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Doctor insights on: Can I Take Benadryl And Zyrtec Together

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Is it safe to take Benadryl (diphenhydramine) and Zyrtec together? I was put on Zyrtec for an allergic reaction with steroids for swelling and it's keeping me awake.

Is it safe to take Benadryl (diphenhydramine) and Zyrtec together? I was put on Zyrtec for an allergic reaction with steroids for swelling and it's keeping me awake.

Zyrtec (cetirizine) not the cause: It's unlikely that Zyrtec is keeping you awake. If anything, it usually causes drowsiness. You can take one dose of Benadryl (diphenhydramine) with Zyrtec, although it's not usually recommended as it may cause dizziness or excess sedation. ...Read more

Dr. John Chiu
1,047 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Is it okay to take zyrtec with benadryl (diphenhydramine)?

Is it okay to take zyrtec with benadryl (diphenhydramine)?

Not really: These are both antihistamines. If both are needed then physician guidance should be sought. ...Read more

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Is it ok to take zyrtec after you've taken benadryl (diphenhydramine)?

Is it ok to take zyrtec after you've taken benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). ...Read more

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Can you take zyrtec during day and Benadryl (diphenhydramine) at night?

Zyrtec and Benadryl (diphenhydramine): Hello. These two antihistamines taken together will probably cause sedation. As physicians, we often times double up on antihistamines in challenging cases but I usually use non-sedating antihistamines when I do this. There are other medications that may work better than this combination. Check with your doctor for other options. ...Read more

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Is safe if I take Benadryl (diphenhydramine) six hours after take zyrtec?

Is safe if I take Benadryl (diphenhydramine) six hours after take zyrtec?

Should be ok: While taking Benadryl (diphenhydramine) after zyrtec should be ok, it would be even better to know the underlying trigger to allow less medication usage. An allergist could determine why symptoms are not controlled with less medication. ...Read more

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Should I take Benadryl (diphenhydramine) until my zyrtec really kicks in?

Should I take Benadryl (diphenhydramine) until my zyrtec really kicks in?

Probably not helpful: Both drugs need to be absorbed by the GI system before they take effect to stop itching and sneezing (can take up to 1 hr). Benadryl (diphenhydramine) can dry up mucus (and make you sleepy), which zyrtec will not do at any time. If you have taken zyrtec for several days without relief from itching or sneezing, you may have something besides allergies (e.g. A cold) or need a different treatment. See your doctor. ...Read more

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I had zyrtec about 6 hours ago. Can I take Benadryl (diphenhydramine) now?

I had zyrtec about 6 hours ago. Can I take Benadryl (diphenhydramine) now?

Yes you can: Yes you can if your symptoms are not controlled with zyrtec (cetirizine) alone for short period. ...Read more

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Is it possible for you to take zyrtec and Benadryl (diphenhydramine) in the same day?

Is it possible for you to take zyrtec and Benadryl (diphenhydramine) in the same day?

Yes you can: You can take both medications at the same time providing that you follow the recommended otc doses. ...Read more

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Can you tell me is it ok to take zyrtec for daytime and Benadryl (diphenhydramine) for night?

Can you tell me is it ok to take zyrtec for daytime and Benadryl (diphenhydramine) for night?

Yes it is ok: Yes it is ok as long as you are using it for short period when your allergy symptoms are not controlled with zyrtec (cetirizine) and you are not able to sleep due to allergy symptoms. ...Read more

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Well, I took Benadryl (diphenhydramine) about 12 hours ago and I was wondering, may I take zyrtec?

Antihistamines: Yes you can, but you really should have some doctor guidance with your medications, because you did not mention what symptoms you are treating with the antihistamines and they may not be the ideal medication if you are not responding to one and need to add another. Talk to your doctor. ...Read more

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I took a zyrtec about 12 hrs ago and was wondering if it was ok to take one benadryl (diphenhydramine)?

Yes: It is not harmful to take Benadryl (diphenhydramine) after Zyrtec- both medications are antihistamines and generally you would not need to take both of them

Benadryl (diphenhydramine) is a stronger antihistamine and may help with symptoms unresolved by Zyrtec - it often has more sedation as side effect than Zyrtec ...Read more

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Is it safe to take both zyrtec and benadryl (diphenhydramine)?

Is it safe to take both zyrtec and benadryl (diphenhydramine)?

Not a good choice: Benadryl (diphenhydramine) is a short acting antihistamine. Zyrtec is a long acting antihistamine. You may overdose if taking both at the same time or taking both in the same day. Consider a better allergy medication if zyrtec is not working well or if you have been taking Benadryl (diphenhydramine) longer than 5 days. ...Read more

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Can I take zyrtec d and benadryl (diphenhydramine) at the same time?

