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Doctor insights on: Can Cvid Cause Extreme Fatigue And Aching Joints

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

Dr. Stratos Christianakis
1,189 Doctors shared insights

Joints (Definition)

Joints are parts of the body, formed by the cartilage-covered ends of bones plus the strong, flexible ligaments that attach the bones to one another. Movements at the joints in the body allow the different parts of the body to move in ...Read more


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Can cvid cause extreme fatigue and aching joints?

Can cvid cause extreme fatigue and aching joints?

Futher Investigation: Most definitely. However, immune deficiencies can also be linked to autoimmune diseases so further testing for things like inflammatory arthritis and connective tissue diseases is important. ...Read more

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Severe body/joint aches, hobbling after being seated, extreme fatigue, onset 2 months ago, hysterectomy 1 yr ago?

Severe body/joint aches, hobbling after being seated, extreme fatigue, onset 2 months ago, hysterectomy 1 yr ago?

Need more info: Fatigue, myalgia, arthritis could be a result of a rheumatic disorder such as lupus or rheumatoid arthritis. Has nothing to do with your hysterectomy, although following your hysterectomy you might need estrogen. You need to see your primary care physician and have some blood work to include sed rate, RA titer, FANA as a screening ...Read more

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What could cause joint and body pain, sore throat, and extreme tiredness for 5 weeks?

What could cause joint and body pain, sore throat, and extreme tiredness for 5 weeks?

Many possibilities: There are a lot of possibilities that could cause your symptoms including: viral illness like mono syndromes (ebv and cmv), possibly mosquito-borne illnesses like west nile, etc., collagen-vascular diseases, valley fever (cocci), histoplasmosis, leukemia or other cancers. Get yourself checked out asap. ...Read more

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Hi I'm 21 I exclusively breastfeed and its been 3 months I have daily bone and joint aches, extreme fatigue and hot flashes what can this be?

Hi I'm 21 I exclusively breastfeed and its been 3 months I have daily bone and joint aches, extreme fatigue and hot flashes what can this be?

Hot flashes: Congrats on a new baby.
Breast feeding may be tough but gets easier over time.
For now you should make an early appointment to see your obstetrician. I am confident that she/he will help you feel better.

The bone and joint aches might be arthritis but I don't think that is the case. Bring that to your obstetricians attention. ...Read more

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All over joint pain especially shoulder neck lower back. Severe head aches extreme fatigue. Numbness tingling fingers and toes about 6 months?

All over joint pain especially shoulder neck lower back. Severe head aches extreme fatigue. Numbness tingling fingers and toes about 6 months?

Be seen: You may need to be seen as there are multiple possibilities. Numbness suggests neurological origin. May be more than one condition going on. A thorough exam and appropriate studies would likely reveal the cause or causes. ...Read more

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I have had extreme fatigue, swollen tonsils, constant headache, joint/ muscle aches, and red but not super sore throat. My boyfriend has mono, do i?

I have had extreme fatigue, swollen tonsils, constant headache, joint/ muscle aches, and red but not super sore throat. My boyfriend has mono, do i?

Mono: The symptoms you described combined with a known contact (your boyfriend) with mono makes it very likely that you have it as well. You should see your primary care doctor for an exam and tests to confirm a diagnosis. ...Read more

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Joint swelling, fatigue, and strep? How often does strep cause joint swelling or joint aches?

Joint swelling, fatigue, and strep? How often does strep cause joint swelling or joint aches?

Not often if treared: Strep infection may lead to other inflammatory illnesses, including:
scarlet fever, an illness characterized by a rash
inflammation of the kidney (poststreptococcal glomerulonephritis)
rheumatic fever, a serious condition that can affect the heart, joints, nervous system and skin

the risk of developing severe complications from strep throat is low in the United States. ...Read more

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I have hives, joint aches, extreme coldness and fatigue....do I have an autoimmune disease? I am a 31 year old female who is extremely active

I have hives, joint aches, extreme coldness and fatigue....do I have an autoimmune disease? I am a 31 year old female who is extremely active

?: The symptoms you listed can just be due to viral illness, or a reaction to a medication you are on or received lately, or something else more common than an autoimmune disorder, given that you sound healthy otherwise, kindly visit your doctor, present your concerns, it is much easier to rule out an autoimmune disease than to confirm it, wish you wellness, ...Read more

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17yr old had an iron infusion 6 days ago, still extreme tiredness, nausea has only been able to eat small amounts and sore joints. Is this normal?

17yr old had an iron infusion 6 days ago, still extreme tiredness, nausea has only been able to eat small amounts and sore joints. Is this normal?

IV iron: Even with full replacement of low iron stores, it can take up to a month to make 2-3 pints of blood so I suspect that is why your teen is still tired. The nausea and joint pains are symptoms which can be seen following the administration of IV iron. Please notify your teen's md about these symptoms so they can determine whether or not something serious is going on. ...Read more

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On augmentin (amoxicillin and clavulanate) for 10 days last dosage yesterday. Can this cause fatigue, muscle aches, joints to hurt, anxiety- been reading nasty stuff from patients?

On augmentin (amoxicillin and clavulanate) for 10 days last dosage yesterday. Can this cause fatigue, muscle aches, joints to hurt, anxiety- been reading nasty stuff from patients?

Need more info: This is not likely to be due to augmentin, (amoxicillin and clavulanate) but allergic reactions may take strange forms. The question is why were you on antibiotics, was the diagnosis correct, do you have something else going on at the same time, etc.? If this keeps up please go see a good family practitioner or internist and get diagnosed and treated. Good luck. ...Read more

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Terrible spasms in ribs at night, spine stiff, hips ache, feet numb and burn, major joints ache, double vision, right foot drag, fatigue. Causes?

