Doctor insights on:
Can Getting A Pancreas Transplant Solve The Problem Of Pancreatic Cancer
Transplant for ca: No. Pancreas transplantation is for type 1 dm, usually with a kidney transplant.. If you have pancreas cancer and are a candidate for resection, then this can be accomplished and the pancreas does not need to be replaced. The last thing you would want while dealing with a pancreas cancer is the requirement for immunosuppression, which would encourage cancer growth. ...Read moreSee 3 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
They don't work: Pancreas transplants aren't used to treat pancreatic cancer. Although it seems like it might work, it doesn't. Why? When pancreatic cancer is diagnosed, cancer cells have usually spread to other places in the body, like seeds that have dispersed. Pancreas transplants are used for people with diabetes, but not as a treatment for pancreatic cancer. We need better treatments for pancreatic cancer! ...Read moreSee 2 more doctor answers
First an evaluation: Call one of the local transplant centers in your location and make an appointment to be evaluated. You can contact the american society of transplant surgeons for a center in your area. Not every diabetic is a good candidate for the procedure and you will need careful evaluation and discussion of benefits and risks. ...Read more
Panc tx alone: The majority of recipients get a kidney either simultaneously or before a pancreas transplant, but there is a group that get just a pancreas. Usually for very brittle, potentially life threatening dm1, almost always with hypoglycemia unawareness and frequent emt or er visits. Also well described following total pancreatecomy for non-malignant disease. ...Read moreSee 4 more doctor answers
For what reasons won't a doctor attempt a liver transplant in a stage IV pancreatic cancer patient?
Problematic: Generally if pancreas cancer has traveled to the liver, then there is too much disease to expect benefit of a liver transplant. If the original cancer in the pancreas is still present, then the liver transplant will not help. Medications to lower the immune system to allow for an organ transplant will also cause cancer in other sites (such as in the pancreas) to rapidly grow further. ...Read more
Pancreas transplant: There are two common indications for a pancreas transplant: 1. A commitment to lifelong immunosuppresion for another organ transplant in a type 1 diabetic (usually a kidney for diabetic nephrology, but liver and lung have been done as well) or 2. Very poorly controlled type 1 diabetes despite optimized medical care. This usually requires documented episodes of hypoglycemia unawareness. ...Read moreSee 3 more doctor answers
Catch 22 answer: With successful transplantation and a robust recipient, there should not be any left over disability. The patient should be capable of working within approximately 2-3 months. But many diabetics who need these transplants have serious visual and foot problems that cause permanent disabilities. When possible, the point of transplant is full return to all of life. The judgement is made individually. ...Read more
Call local center: There are two common indications for a pancreas transplant: 1. A commitment to lifelong immunosuppresion for another organ transplant in a type 1 diabetic (usually a kidney for diabetic nephrology, but liver and lung have been done as well) or 2. Very poorly controlled type 1 diabetes despite optimized medical care. This usually requires documented episodes of hypoglycemia unawareness. ...Read moreSee 2 more doctor answers
Toned down: 1st of all, the quality of life and overall health of most pancreatic transplant patients are dramatically better than their pre transplant state. That being said, unless you have a perfect match, immuno suppressants are needed for you to live with the transplanted organ. Your immunity will not be optimal but should be manageable if you take proper precautioins. ...Read moreSee 1 more doctor answer
When would you recommend an islet cell transplant? Why would a patient be given an entire pancreas transplant?
DEPEND ON THE PATIEN: ISLET CELL TRAMSPLANT INDICATIO VARRIED, AND PATIENT SELECTION DECIDED BY A SPECIALIST. PANCRATIC TRAMSPLANT FIRST REQURED EITHER LIVE DONOR FOR PARTIAL PANCRAS TRANSPLANT OR A CADAVRE DONOR FOR A FULL TRANSPLANT, THE NUMBER OF AVAILBLE ORGAN VERY LIMITED COMARING TO THE NEED, SURGERY IS VERY COMPLEX FOR LIVE DONOR AND CARRY SIGNIFUCANT RISK TO THE DONOR AND RECIPIENT.AND REJECTION IS MUCH HIGHER. ...Read more
In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more
Type 1 diabetics do not make insulin, but if they get a transplant, the new pancreas would make Insulin and the sugars would be normal. It is like having a biologic Insulin pump that works perfectly. It is not a cure, but it is currently the most effective treatment available. The downside: it involves a big operation, lifelong immunosuppresion and is only ...Read more
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