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Doctor insights on: Can Diphenhydramine And Oxymetazoline Hydrochlorde Be Taken Together

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I have a horrible headache from sinus pressure I tried afrin nose spray and Benadryl (diphenhydramine) at night. I feel terrible? Would I benefit more from sudafed?

I have a horrible headache from sinus pressure I tried afrin nose spray and Benadryl (diphenhydramine) at night. I feel terrible? Would I benefit more from sudafed?

Maybe: It would be better to see some one for your problem. Afrin spray and benadryl (diphenhydramine) or not the best remedies for sinus complaints. Sudafed may help better, but you should see your physician to make sure that you are treating the right problem. ...Read more

Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Can Azo and Benadryl (diphenhydramine) be taken together?

Can Azo and Benadryl (diphenhydramine) be taken together?

Azo??: Please be more specific regarding the name of the first medication. ...Read more

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Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

No: I am not sure what l-theanine is. However, the only dietary supplements/herbals I know of which should be avoided when taking Diphenhydramine are valerian, st. John's wort, kava kava, and gotu kola; as the combination may enhance CNS depression. I am doubtful that whatever l-theanine is will compound any sedative effects you may experience with Diphenhydramine alone. ...Read more

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Can allegra and Benadryl (diphenhydramine) be taken together?

Can allegra and Benadryl (diphenhydramine) be taken together?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). ...Read more

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Can Benadryl (diphenhydramine) and Claritin be taken together?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. ...Read more

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Can you Claritin and Benadryl (diphenhydramine) be taken together?

Can you Claritin and Benadryl (diphenhydramine) be taken together?

Yes: Most antihistamines are dosed at levels much below the toxic levels. Claritin was initially tested in drug studies at 4 times the current recommended dose. These same studies found that 10 mg yielded nearly equvalent effects as 40 mg. Since there is not a dramatic dose effect, increasing to higher levels rarely improves nasal symptoms. Benadryl (diphenhydramine) may have drying effects but sedation limits the dose. ...Read more

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Help can Benadryl (diphenhydramine) and enalapril react if taken together?

Help can Benadryl (diphenhydramine) and enalapril react if taken together?

Not likely: Although all medication may interact, there is not a frequent or known interaction between an ACE inhibitor (enalapril) and antihistamine (benadryl).
Careful with driving when you take antihistamines during day time ...Read more

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What would happen if someone takes a Benadryl (diphenhydramine) & 5mg vicdion together?

More sleepy: Nothing serious at these low doses although you may feel more sleepy since the sedation effects of ech medicine add up. But it should be fine after 12-18 hours. ...Read more

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Can I take Benadryl (diphenhydramine) and nyquil together?

You can, but: Not recommended due to drug interactions. Both drugs increase sedation and drowsiness. ...Read more

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Can u take Benadryl (diphenhydramine) and pennicillin together?

Can u take Benadryl (diphenhydramine) and pennicillin together?

Yes: You can take them both best with food. Be aware however Benadryl (diphenhydramine) may make you very drowsy. Extreme caution if you drive. Or better yet, don't drive! ...Read more

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Can I take a benadryl (diphenhydramine) & Mucinex night together?

Can I take a benadryl (diphenhydramine) & Mucinex night together?

Yes: Benadryl (diphenhydramine) will help you sleep and help with excess mucus production. Mucinex (guaifenesin) is called an expectorant as it helps thin and loosen mucus to make your cough more effective at clearing the mucus from your lungs. There should be no problem taking these two medications together. ...Read more

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Is it safe to take ambient and Benadryl (diphenhydramine) tigether?

Is it safe to take ambient and Benadryl (diphenhydramine) tigether?

Check with doc: Both cause sleepiness so combined makes even more so. Both can hurt you if you take too much, alone or together. It also depends on what other meds, drugs/alcohol, caffeine, you're taking & why you need the med in the first place. Good sleep is often obtained through good habits, and enough daily exercise & proper diet, to ensure a sound sleep. I bet a lot of marathon runners were ex-insomniacs! ...Read more

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Can melatonin and Benadryl (diphenhydramine) be mix and safe to use together?

Yes: But both have sedative properties and can lead to some hangover effects in the morning if taken for sleep, take as low a dose of melatonin as possible, 90min before desired sleep time. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Heidi Fowler
190 Doctors shared insights

Oxymetazoline (Definition)

Oxymetazoline is a nasal preparation which is a kind of ...Read more