Doctor insights on:
Can Agent Orange Cause Diffuse Large B Cell Lymphoma
No one knows: Certainly some other cancers have been linked but as far as i know there is no direct linkage. On the other hand, herbicides have had an association with lymphoma and myeloma and agent orange is a "super herbicide". It is always hard to show a direct linkage. ...Read moreSee 1 more doctor answer
What is the association between lymphoma and hypothyroidism? Can agent orange cause hypothyroidism?
Lymphoma and thyroid: Hashimoto's thyroiditis is an immune attack on the thyroid which can over time provoke lymphoma through overstimulation of the lymph tissue in the area. Lymphoma can also be seen with other autoimmune conditions such as sjogren's syndrome, crohn's disease, common variable immunodeficiency, and rheumatoid arthritis. I couldn't find any medical reports linking agent orange and hypothyroidism. ...Read more
No: We can only guess what causes diffuse large b-cell lymphoma, but we know there are at least 3 genetic subtypes. See: http://www.bloodjournal.org/content/105/5/1851 This implies gene mutations are very important in this disease, as in most (if not all) blood borne malignancies. As far as anyone knows, Aleve PM (or any drug like it ) does not cause genetic mutation or clearly increase cancer risk. ...Read moreSee 1 more doctor answer
Yes: Agent orange is phenoxyl hercides chemically. Epidemiology study showed an association between such as exposure and non-hodgkin's lymphoma including folicular lymphoma. An interesting article publised in J Exp Med noted a drastic clonal expansion of t(14:18) B cells in patient's blood exposed to various pesticides. Chromosomal translocation (14:18) is a hallmark for follicular lymphoma. ...Read more
Fairly quickly: This is a very fast growing disease which in most cases has already caused some damage before it is discovered. It is important to quickly stage the disease and then begin treatment. Your oncologist will know how much time can pass before you start treatment. Everyone is different in this respect and sometimes life's issues (graduations, weddings) can be worked around..And sometimes not. ...Read moreSee 1 more doctor answer
My grand father (79 years) has been diagnosised with diffuse large "b" cell lymphoma, high grade. Please tell me this is which stage.Thnks.
More information?: Stage depends on location for non-hodgkin's lymphoma. How many lymph node groups were involved, where exactly they were located. Your doctor should be able to tell you the stage. ...Read more
What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?
It depends.: R-cvp is a relatively milder regimen and therefore it does not usually result in very low wbcs. In general, modest decrease in WBC is expected and is not associated with higher risk for infections unless WBC become very low with neutrophil count below 500. If this is the case, you doctor may decide to use a growth factor given after chemotherapy to stimulate your bone marrow to produced wbcs. ...Read more
Maybe: In general we don't think of diffuse large b cell lymphoma (dlbcl) effecting brain function. However, many patients tell us of symptoms of a "fog" like feeling either before treatment (disease-related?) or after ("chemobrain"). Reasons are likely multifactorial and can include stress, financial concerns, depression, and disease biology. This is being actively studied by a variety of groups. ...Read moreSee 1 more doctor answer
- Talk to a doctor live online for free
- How quickly should treatment start for diffuse large b cell lymphoma?
- Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?
- Non hodgkins diffuse large b cell lymphoma
- Ask a doctor a question free online
- Difuse large b cell lymphoma
- Primary mediastinal large b cell lymphoma
- Diffuse large cell lymphoma symptoms
- What is large b cell lymphoma?
- Talk to a infectious disease specialist online