (zolpidem) that is smaller, usually 6.25 mg is sufficient. ...Read more

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I didn't take my night dose of Zoloft (sertraline) & strattera! What can happen? I already didn't see benefit on meds. Will this missed dose affect its effectivity?

Not a Problem: Skipping a day in taking these medications will not be a problem. Just take your next scheduled dose. The effectiveness for both drugs will depend on amount of drug and the time it is in the system. Both depend on time to know if they will be effective. Give 4 weeks for both, then ask your doctor if should increase the doses. ...Read more

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Can you explain how this combination works? I take 25mg Zoloft (sertraline) 1 MG Ativan at night. I had 3 drinks and blacked out with no memory for about 7 hours. I won't be doing this again but I am very curious as to the combination. I am planning on c

Not advisable: Ativan will commonly cause amnesia. You should not drink in combination with the Ativan, the result can be as you found, but can be more serious including death. Your dose of Zoloft (sertraline) is very low, and not likely an interaction with either the alcohol or ativan. ...Read more

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I'm coming off of methadone can I take soboxone to feel better? I've been away from where I live and haven't taken my methadone for 2 days

Methadone & Suboxone: You need to stop Methadone for several days and be in full withdraw for Suboxone induction. Mixing Methadone and Suboxone would cause withdrawal.
The dosage for Suboxone will be determined by your doctor during the induction. Please see a doctor asap. ...Read more

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If I took methadone a couple of days ago, would it be more dangerous than it usually would to take mdma, beacouse of the methadone that still haven't left the body, or what's the deal here?

They don't interact: Both drugs are clearly harmful for different reasons. Methadone is an opiate which can suppress respiration, or lead to overdose. Mdma can have damaging effects on the brain with even a single use. ...Read more

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What is it like to take zoloft (sertraline)?

Dr Martínez-Irizarry: Is right. It is well tolerated in general but possible side effects start right away. Getting the full benefit of the medication — usually takes 4 to 6 weeks once on optimum dose. It is important to know this so that you are patient. It can be helpful for tx of treatment of major depressive disorder, panic disorder, social anxiety disorder, post-traumatic disorder, obsessive compulsive disorder ...Read more

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My grandma has copd, could she take methadone?

My grandma has copd, could she take methadone?

Copd: Avoidance of any type of narcotic therapy is typically advised in patients with copd. Narcotics have the potential of making a patient not be able to expire carbon dioxide which could be life threatening. If a patient has been on narcotics for a long time, the chance of this is less, if they are not increasing the dose. ...Read more

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Can I take pexeva with zoloft (sertraline)?

Can I take pexeva with zoloft (sertraline)?

Depends....: Sometimes two antidepressants may be used at the same time in some cases but the choice of which ones depends on the condition and symptoms being targeted and potential side effects and interactions. Discuss with your treating md to see if another combination of mess will be best for you. ...Read more

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Can you take Zoloft (sertraline) and loratab?

Can you take Zoloft (sertraline) and loratab?

Depends....: Zoloft (sertraline) is an antidepressant, lortab is an opioid pain med. If you suffer from depression and you are in pain your dr may prescribe lortab. Zoloft (sertraline) however can cause side effects -- make you more depressed or even suicidal. Lortab can cause side effects and if taken long enough, addiction.
These meds should only be taken if prescribed for you by your physician. ...Read more

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Can u take Zoloft (sertraline) with benedryl?

Can u take Zoloft (sertraline) with benedryl?

Yes: Benadryl (diphenhydramine) has some potential to cause drowsiness in some people while zoloft usually does not. If needed, I feel you're taking Benadryl (diphenhydramine) while on zoloft should cause no problems. Your psychiatrist who is an expert in working with medications like zoloft would be best to answer this question, however. ...Read more

Dr. Heidi Fowler
1,094 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


Dr. Heidi Fowler
1,048 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more