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Doctor insights on: Can Agent Orange Cause Diffuse Large B Cell Lymphoma

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Can agent orange cause diffuse large b cell lymphoma?

Can agent orange cause diffuse large b cell lymphoma?

No one knows: Certainly some other cancers have been linked but as far as i know there is no direct linkage. On the other hand, herbicides have had an association with lymphoma and myeloma and agent orange is a "super herbicide". It is always hard to show a direct linkage. ...Read more

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Dr. Michael Thompson
1,746 doctors shared insights

Lymphoma (Definition)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then ...Read more


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What is the association between lymphoma and hypothyroidism? Can agent orange cause hypothyroidism?

What is the association between lymphoma and hypothyroidism? Can agent orange cause hypothyroidism?

Lymphoma and thyroid: Hashimoto's thyroiditis is an immune attack on the thyroid which can over time provoke lymphoma through overstimulation of the lymph tissue in the area. Lymphoma can also be seen with other autoimmune conditions such as sjogren's syndrome, crohn's disease, common variable immunodeficiency, and rheumatoid arthritis. I couldn't find any medical reports linking agent orange and hypothyroidism. ...Read more

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Can aleve (naproxen) pm cause diffuse large b-cell lymphoma?

Can aleve (naproxen) pm cause diffuse large b-cell lymphoma?

No: We can only guess what causes diffuse large b-cell lymphoma, but we know there are at least 3 genetic subtypes. See: http://www.bloodjournal.org/content/105/5/1851 This implies gene mutations are very important in this disease, as in most (if not all) blood borne malignancies. As far as anyone knows, Aleve (naproxen) PM (or any drug like it ) does not cause genetic mutation or clearly increase cancer risk. ...Read more

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Are follicular lymphoma and Agent Orange related at all?

Are follicular lymphoma and Agent Orange related at all?

Non-Hodgkin lymphoma: is considered a presumptive disease for Agent Orange by the Department of Veteran's Affairs. ...Read more

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Dr. Le Wang Dr. Wang
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Are there any studies linking follicular lymphoma and Agent Orange?

Dr. Le Wang Dr. Wang
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Are there any studies linking follicular lymphoma and Agent Orange?

Yes: Agent orange is phenoxyl hercides chemically. Epidemiology study showed an association between such as exposure and non-hodgkin's lymphoma including folicular lymphoma. An interesting article publised in J Exp Med noted a drastic clonal expansion of t(14:18) B cells in patient's blood exposed to various pesticides. Chromosomal translocation (14:18) is a hallmark for follicular lymphoma. ...Read more

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How quickly should treatment start for diffuse large b cell lymphoma?

How quickly should treatment start for diffuse large b cell lymphoma?

Fairly quickly: This is a very fast growing disease which in most cases has already caused some damage before it is discovered. It is important to quickly stage the disease and then begin treatment. Your oncologist will know how much time can pass before you start treatment. Everyone is different in this respect and sometimes life's issues (graduations, weddings) can be worked around..And sometimes not. ...Read more

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My grand father (79 years) has been diagnosised with diffuse large "b" cell lymphoma, high grade. Please tell me this is which stage.Thnks.

My grand father (79 years) has been diagnosised with diffuse large "b" cell lymphoma, high grade. Please tell me this is which stage.Thnks.

More information?: Stage depends on location for non-hodgkin's lymphoma. How many lymph node groups were involved, where exactly they were located. Your doctor should be able to tell you the stage. ...Read more

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Treatment options for diffuse large b-cell lymphoma?

Treatment options for diffuse large b-cell lymphoma?

R-CHOP: The most common regimen is r-chop (rituximab, cytoxan, adriamycin, (doxorubicin) vincristine, prednisone). Other options are epoch-r, a clinical trial. There are several regimens, but the most common regimen is r-chop. It also varies on the stage of the disease. Hope this helps. ...Read more

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What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?

What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?

It depends.: R-cvp is a relatively milder regimen and therefore it does not usually result in very low wbcs. In general, modest decrease in WBC is expected and is not associated with higher risk for infections unless WBC become very low with neutrophil count below 500. If this is the case, you doctor may decide to use a growth factor given after chemotherapy to stimulate your bone marrow to produced wbcs. ...Read more

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Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?

Maybe: In general we don't think of diffuse large b cell lymphoma (dlbcl) effecting brain function. However, many patients tell us of symptoms of a "fog" like feeling either before treatment (disease-related?) or after ("chemobrain"). Reasons are likely multifactorial and can include stress, financial concerns, depression, and disease biology. This is being actively studied by a variety of groups. ...Read more

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What is the survival rate with large b cell lymphoma stage 4?

What is the survival rate with  large b cell lymphoma stage 4?

50%: However, there are numerous features about an individual lymphoma that point to worse or better survival for that individual. And survival is dependent on treatment as well; the use of the monoclonal antibody, rituximab, greatly impacts on survival. Finally, the medical community does not equate survival with cure, so we tend to talk about five year survival and ten year survival. ...Read more

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How quick should treatment start for large b cell lymphoma?

How quick should treatment start for large b cell lymphoma?

As soon as possuble: This is usually a very cellular and rapidly expanding neoplasm. Treatment can ususlly result in rapid response but the patient must be monitored closely for development of tumor lysis syndrome. ...Read more

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Can I finsd information on large b cell lymphoma?

Try nci.nih.giv: The natinal cancer institute web site can provide avgreat desl of information fir both patients and professionals. ...Read more

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Is diffused b cell lymphoma genetic?

Not really: While there may be a genetic suscepibiltiy to developing lymphoma it is not truly a genetic disease. ...Read more

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What is diffused b cell lymphoma?

Aggressive lymphoma: This is a type which is usually aggressive and can present at an advanced stage. Fortunately, the majority do respond well to modern chemotherapy regimens. A significant number relapse and require more therapy/ transplant. ...Read more

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What is badly diffused b cell lymphoma?

Not a common term: Diffuse b cell lymphoma is by definition an aggressive lymphoma which has the ability to spread rapidly if not treated. It is a "bad actor". I assume this term may be referring to a lymphoma that has already spread a good deal before being diagnosed. Even so, these lymphomas are often treatable and can be cured in the majority of cases. ...Read more

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What is the rate of survival of a diffuse b-cell lymphoma?

It is quite good: These are fast growing lymphomas that respond well to modern chemotherapy. Your doctor can tell you what risk category you fall into based on your age and several aspects of your tumor which include it's stage at presentation. Outside of this, staying on time with chemotherapy and not having to reduce the intended dose lead to the highest cure rates. The majority of patients can be cured. ...Read more

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Can Agent Orange cause Huntington's Disease?

NO: Agent Orange has been implicated in many disorders, but Huntington's is an autosomal dominant hereditary disorder, and NEVER secondary to chemical exposure. ...Read more

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If exposed to agent orange and other toxic chemicals. later.in life cause muscular dystropy?

If exposed to agent orange and other toxic chemicals. later.in life cause muscular dystropy?

Probably not but...: Agent Orange contains dioxin, a toxic chemical proven to cause many serious illnesses. Muscular dystrophy is something people are born with. Agent Orange may cause Muscular dystrophy in the children of those exposed to it but isn't known to cause it directly in those exposed. See http://www.veteranshealth.org/Vietnam/AO.html A holistic/integrative physician can evaluate/treat illness from toxins. ...Read more

Dr. Al Hegab
47 doctors shared insights

Agent Orange (Definition)

Agent Orange is the name for a chemical used during the Vietnam war to kill plants but that also killed people ...Read more