Doctor insights on:
Can Hypothyroidism Turn Into Thyroid Cancer
No: A true thyroid adenoma is a benign tumor. However, this can only be accurately assessed once it has been removed surgically -- not by fine needle aspiration. There are molecular alterations seen in carcinoma than are not seen in adenoma. However, some of the molecular changes are cumulative, like p53 mutations -- which are expressed in higher frequency in cancer. ...Read moreSee 2 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Least of worries: Hyperparathyroidism is quite common (one person in 1000 will get it during a lifetime) and makes a person quite ill. About 1% of these cases are caused by a tumor that's already cancer -- usually not super-aggressive -- and this is one reason to operate sooner rather than later. If you are hyperparathyroid, know all your options -- some folks do choose observation. ...Read more
No: Thyroid cancer is fairly common, the most common endocrine malignancy, and therefore, it can be seen in the setting of thyroid dysfunction (most commonly, hashimoto thyroiditis), but thyroid dysfunction has never been shown, to my knowledge, to cause thyroid cancer. ...Read moreSee 1 more doctor answer
Yes, in some cases: Anytime there is chronic inflammation in a part of the body, that increases cell turnover and the risk of cancer is increased. This is true of most organ systems in the body. The relative risk depends on many things, such as the specific nature of the thyroid disorder, how it was/is treated and whether or not there is ongoing inflammation in the gland. I suggest discussing this with endocrinology. ...Read more
Rarely: Adenomyosis is mis-placed endometrial lining glands into the wall of the uterus (into the muscle). It is uncommon for these misplaced glands to become malignant, but it does happen. More often, it is the surface glands that undergone malignant transformation, and then grow down and into the areas of adenomyosis. At your age, this would be exceptionally rare. ...Read moreSee 1 more doctor answer
Can metastatic papillary thyroid cancer spread to the parathyroid? Is this rare? Can recurrent pap thyroid cancer show up on parathyroid?
parathyroid: Presumably you have had surgery followed by radioactive iodine. This could damage the parathyroid and cause hypoparathyroidism, although this usually does not happen. Thyroid cancer spreads locally (within the neck), and that could damage the parathyroids more, but again, this does not usually happen. Check this out with your endocrinologist. ...Read more
Very Unlikely: Fibroadenomas are benign tumors of the breast. They are quite common and are not precancerous. Very rarely there have been cases reported where a fibroadenoma has been thought to turn into a tumor called a cystosarcoma phyllodes of the breast which is a very unusual type of breast cancer. ...Read more
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