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Doctor insights on: Can Amoxicillin Make You Tired

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On day 4/5 taking 500mg amoxicillin 3 times a day. Can't wake up in mornings, extreme tiredness, is this side affect?

On day 4/5 taking 500mg amoxicillin 3 times a day. Can't wake up in mornings, extreme tiredness, is this side affect?

No. Something's up.: Tiredness isn't a common side effect of amoxicillin; it could be a residual from whatever infection amoxicillin was trying to treat, or it could represent some other problem unrelated or indirectly related to amoxicillin (for instance, kidney damage causing an electrolyte imbalance). In any case, you should talk to the doctor who prescribed amoxicillin for you or use HealthTap Prime to get answers ...Read more

Amoxicillin (Definition)

Amoxicillin is in the penicillin class of antibiotics. All penicillins are distinguished by the presence of a beta-lactam ring, and are known to kill bacteria by inhibiting synthesis (production) ...Read more


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Is it possible that amoxicillin make me feel tired?

Is it possible that amoxicillin make me feel tired?

No: No. That is not recognized side effect. But assuming you are taking it because you are ill, the illness may be affecting you. ...Read more

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Please tell me, could amoxicillin make me tired and not want to eat?

Yes: Either alone or interaction with other medications. Call your physician especially if you have other symptoms like a rash or difficulty breathing or swallowing or any severe dizziness or nausea/vomiting. ...Read more

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I am recovering from two weeks of cold/sinus symptoms and taking amoxicillin. I'm tired, but I want to exercise. Is it better for me to rest?

I am recovering from two weeks of cold/sinus symptoms and taking amoxicillin. I'm tired, but I want to exercise. Is it better for me to rest?

Sinus: Your body tells you, exercise can be refresshing but if your head is hurting when you bend down or you are coughing, you probably need to give it some rest until you fully recover. ...Read more

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I am on amoxicillin (875 mgs) for a sinus infection and after taking it, I can't help but feel really tired. Can the medication cause this?

I am on amoxicillin (875 mgs) for a sinus infection and after taking it, I can't help but feel really tired. Can the medication cause this?

Fatigue: Any medications may have very mild or significant side effects. Serious side effects such as anemia, liver or kidney toxicity may in turn cause significant fatigue. Infection by itself can make you feel tired also. See your doctor for screening blood work if your fatigue symptoms persist or worsen dramatically ...Read more

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I was given amoxicillin for a sinus infection. The medication worked, but when I ran out, I feel facial pain and fatigue again. What should I do?

Sinusitis: Hello. It sounds like your sinusitis is still present. Another round of antibiotics may be needed. Also a different antibiotic with better coverage for resistant bacteria may help resolve your infection. If that doesn't resolve your infection then an ENT evaluation may be needed. Good luck. ...Read more

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I'm currently on metronidazole 400g 3 tablets a day and amoxicillin 500g 6 tablets a day, I'm on these due to a infection, I feel tired an drowsy?

I'm currently on metronidazole 400g 3 tablets a day and amoxicillin 500g 6 tablets a day, I'm on these due to a infection, I feel tired an drowsy?

Not sure what type: Of infection you are treating with the above antibiotics, but chances are your symptoms may be more related to the disease course than the actual antibiotics. Metronidazole is known to cause some GI symptoms including nausea and vomiting, anorexia and fatigue, so it is possible that you are feeling effects of that drug. Thanks for trusting in HealthTap. ...Read more

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Can augmentin (amoxicillin and clavulanate) cause severe fatigue and weakness?

Can augmentin (amoxicillin and clavulanate) cause severe fatigue and weakness?

Yes: Augmentin (amoxicillin and clavulanate) can change the microbial makeup of the GI tract and can lead to diarrhea and potentially loss of essential electrolytes, fluids and nutrients.
These then can cause fatigue and weakness. ...Read more

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Have an URI for 3 weeks on augmentin (amoxicillin and clavulanate) for 6 days still feeling tired and lousy is this normal?

Have an URI for 3 weeks on augmentin (amoxicillin and clavulanate) for 6 days still feeling tired and lousy is this normal?

URI: It can take a lot out of you, if you finish your course and you still feel bad you need to tell your doctor for further treatment and investigation of your symptoms. ...Read more

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I am experiencing cough (more at night), fatigue, left swollen tonsil and excess saliva. Doc put me on amoxicillin, had this for over a week?

