Doctor insights on:
Can Alcoholism Cause You To Have Pernicious Anemia
No: Unaware of any association. True pernicious anemia is an autoimmune disease, caused by antibodies to the cells in our stomachs that produce intrinsic factor, which is needed to absorb vitamin B12 from our intestines. It may be hereditary or acquired. There are other causes of B12 deficiency, including stomach and intestinal diseases/surgery, and lack of B12 in diet. A hematologist can help. ...Read more
Low vitamin B12: Pernicious anemia is a condition in which the body is unable to absorb vitamin B12 through the stomach due to loss of a protein called intrinsic factor in the stomach. Treatment invovles replacing b!2 through injections or nasal sprays- taking oral pills is ineffective. ...Read more
No intrinsic factor: B12 in the diet usually binds to intrinsic factor in the stomach and then gets absorbed by the small bowel. In pernicious anemia, there is low or no intrinsic factor being made by the stomach cells. As a result, there is gradual deficit of B12 stores and eventaully as all the B12 is gone the new red blood cell production is affected. ...Read more
B12=262 & muscles have gotten weak in the past month. Grandmother and great-grandmother both had pernicious anemia and/or B12 def. Cause for concern?
Yes: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your B12 level is just at the lower limit of normal. Your family history does put you at risk for B12 deficiency. It can be corrected with B12 injections at one to 3 month intervals. It would be prudent to consult your doctor. ...Read more
Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more
Low vitamin B12.: Pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. ...Read more
Yes: B12 deficiency can cause severe brain issues such as what you are describing. ...Read more
Yes! To both!!: Both may be autoimmune diseases and frequently are hereditary! Both are very easily diagnosed by lab tests! See your physician if you think you have either of these illnesses! ...Read more
Hematocrit normal but got high MCV. Could having pernicious anemia be the cause of my long term panic disorder? B12 produces neurotrans.through methylat
A b12 level will confirm that the amount in your system is more than adequate.
B12 is in all animal products and is stored for months. Deficiencies occur:
in the elderly with very thin absorption areas in the gut that can't get it in.
rare parasitic diseases
total hardcore Vegans ...Read more
Autoimmune disease: Pernicious anemia is an autoimmune disease producing autoantibodies against intrinsic factor found in the lining of the stomach. This leads to lack of absorption of vitamin B12 which is important in making blood cells and for nourishment of the nervous system. Treatment would be by replacement of B12 via injections or absorption into the body by other means (nasal spray). ...Read more
The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read more
Can 7yrs of undiagnosed coeliacs cause pernicious anemia, irreversible villi damage and miscarriages?
Gi issues: This is a question best answered by a gastro intestinal specialist, I would seek a consult to find this answer. ...Read more
Pernicious anemia...: Is due to B12 def arising from loss of intrinsic factor production by parietal cells in the stomach and required for B12 absorption in the gut. Anything that produces B12 def can cause these symptoms. Classically, pa is one such diagnosis that is due to destruction of parietal cells by the immune system (ie., an autoimmune disorder). I suspect elevated igg is true, true and unrelated. See your dr. ...Read more
Had low B12 which is now normal no explained reason for it- not on any medication, no operations, no pernicious anemia, nothing at al. What caused it?
B12: Actually takes a long time to become B12 deficient. If you are a vegetarian this may occur, otherwise may have been an inaccurate test result. ...Read more
The two are linked:
This finding goes back to 1964, believe it or not:
http://www.Ncbi. Nlm. Nih. Gov/pmc/articles/pmc1552204/? Page=1
There are autoimmune antibodies in both conditions, so while one might not cause the other, the two are related. ...Read more
What would cause low ferritin (13 last yr, now 9) if RBC indices are normal & so is iron panel? Thyroid ok. I take IM B12 for pernicious anemia. 28f
Early deficiency: Serum ferritin drops off before anemia appears or red cell indices go abnormal. Your physician will ask you about diet, your cycle, and whether you're perhaps having blood loss via the gut -- he / she will check. If you are a non-supplementing vegetarian, please reconsider. Best wishes. ...Read more
Can pernicious anemia cause you to lose all sensitivity in the vagina area loosing your ability to feel any sexual pleasure, arousal or reach an orgasm
Penicious anemia: Pernicious anemia can be presented with numbness and tingling, memory problem, loss of cocnentration, fatigue etc. I do not know however if it will give you only problem with loss of sensation to the genitalia area only. I doubt that it is caused by pernicious anemia mainly. Your problem is more complicated than just pernicious anemia in my opinion-it involves both physical and emotional aspects. ...Read more
Does one's CBC count have to be in an anemic range in order to have pernicious anemia? W/o B12 shots hubby's B12 is very low. W/ shots in 300's
Cobalamin therapy: Try a trial of vitamin B12 (cobalamin) first and have a physician to repeat lab to ensure adequate dose. Also, it may need additional therapies for cobalamin deficiency due to underlying diseases involving intestine or pancreas. Please check for Folic Acid deficiency as well and this may be related to nutritional deficiency. If you are a vegetarian, please take vitamin B12 daily. ...Read more
Due 2 B12 deficiency: It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily treatable with replacement therapy. ...Read more
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