Can I take zyrtec d and benadryl (diphenhydramine) at the same time?

Better not: Unless you have severe allergic reaction, and only once, otherwise it is not advisable, if you have uncontrollable allergies, better see an allergist, check aaaai. Org or caai. Org for an allergist in your area ...Read more

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Is it safe to take zyrtec and Benadryl (diphenhydramine) at the same time?

Is it safe to take zyrtec and Benadryl (diphenhydramine) at the same time?

No: Both zyrtec and Benadryl (diphenhydramine) belong to the same class of medicines called antihistamines. Taking both at the same time would be taking a double dose of medicine.
Zyrtec is taken once every 12 hours, whereas Benadryl (diphenhydramine) is taken every 4 to 6 hours. ...Read more

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I took Zyrtec this morning but am so congested would it be okay to take Benadryl (diphenhydramine) too?

Decongestant: zyrtec and benadryl (diphenhydramine) are antihistamines. If you are congested, you might consider taking a decongestant ...Read more

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I take 1 zyrtec in the morning and 2 benadryl (diphenhydramine) at bedtime. Is that to much antihistmine?

Yes: First depends on the dose and age but yes, zyrtec is a 24 hour medication and Benadryl (diphenhydramine) is a 6-8 hour med. Routinely this should not be ongoing. If symptoms are persistent look into another cause. ...Read more

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Can I give my 2 year old children's Benadryl (diphenhydramine) at night.... and how much.....she takes zyrtec in the morning?

Can I give my 2 year old children's Benadryl (diphenhydramine) at night.... and how much.....she takes zyrtec in the morning?

Zyrtec (cetirizine) + Benedryl: The occassional use of Benedryl for breakthrough allergy symptoms in addition to regular use of Zyrtec (cetirizine) should generally not cause any problems. Dosing of Benedryl is based on your child's current weight. A simple phone call to your pediatrician should be all that is needed to confirm that the appropriate doses of Zyrtec (cetirizine) and Benedryl are being given. ...Read more

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I just took zyrtec for hives, can I take Benadryl (diphenhydramine) at night?

Zyrtec ; Benadryl (diphenhydramine): Hello, you can take zyrtec and Benadryl (diphenhydramine) together on the same day. You may notice a little sedation. If so., do not put yourself or anyone else in harm's way. ...Read more

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Is it possible to take zyrtec in the morning and Benadryl (diphenhydramine) at night for my allergies?

Is it possible to take zyrtec in the morning and Benadryl (diphenhydramine) at night for my allergies?

Yes: As long as you tolerate the medicines and do not experience drowsiness that is ok. Otherwise ask you doctor for a prescription nasal spray to take with zyrtec. ...Read more

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I take Zyrtec nightly for my allergies. I took a Benadryl tonight cause I was having worse symptoms today. Am I okay to take a Zyrtec tonight?

No: I would not recommend taking Zyrtec and Benadryl together as they are both antihistamines with similar mechanisms of action and side effects can be increased. ...Read more

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Can my son take Benadryl (diphenhydramine) right now while taking Singulair? He takes Zyrtec also but we're out & he's suffering big time!! He's 13, 120 pounds.

Can my son take Benadryl (diphenhydramine) right now while taking Singulair? He takes Zyrtec also but we're out & he's suffering big time!! He's 13, 120 pounds.

Yes: It is safe for him to take Benadryl (diphenhydramine) with Singulair. Based on his weight he can take 50mg every 6-8 hours. It potentially can make him drowsy. All the best and I hope he feels better. ...Read more

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Should I take Benadryl (diphenhydramine) or zyrtec for a cat allergy?

Should I take Benadryl (diphenhydramine) or zyrtec for a cat allergy?

Depends: If you only have eye itching, runny nose, or sneezing, either may help but can make you groggy (especially with Benadryl). However if you have asthma or nasal congestion, you are out of luck. If the cat allergy is severe, nothing will work well with continuing exposure and allergy shots may be your best bet. ...Read more

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Is it possible for me to take ultram, Benadryl (diphenhydramine) and zyrtec d?

Yes it is possible: However the combination might make you sedated and feel impaired significantly if you are not used to taking them together. ...Read more

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What is better to take the itching out of a mosquito bite, zyrtec or benadryl (diphenhydramine)?

What is better to take the itching out of a mosquito bite, zyrtec or benadryl (diphenhydramine)?

