Doctor insights on:
Can I Donate Blood If I Have Alpha Thalassemia Trait
My 3yr old daughter has an Alpha thalassemia trait which i found she inherited from me. We're the same blood type could that have been the reason?
Inheritance: Both are inherited characteristics and are simply due to the fact that you are her mother (and were also affected by the father)...they aren't "linked" together. Thalasemias are due to production defects in hemoglobin, the oxygen carrying part of your red blood cells. Blood type (A, B, O) is due to carbohydrate groups on the red cells. Whichever type you have is your blood type. ...Read more
Safe if necessary: Blood transfusions are given only when necessary especially in the younger population or blood disorders. Transfusions are necessary for major bleeding resulting in shock, low blood pressures, or continued blood loss. All transfusions are screened and safe but there is always a 1-3% risk of a clerical error. Pts. With blood disorders face increased risk of blood transfusion reactions. ...Read moreSee 1 more doctor answer
I have alpha thalassemia trait. Are there programs I can do to train myself to run a race without passing out or getting too fatigued?
Like normal...: A person with Alpha thalassemia trait (two mutated Alpha chain genes and two normal) usually has no symptoms. You may be slightly anemic, but this should not affect your exercise performance. Perhaps if you were running ultra marathons in the alps you might see an effect, but otherwise you should be able to train normally and do great. Regardless of Alpha thal trait, stay hydrated. ...Read moreSee 1 more doctor answer
No: People with Alpha thalassemia trait are similar to regular people. Some Alpha thal. Trait persons are mildly anemic, but the anemia is not enough to cause symptoms. A few people may be anemic enough to feel tired or have pallor (pale appearance). Intestinal problems, and other medical problems, can occur just as they occur in non-thalassemic persons. ...Read moreSee 1 more doctor answer
Not quite: Normal people have 4 Alpha globulin genes. Mutations in 1, 2, 3, or all 4 of the genes cause the 4 levels of Alpha thalassemia. One mutation = silent carrier (no symptoms), 2 mutat. = Alpha trait (mild anemia), 3 mutat. = HGB h disease (anemia sometimes needing transfusions), 4 mutat. = bart's disease (fatal before birth in almost all cases; lifelong transfusions needed to survive if born alive). ...Read moreSee 1 more doctor answer
Inherited defect: Our regular hemoglobin is composed of Alpha and beta chains that come together to form working hemaglobin. Alpha thalassemia trait occurs when a person inherits a defective Alpha chain gene from one parent & a normal Alpha chain gene from the other. This causes some reduction in Alpha chain production with resulting mild anemia. ...Read more
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