Virus? Allergy?: Most illnesses like this are due to common respiratory viruses or allergies, and these do not respond to any kind of antibiotic. Perhaps amoxicillin was worth a try, but no surprise it hasn't helped. Check back with the doctor treating you. Good luck! ...Read more

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My son finished amoxicillin 4 days ago. Yesterday he woke up with fatigue & body aches + headache. This morning the rash subsided but now vomiting?

My child is ill: This very well may be a reaction or side effect in the GI tract of the antibiotic. If your child is improving then we have time to wait and watch. But, if there is any fever, increasing lethargy or unresponsiveness you may want to call your doctor on call. ...Read more

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I am experiencing toothache. The following also describe me: Headache, Fatigue, and Swollen face. Need penicillin not amoxicillin. Medicare and disa?

I am experiencing toothache. The following also describe me: Headache, Fatigue, and Swollen face. Need penicillin not amoxicillin. Medicare and disa?

Meds: Amoxicillin is penicillin. Antibiotics will NOT cure infected tooth, only slow spread and severity of infection. Probably need extraction or root canal treatment. You need to see your Dentist before meds run out. ...Read more

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Fatigue, malaise, weight loss, low grade fever. ASO screen >400. On oral amoxicillin, 10 days. No better. What needs to be checked next? What tests?

Strep test: Did you have earlier ASO titer which then documented rise of ASO? If you truly had strep infection which was not sensitive to Amoxil (amoxicillin) there are plenty of others available. Your doc should speak to the ID maven at your local hospital and ask for advise on treatment in your particular zone. ...Read more

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Have URI went to doc on augmentin (amoxicillin and clavulanate). I am on my 6 day still feeling lousy and so tired is this normal?

Have URI went to doc on augmentin (amoxicillin and clavulanate). I am on my 6 day still feeling lousy and so tired is this normal?

Virus: You more than likely have a viral respiratory illness and the antibiotic will not change its course, only add symptoms from its side effects. Symptom management, hydration and rest should help you recover more quickly. Recheck with your dr if not improving in next couple days. ...Read more

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Finished full amoxicillin dose for sinus infection. 2 days after have nausea and diarrhea. Also abnormally tired. Medication side effects?

Finished full amoxicillin dose for sinus infection. 2 days after have nausea and diarrhea. Also abnormally tired. Medication side effects?

See a doctor: Diarrhea after taking a course of antibiotics could indicate a serious infection. I recommend you see a doctor. ...Read more

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29 yr. Old male with history of hypothyroid & has severe head cold and chest congestion since dec. Muscle weakness and fatigue. Is amoxil (amoxicillin) best route?

29 yr. Old male with history of hypothyroid & has severe head cold and chest congestion since dec. Muscle weakness and fatigue. Is amoxil (amoxicillin) best route?

Not cold: "a cold" it is generally meant to refer to a viral upper respiratory infection or uri. This is a self limited infection which means it gets better on its own in 1-2 weeks. When respiratory symptoms have persisted for this long it's time to look for another explanation. See a doctor who can take some time, and follow up. ...Read more

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I was on prevpac (lansoprazole amoxicillin and clarithromycin) for 2 weeksand omeprazole 80mg perday for a week. It's been 3 days I stopped, now feeling tired and aches. Is that withdrawal of ppi?

I was on prevpac (lansoprazole amoxicillin and clarithromycin) for 2 weeksand omeprazole 80mg perday for a week. It's been 3 days I stopped, now feeling tired and aches. Is that withdrawal of ppi?

Not usually: Prevpac (lansoprazole amoxicillin and clarithromycin) was to treat bacteria in your gut and adjust acid level. Gi system goes through an adjustment with these powerful meds, sometimes just the change of stopping them can contribute to symptoms described. Should improve. ...Read more

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On augmentin (amoxicillin and clavulanate) for 10 days last dosage yesterday. Can this cause fatigue, muscle aches, joints to hurt, anxiety- been reading nasty stuff from patients?

On augmentin (amoxicillin and clavulanate) for 10 days last dosage yesterday. Can this cause fatigue, muscle aches, joints to hurt, anxiety- been reading nasty stuff from patients?

Need more info: This is not likely to be due to augmentin, (amoxicillin and clavulanate) but allergic reactions may take strange forms. The question is why were you on antibiotics, was the diagnosis correct, do you have something else going on at the same time, etc.? If this keeps up please go see a good family practitioner or internist and get diagnosed and treated. Good luck. ...Read more

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I've had watery lungs chronic cough fatigue + mucus in sputum-1/1/14. I've taken augmentin (amoxicillin and clavulanate) and prednisone. Recurring cold sxs. I've seen 2 drs. Help!

