Doctor insights on:
Can Diphenhydramine And Oxymetazoline Hydrochlorde Be Taken Together
I have a horrible headache from sinus pressure I tried afrin nose spray and Benadryl (diphenhydramine) at night. I feel terrible? Would I benefit more from sudafed?
Azo??: Please be more specific regarding the name of the first medication. ...Read more
Yes: Both can be sedating so be careful. There is no reason they can not both be used. ...Read more
Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?
No: I am not sure what l-theanine is. However, the only dietary supplements/herbals I know of which should be avoided when taking Diphenhydramine are valerian, st. John's wort, kava kava, and gotu kola; as the combination may enhance CNS depression. I am doubtful that whatever l-theanine is will compound any sedative effects you may experience with Diphenhydramine alone. ...Read more
Yes: Most antihistamines are dosed at levels much below the toxic levels. Claritin was initially tested in drug studies at 4 times the current recommended dose. These same studies found that 10 mg yielded nearly equvalent effects as 40 mg. Since there is not a dramatic dose effect, increasing to higher levels rarely improves nasal symptoms. Benadryl (diphenhydramine) may have drying effects but sedation limits the dose. ...Read more
More sleepy: Nothing serious at these low doses although you may feel more sleepy since the sedation effects of ech medicine add up. But it should be fine after 12-18 hours. ...Read more
Yes: No problem there.Get a more detailed answer ›
Ambien (zolpidem): More sedation, otherwise ok.Get a more detailed answer ›
Yes: Benadryl (diphenhydramine) will help you sleep and help with excess mucus production. Mucinex (guaifenesin) is called an expectorant as it helps thin and loosen mucus to make your cough more effective at clearing the mucus from your lungs. There should be no problem taking these two medications together. ...Read more
Check with doc: Both cause sleepiness so combined makes even more so. Both can hurt you if you take too much, alone or together. It also depends on what other meds, drugs/alcohol, caffeine, you're taking & why you need the med in the first place. Good sleep is often obtained through good habits, and enough daily exercise & proper diet, to ensure a sound sleep. I bet a lot of marathon runners were ex-insomniacs! ...Read more
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