Terrible spasms in ribs at night, spine stiff, hips ache, feet numb and burn, major joints ache, double vision, right foot drag, fatigue. Causes?

Neuromuscular issues: It sounds like you need a thorough work-up to make clear the cause of these symptoms. Seeing a neurologist might be a good place to start - or if you have a bright family doctor who can at least get the 'ball rolling'. There are different possibilities that come to mind including Lyme disease, vitamin B12 deficiency, MS, uncontrolled diabetes, heavy metal poisoning, and more -hope you get help. ...Read more

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Right upper abdomen tender to touch, bloated stomach, rash on stomach, extreme tiredness, night sweats, sore knee joints?

Right upper abdomen tender to touch, bloated stomach, rash on stomach, extreme tiredness, night sweats, sore knee joints?

See below: This is a problem that necessitates a face-to-face meeting with your doctor. This will allow him/her to examine you, ask specific questions. And possibly order tests to find out what's wrong and what to do to help you. ...Read more

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I have had moderate body and joint aches for more than 24 hours with no fever or fatigue. I am 33 with no health problems.

I have had moderate body and joint aches for more than 24 hours with no fever or fatigue. I am 33 with no health problems.

Would wait and see: If you have no significant health problems, it may be a viral syndrome. These are usually self limited and will pass as you overcome the infection. If it continues for more than half a week with no improvement, see a doctor to get blood tests done. ...Read more

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I have fatigue, sore joints, weakness, and back pain. What could be wrong?

Lots of potential: There are a lot of potential causes. I recommend you see a primary care doctor asap. ...Read more

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Normal body temp, then suddenly drop from 98.6 to 97.0. Shivering, joint ache, extremely fatigue feeling. No appetite.?

Normal body temp, then suddenly drop from 98.6 to 97.0. Shivering, joint ache, extremely fatigue feeling. No appetite.?

Infection!: A low temp can indicate in infection, like a high temp. You are definitely sick, can't tell how serious it is from here! See or call your doc today. ...Read more

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I am finding stretching is helping my muscle / joint pain & aches. As well as some fatigue - what is the link to that? Why does stretching help

I am finding stretching is helping my muscle / joint pain & aches. As well as some fatigue - what is the link to that? Why does stretching help

Stretching is: Stretching is exercise and warms you up! Consider that your ligaments & tendons are 1 /10 saturated fat. Stretching warms up this fat by increasing blood flow. This liquefies fats. You move with less pain, & more important, less chance of injury! ...Read more

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Husband has been extremely fatigued/tired for months. 49, not as interested in sex. Joints ache, sleeps 10 hours at night and has to nap afternoon.??

Husband has been extremely fatigued/tired for months. 49, not as interested in sex. Joints ache, sleeps 10 hours at night and has to nap afternoon.??

Medical checkup: A good medical checkup would probably be a good start. Many potential causes from problems with sleep itself like sleep apnea to hormonal problems like low testosterone, to metabolic problems. Discuss with your medical doctor. ...Read more

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Aching joints, lethargy, stiff neck. What condition could this be?

Many possibilities: Arthritis conditions, Lyme disease, viral infections, depression, sleep disorders. Probably need to start with your Family Doctor for work up. ...Read more

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Period like symptoms after period has ended since July 12th. Queasy, joint aches, fatigue, no appetite.

Primary care: That are quite a few symptoms in a variety of body systems. Consider doing a virtual visit with a HEALTHTAP Prime doctor to help narrow down the possible causes. Blood tests such as thyroid and anemia can be done through healthtap as well. ...Read more

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Ana direct= positive, rnp= 1.9, crp=neg, sedr=neg, rf=neg, sm anti=neg, all other labs neg. Slight fatigue and mild joint aches. What does this mean?

Ana direct= positive, rnp= 1.9, crp=neg, sedr=neg, rf=neg, sm anti=neg, all other labs neg. Slight fatigue and mild joint aches. What does this mean?

Impossible to say: An ANA screen by itself has no significance. With symptoms that vague there is no way to know without a thorough evaluation. See a rheumatologist for this issue. ...Read more

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I feel sick to my stomach for weeks at a time. Along with the nausea, I get headaches, joint aches, pain throughout my body, foggy thinking & fatigue?

Tough to know: Could be as straight forward as vitamin deficiency or as complicated as mast cell activation disorder. Consider a virtual consult to discuss more about the nature and timing of symptoms and context of your medical history. I hope you find relief soon! ...Read more

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My joints are sore stiff and I'm fatigue I feel like a old lady and only 29! any ideas? Normal X-ray but pos ANA and high esr

My joints are sore stiff and I'm fatigue I feel like a old lady and only 29! any ideas? Normal X-ray but pos ANA and high esr

Need Rheumatologist: You have positive ANA test and elevated ESR and have pain in joints. You need to consult a rheumatologist if not already done to make a proper diagnosis and get treated appropriately. You may have one of the autoimmune condition and may need further testing to make the diagnosis. Consult a rheumatologist. ...Read more

Dr. Bruce Weisbrot
121 Doctors shared insights

Joint Aches (Definition)

Discomfort emanating from the connection between two bones ...Read more


Dr. Rita Corona
397 Doctors shared insights

Exhaustion (Definition)

Exhaustion = depletion of energy which can occur ...Read more