Benadryl (diphenhydramine): Both will work, but I find that Benadryl (diphenhydramine) does a better job of taking the edge off the itching. Only problem is the drowsiness it can cause (maybe that's why it works well!). ...Read more

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I'm allergic to benadryl, (diphenhydramine) have been since I was little. I stopped breathing and swelled up. What else can I take? Is zyrtec okay?

I'm allergic to benadryl, (diphenhydramine) have been since I was little. I stopped breathing and swelled up. What else can I take? Is zyrtec okay?

Allergy to benadryl (diphenhydramine): If you had such a severe reaction years ago to benadryl, (diphenhydramine) you should be under the care of an allergist to help protect you, from other allergy attacks that could be severe. It may be that you reacted to something that was in the Benadryl (diphenhydramine) rather than Benadryl (diphenhydramine) itself. ...Read more

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Terrible hives&hot flashes. Rx'd 10mg zyrtec daily&often take benadryl (diphenhydramine) at bedtime. Safe 2gether? What about 20mg zyrtec w benadryl (diphenhydramine)? What else wrks 4 hives

Avoid combination: Both Zyrtec & Benadryl (diphenhydramine) are antihistamines and as such, should not be taken together in same 24hr period due to potential interactions (http://www. Drugs. Com/interactions-check. Php? Drug_list=896-1617, 569-286). Maximum dose of Zyrtec is 10mg daily so best to avoid exceeding that amount. Check out goo. Gl/2dmzkm, goo. Gl/v31okZ & http://goo. Gl/uYTfTC for more info re chronic urticaria (hives). ...Read more

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I have bad seasonal allergies, zyrtec and clartin aren't working. Can I take Benadryl (diphenhydramine) with the zyrtec?

I have bad seasonal allergies, zyrtec and clartin aren't working. Can I take Benadryl (diphenhydramine) with the zyrtec?

OTC allergy meds: Combining Benadryl (diphenhydramine) and zyrtec may make you very drowsy so take it at night. You may like to try fexofenadine or Allegra instead; it's also non-sedating and can be taken once a day. Zyrtec and Claritin have derivatives that can be obtained only by prescription from your doctor. There are also nasal sprays that your doctor may try on you. ...Read more

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My friend has a food allergy reaction. We are unable to access Benadryl (diphenhydramine) (in Saudi Arabia). What action can we take? How much Zyrtec can she take?

My friend has a food allergy reaction. We are unable to access Benadryl (diphenhydramine) (in Saudi Arabia). What action can we take? How much Zyrtec can she take?

The recommended dose: Take 10mg daily as is the recommended dose. There are several other anti-histamines other than benadryl (diphenhydramine) that could be prescribed to her if the allergy is severe. Certainly avoid the foods first and foremost. ...Read more

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I had an allergic reaction (bugbite) and was given steroids and zyrtec. Can I take Benadryl (diphenhydramine) for itch before bed if I take both of those in the morning?

I had an allergic reaction (bugbite) and was given steroids and zyrtec. Can I take Benadryl (diphenhydramine) for itch before bed if I take both of those in the morning?

Yes: Benadryl (diphenhydramine) is one of the best anti-itch antihistamines, and can be taken together with zyrtec and steroids. The only caution is that as you take more antihistamine, there is an increased likelihood of drowsiness. This obviously isn't a problem at bedtime, and will help you sleep through the itchiness, but be very careful about taking extra antihistamines if you'll be driving or operating machinery. ...Read more

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Can I take Zyrtec in the morning and Benadryl (diphenhydramine) at night for postnasal drip? Need relief in the morning. Going to ENT in December.

Can I take Zyrtec in the morning and Benadryl (diphenhydramine) at night for postnasal drip? Need relief in the morning. Going to ENT in December.

Yes: Postnasal drip:

Every day, glands in the linings of your nose make about a quart of mucus each day.

The excess can come out of the nostrils -- that’s a runny nose. When the mucus runs down the back of your nose to your throat, it's called postnasal drip.

http://www. Webmd. Com/allergies/postnasal-drip ...Read more

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I am pregnant and took my otc zyrtec this morning. Now my nose is stopped up, is it safe to go ahead and take a dose of benadryl (diphenhydramine) @ 8p?

Yes but: Neither Zyrtec nor Benadryl (diphenhydramine) are expected to help for a stopped up nose. Runny nose, yes. There are other options that are also relatively safe to take during pregnancy. Nasal saline is a non-medicine option that has helped many. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. John Chiu
572 Doctors shared insights

Cetirizine (Definition)

Ceftirizine is the generic name of an antihistamine previously marketed under the ...Read more