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Doctor insights on: Can I Take Aleve If I Am On Prednasone

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Is it ok to take Aleve (naproxen) pain med. With prednisone?

Is it ok to take Aleve (naproxen) pain med. With prednisone?

Yes, but...: Prednisone can make the stomach less well protected against irritants like aleve, (naproxen) so watch for new stomach symptoms. ...Read more

Dr. Thomas Namey
2,560 Doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


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I've been prescribed prednisone for my sinus infection. I take 1 daily for 5 days. I took 1 yesterday at 1:00 p.m. I took 2 aleve at 7:30 A.M, can I take my prednisone or will it cause damage?

I've been prescribed prednisone for my sinus infection. I take 1 daily for 5 days. I took 1 yesterday at 1:00 p.m. I took 2 aleve at 7:30 A.M, can I take my prednisone or will it cause damage?

Yes but: Do realize that this combination increases your risk of having stomach inflammation and even bleeding. Are you also on an antibiotic since Prednisone is not the usual medication for sinusitis if taken alone? ...Read more

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What can I take with Prednisone? Advil? Tylenol (acetaminophen)? Aleve?

What can I take with Prednisone? Advil? Tylenol (acetaminophen)? Aleve?

Either.: You can take Tylenol (acetaminophen) AND Advil OR Aleve. Do not take both Aleve and Advil as they are the same class (NSAIDs). If you wish for more pain control, you can take tylenol (acetaminophen) as directed & also take one of the NSAID's in between Tylenol (acetaminophen) doses. Don't exceed the rec. Dose of either one. But you may take the recommended dose of each, just not within an hour of each other. Using them both increases relief. ...Read more

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I'm on prednisone for sinus infection. I have a leg cramp from work. Safe to take Aleve (naproxen) for pain on this medication?

I'm on prednisone for sinus infection. I have a leg cramp from work. Safe to take Aleve (naproxen) for pain on this medication?

Let your doctor know: And see what they say and have it recorded in your chart. Usually it's safe, But your doctor knows your history, other medications, medical conditions, things that would make a better decision if s/he knew about it first to then advise you on it now. ...Read more

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I'm taking Prednisone 10 Mg 2 tabs /Am 3 days. Can I take aleve (naproxen) with it. I'm taking norco 10/325 for Knee Pain. Do I need call my doctor. Thanks?

I'm taking Prednisone 10 Mg 2 tabs /Am 3 days. Can I take aleve (naproxen) with it. I'm taking norco 10/325 for Knee Pain. Do I need call my doctor. Thanks?

Prednisone (steroid): Norco (acetaminophen and oxycodone--a narcotic) and Aleve (naproxen) (NonSteroidal Anti-inflammatory Drug) all work it different ways to alleviate inflammation & pain. In theory, they could all be used together, but, since you're in THAT much pain, yes, you should run this by your doctor. Best wishes! Dr. Anne. ...Read more

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Lower back pain and my doc pres. Naproxen 500 mg 2 x along with prednisone. And pain not going. Can I take ibobrufen 400 3x instead neproxin

Okay: Hello and thanks for using HealthTap. Yes it is okay to use ibupofen as you have indicated instead of the naproxen, just don't use them together. Be aware that the combination prednisone and another anti-inflammatory drug is very hard on your stomach. Consider taking an OTC prilosec once a day for stomach protection while you are on this combination. ...Read more

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I took 2 aleve 2 hours ago and I am still in pain, I also took a 20 mg prednisone how long before I feel better?

Pain: You never said what's in pain, or what's the cause of the pain. Obviously if OTC analgesics combined with steroid are not giving you relief, you require a different course of treatment. If your pain is from dental cause, see your Dentist. If from medical cause, see your Physician. You are treating symptoms, not the cause of the pain. You need more help than just self-medication. ...Read more

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Prednisone and naproxen sodium...Compatibility?

Prednisone and naproxen sodium...Compatibility?

Probably OK: Both of these drugs can irritate the stomach, and together they can be a one-two punch. However, many patients do just fine especially if they did not have stomach issues to start with. Your prescribing md will be able to tell you what to watch out for. ...Read more

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Is Minulet efficacy affected by plasmoquine, prednisone, naproxen, esomeprazole or indomethyacin? Is the ethinylestradiol or gestodene inhibited?

Contact Pharmacist: Good Afternoon,

I am a urologist and not familiar with the drug interactions of Minulet. Please contact your pharmacist while taking extra precautions until you have been given clarity regarding this issue.

Kind regards,
Aslam Bhorat ...Read more

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Active 26 yo with debilitating muscle/bone pain 9 mnth my clothes feel like weights 20mg prednisone 1000mg naproxen no help ANA1:320 RF DNA neg?

Active 26 yo with debilitating muscle/bone pain 9 mnth my clothes feel like weights 20mg prednisone 1000mg naproxen no help ANA1:320 RF DNA neg?