I've had watery lungs chronic cough fatigue + mucus in sputum-1/1/14. I've taken augmentin (amoxicillin and clavulanate) and prednisone. Recurring cold sxs. I've seen 2 drs. Help!

Many possibilities: A chest x-ray and a ct sinus may give a clue as to infectious etiologies. If your symptoms continue a visit to an allergist, pulmonologist or ENT may be in order. Some viruses can cause a chronic cough for months after the initial infection. ...Read more

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Tired. Feverish. Fatigue. Weakness. Sore throat. These are the symptoms. It's been 3 weeks. Nothing improved…I've tried Zithromax, amoxicillin, etc…?

Tired. Feverish. Fatigue. Weakness. Sore throat. These are the symptoms. It's been 3 weeks. Nothing improved…I've tried Zithromax, amoxicillin, etc…?

Not bacterial: Clearly no bacterial infection is the cause of these symptoms. Stop trying antibiotics; they won't help. See a doctor if your symptoms continue or you remain concerned. ...Read more

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Sore throat, headache, neck pain, malaise, & fatigue x15 days. Neg. Strep test, no fever. Taking amoxicillin w/no help. Possible causes?

Needs work-up: For symptoms that are ongoing like that- I think of several possibilities. One would be mono- and that's an easy one (mono-spot test). Not sure if you have risk factors for HIV but I would test you for that too. Other viruses such as enterovirus or adenovirus could cause these symptoms, but usually not this long. REST may help you. Would check back with doc prescribing Amoxicillin-probably stop it ...Read more

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I am experiencing chronic cough, painful sore throat, fatigue, runny nose and difficulty speaking. Have been on amoxicillin 500mg with no help.?

I am experiencing chronic cough, painful sore throat, fatigue, runny nose and difficulty speaking. Have been on amoxicillin 500mg with no help.?

Resistant Organism: Hi TomS,
You have been on amoxil 500 w no improvement of chronic cough, sore throat, fatigue, runny nose.
You many have a virus in which antibiotics can not cure.
You many have a resistant organisim which needs a different antibiotic. Give a call to doctor. They can prescribe again or tell you its a virus and will run its course.
Dr Lori Lange-Pennsylvania ...Read more

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Chronic autonomic, circulatory, and neuropsychiatric symptoms after having a AGE-type of illness in 2014, in a 33 year-old woman.....?

Chronic autonomic, circulatory, and neuropsychiatric symptoms after having a AGE-type of illness in 2014, in a 33 year-old woman.....?

Perhaps I can: Offer some quite speculative but hopefully helpful comments. The only sense I can make of your question is if you mean IgE, or immunoglobulin E. Autoimmune disorders occur when the immune system mistakes body cells for harmful invaders and reacts to them. Reversing or controlling the process is very challenging; the immune reaction may be controlled but rarely eliminated. Keep working with your Doc ...Read more

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Take amoxillin 500 antibiotics. Cause me nosebleeding and make me very tired. Should I stop to take it?

Not from Medication: The fatigue and nose bleeds are probable from your body fighting infection and not from amoxicillin, see your Doctor right away and don't blame the medicine, it is always something else!! ...Read more

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Feeling unwell after strep infection - I am still feeling a bit weak and very tired after a strep infection. I have 2 days of amoxicyllin left?

Feeling unwell after strep infection - I am still feeling a bit weak and very tired after a strep infection. I have 2 days of amoxicyllin left?

Revisit your doctor.: Typically we doctors are trained to think of one disease--one diagnosis. However, the longer I practice medicine, the more I have come to realize that life is not so simple. We frequently have patients with strep and mononucleosis, or strep and influenza; so, maybe you have a "double diagnosis" as well. Please schedule a follow-up visit with your doctor. Some strep infxns express copathogenicity. ...Read more

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Can Amoxcillin make u tired if it's 875mg tablet? Can Amoxcillin help clear stuffy nose if it's due to sinusitis?

Can Amoxcillin make u tired if it's 875mg tablet? Can Amoxcillin help clear stuffy nose if it's due to sinusitis?

Maybe but...: Amoxicillin is a very good antibiotic, but it is not indicated for all infections. I would get to a Dr. Who can possibly do a swab and help determine what meds may be best for your issues. ...Read more

Dr. Philip Miller
1,141 Doctors shared insights

Amoxil (Definition)

Amoxil is a third generation penicillin which is a kind of penincillin type drug (anti-bacterial ...Read more