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Doctor insights on: Can I Take Benadryl And Claritin Together

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Can you take Benadryl (diphenhydramine) and Claritin together ?

Can you take Benadryl (diphenhydramine) and Claritin together ?

Antihistamines: They are both antihistamines, so i wouldn't take them together. They both act similarly, so their effect would be too much together. Wait until one wears off before trying the other, about 24 hours or so. ...Read more

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Dr. John Chiu
1,011 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Depends: They are both in the same family (antihistamines), but a few people have daytime symptoms so take non-sedating med (like loratadine) and its effect wears off before next day's dose, so take a sedating (/older) antihistamine (like benadryl) at bedtime for continued relief and to aid with sleep. If no heart / urinary / blood pressure issues and no other meds to conflict with, not likely a problem. ...Read more

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Can i take Claritin and Benadryl (diphenhydramine) together and drink it down with an alka-seltzer?

Can i take Claritin and Benadryl (diphenhydramine) together and drink it down with an alka-seltzer?

Maybe: Depending on what you are treating, i would space them out, take Claritin in the morning and Benadryl (diphenhydramine) at night. Benadryl (diphenhydramine) is sedating though, so be careful driving or operating machines. Not sure what you are treating though. I can see that with urticaria but for nasal allergies, i would use a nasal spray instead of a second antihistamine. Alka seltzer will only help pain because it has aspirin. ...Read more

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Can I take Zyrtec and Claritin together? Or can I take Zyrtec and Benadryl (diphenhydramine) to boost the Zyrtec? Will taking Mucinex DM along with Zyrtec help?

See your doctor: If your allergies are not controlled with one med alone, stepping up to a different med like flonase, nasonex, etc., will likely help you more than taking two antihistamines. Zyrtec and Claritin will not help much at all if you have a cold and not allergies, though Benadryl (diphenhydramine) can dry up secretions somewhat. You can add Mucinex if you also have a cough. Talk with your doctor about your symptoms. ...Read more

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Can I take diphenhydramine and loratadine together?

Can I take diphenhydramine and loratadine together?

Yes: Taking Loratadine in the morning and Diphenhydramine at night will help you avoid the drowsiness side effects of Diphenhydramine and help you if the Loratadine is not controlling your symptoms for the full 24 hours. ...Read more

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Can i take loratadine and diphenhydramine together?

Can i take loratadine and diphenhydramine together?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness ( the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Can i take Claritin with benadryl (diphenhydramine)?

Can i take Claritin with benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness ( the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Can i take Benadryl (diphenhydramine) after claritin?

Can i take Benadryl (diphenhydramine) after claritin?

2 antihistamines: Even though both Benadryl (diphenhydramine) and Claritin are both antihistamines, there should not be significant interaction or side effects if taken at the usual doses. ...Read more

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Cani take Benadryl (diphenhydramine) with loratadine?

Probably yes.: Many people report their 'daily' non-sedating antihistamine in the am does not provide relief until next am. So, if no concerns for gu/heart/bp/med-conflict issues, then they often take a 'sedating' antihistamine at night for continued symptom relief and 'bonus' of sleep aid effect. ...Read more

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Can you take Benadryl (diphenhydramine) with claritin?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. However, if Claritin (loratadine) is not solving the problem, alternatives such as Allegra or zyrtec should be considered. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Ashraf Abdel Azeem
506 doctors shared insights

Claritin (Definition)

Claritin is a non-sedating antihistamine which is a kind of antihistamine type drug (common ...Read more