Diagnosis?: It sounds like you've had part if a work up for autoimmune disease with a somewhat significant elevation of ANA titer, and you have joint pains. It's important to do joint and long bones films as well as more specific immune testing to get you better pain relief and specific autoimmune treatment. Find a reliable Rheumatologist and get started... ...Read more

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If prednisone 20mg daily does not work is appropriate next step to start 500mg naproxen 2x daily and MRI for severe joint pain/morning stiffness?

If prednisone 20mg daily does not work is appropriate next step to start 500mg naproxen 2x daily and MRI for severe joint pain/morning stiffness?

See below: Not Really! If you're having multiple joint arthralgias a thorough workup usually is preferred with a rheumatologist and there's new medication that should control your symptoms. Good luck thank you ...Read more

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What could cause widespread bone/joint and muscle aches not relieved by 20mg prednisone or 500mg naproxen? Not arthritis ANA 1:320 DNA neg

That is not a high: Dose of prednisone or naproxen. You'll need to discuss this with your doctor with your history of thyroid cancer, and thyroidectomy. It may affect your muscles, and bone and your Vitamin D3 levels and other lab values not mentioned may be more important to determine systemic causes. ...Read more

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Can I take Aleve if I take a diuretic 12.5 mg daily. I'm taking Tylenol (acetaminophen) but not helpn a lot. Also take 40 mg propranolol daily?

Can I take Aleve if I take a diuretic 12.5 mg daily. I'm taking Tylenol (acetaminophen) but not helpn a lot. Also take 40 mg propranolol daily?

Yes, if kidneys OK: If your kidney (renal) function is normal, it should not be a problem, if not, check with your nephrologist. Make sure to take any NSAID such as Aleve (naproxen) with food, or it can burn a hole in your stomach lining and get a bleeding ulcer. ...Read more

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Can I take mucinex d and aleve at the same time?

Can I take mucinex d and aleve at the same time?

Interactions?: Yes, this is a common combination for treatment of cold symptoms. You might prefer to take with food to minimize nausea, particularly the Aleve. You could also take an hour or so apart if taking all that medicine at once causes nausea.
Feel better soon. ...Read more

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Can you take Lunesta (eszopiclone) and Aleve together?

Can you take Lunesta (eszopiclone) and Aleve together?

Yes: There should be no problem taking these medications together. Remember that Aleve (naproxen) should be taken with food. Feel better and get some good sleep. ...Read more

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I took one aleve 4hrs ago. Can I take my 15mg Meloxicam now?

I took one aleve 4hrs ago. Can I take my 15mg Meloxicam now?

Better wait 4 more: Hours, the two are NSAIDs and side effects can be an issue if taken too soon. Acetaminophen (Tylenol) can be used in the interim to control pain/fever if you wish, have a good day ...Read more

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Is it ok to take 3 aleves (naproxen) at a time?

No: This is considered an overdose of the medication. If you are having that much pain and inflammation, consult your doctor for a proper dosage of medicine or a prescription. ...Read more

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What happens if you take too much aleve (naproxen)?

No!: Can cause kidney problems as well as bleeding it the gastrointestinal system (e.g. Stomach). ...Read more

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What happens when someone takes too much aleve (naproxen)?

Serious problems: He or she can end up with serious toxicity from the med including ulcers, GI bleeds and compromise of kidney function. ...Read more

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Can I take Aleve and cephalexin together?

Can I take Aleve and cephalexin together?

Sounds ok: A person who has no problems taking naproxen (Aleve) by itself, and who has no problems taking cephalexin (Keflex) by itself, should also have no problem taking Aleve and cephalexin together. The two medications do not have noticeable interactions with one another. ...Read more

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Is it ok to take aleve, while on zoloft (sertraline)?

Drug interactions: There is a possible drug interaction. Per Drugs. Com drug interaction checker- "Using sertraline together with naproxen may increase the risk of bleeding. The interaction may be more likely if you are elderly or have kidney or liver disease". That does not mean you shouldn't take them both - but be aware of that risk. ...Read more

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Can I take aleve for my back pain if I took hydroxyzine?

Can I take aleve for my back pain if I took hydroxyzine?

Just plain aleve: Is fine with hydroxyzine. Not aleve pm or other combo aleve preparations ...Read more

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Can I take Aleve sinus and cold with tamiflu (oseltamivir)?

Yes you can: It is safe. However, take it with food or proton pump inhibitors (prilosec) to prevent potential stomach pain. ...Read more

Naproxen (Definition)

Naproxen is a non-steroidal anti-inflammatory drug. It inhibits cyclooxygenase thus reducing ...Read more


Dr. Heidi Fowler
888 Doctors shared insights

Aleve (Definition)

Aleve ...Read more