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Doctor insights on: Can I Take Methadone With Zoloft

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Dr. Stuart Wasser
638 doctors shared insights

Methadone (Definition)

Methadone is a synthetic opiate used for pain control and in the rehabilitation of opiate addicts. Methadone used in rehabilitation relieves craving, suppresses withdrawal symptoms, and blocks the euphoric effects associated with ...Read more


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I have been taking Zoloft (sertraline) 50mg for 2 weeks on top of methadone 80mg (1 year). I get really sleepy in the afternoon. Is it safe? I've read bad things.

Your doctor and the: Methadone program need to know about each other, and if not, make sure they do right away. Zoloft (sertraline), (sertraline) like all SSRIs, has the potential to be sedating, plus it can (although usually in higher doses) reduce metabolism of Methadone so that the blood levels go higher. Talk to the nurse at your program (or your pain doctor) to see if your Methadone dose needs a bit of lowering. Zoloft (sertraline) is a very safe drug ...Read more

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I can't remember if I took my Zoloft (sertraline) (100mg) should I take one just in case?

I can't remember if I took my Zoloft (sertraline) (100mg) should I take one just in case?

No use should not: since you can't remember if you took one already, if you take another, you will have taken too much. The risk of side effects from taking too much is greater then missing 1 dose. ...Read more

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Can I take my zoloft (sertraline) the next day if I didn't sleep or would it be like taking it twice?

Can I take my zoloft (sertraline) the next day if I didn't sleep or would it be like taking it twice?

Insomnia: Zoloft (sertraline) Dose is once in 24 hours. It is likely that your Sleep problem is due to side effect of Zoloft (sertraline) or Stress. Let Wise Person within you reflect Stresses with causing insomnia. Consider: Avoid • Alcohol • OTC Sleep aids Exercise or Yoga in the evening Before sleeping: • Close that day’s Chapter in Book of Life • Visual imagery of National Parks • Breathing Relaxation • Therapy • Medication ...Read more

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How long do u take Zoloft (sertraline) for. I've been on it 1 month. I don't want to go all summer without a drink. Im on 0.50 mgs and feel better?

How long do u take Zoloft (sertraline) for. I've been on it 1 month. I don't want to go all summer without a drink. Im on 0.50 mgs and feel better?

6 months or longer: I'm glad you're feeling better. Zoloft (sertraline) is used to treat depressive and anxiety disorders, so the length of time you will need on it will depend on your diagnosis. Some conditions, like a single major depressive episode, require at least six months to ensure adequate treatment. For some conditions, zoloft (sertraline) is prescribed indefinitely. Careful about alcohol. It will reduce the effectiveness of zoloft (sertraline). ...Read more

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Can you explain how this combination works? I take 25mg Zoloft (sertraline) 1 MG Ativan at night. I had 3 drinks and blacked out with no memory for about 7 hours. I won't be doing this again but I am very curious as to the combination. I am planning on c

Can you explain how this combination works? I take 25mg Zoloft (sertraline) 1 MG Ativan  at night. I had 3 drinks and blacked out with no memory for about 7 hours. I won't be doing this again but I am very curious as to the combination. I am planning on c

Not advisable: Ativan will commonly cause amnesia. You should not drink in combination with the Ativan, the result can be as you found, but can be more serious including death. Your dose of Zoloft (sertraline) is very low, and not likely an interaction with either the alcohol or ativan. ...Read more

Dr. Donald Jacobson
1,041 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


Dr. Alan Ali
993 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more