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Doctor insights on: Can Agent Orange Cause Diffuse Large B Cell Lymphoma

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Can agent orange cause diffuse large b cell lymphoma?

Can agent orange cause diffuse large b cell lymphoma?

No one knows: Certainly some other cancers have been linked but as far as i know there is no direct linkage. On the other hand, herbicides have had an association with lymphoma and myeloma and agent orange is a "super herbicide". It is always hard to show a direct linkage. ...Read more

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Dr. Michael Thompson
1,724 doctors shared insights

Lymphoma (Definition)

Lymphoma is cancer of the lymph system, which is an infection fighting collection of nodes of lymph tissue populated by white blood cells and ducts that drain excess fluid. The system ...Read more


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What is the association between lymphoma and hypothyroidism? Can agent orange cause hypothyroidism?

What is the association between lymphoma and hypothyroidism? Can agent orange cause hypothyroidism?

Lymphoma and thyroid: Hashimoto's thyroiditis is an immune attack on the thyroid which can over time provoke lymphoma through overstimulation of the lymph tissue in the area. Lymphoma can also be seen with other autoimmune conditions such as sjogren's syndrome, crohn's disease, common variable immunodeficiency, and rheumatoid arthritis. I couldn't find any medical reports linking agent orange and hypothyroidism. ...Read more

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Can aleve (naproxen) pm cause diffuse large b-cell lymphoma?

Can aleve (naproxen) pm cause diffuse large b-cell lymphoma?

No: We can only guess what causes diffuse large b-cell lymphoma, but we know there are at least 3 genetic subtypes. See: http://www.bloodjournal.org/content/105/5/1851 This implies gene mutations are very important in this disease, as in most (if not all) blood borne malignancies. As far as anyone knows, Aleve (naproxen) PM (or any drug like it ) does not cause genetic mutation or clearly increase cancer risk. ...Read more

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Are follicular lymphoma and Agent Orange related at all?

Are follicular lymphoma and Agent Orange related at all?

Non-Hodgkin lymphoma: is considered a presumptive disease for Agent Orange by the Department of Veteran's Affairs. ...Read more

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Dr. Le Wang Dr. Wang
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Are there any studies linking follicular lymphoma and Agent Orange?

Dr. Le Wang Dr. Wang
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Are there any studies linking follicular lymphoma and Agent Orange?

Yes: Agent orange is phenoxyl hercides chemically. Epidemiology study showed an association between such as exposure and non-hodgkin's lymphoma including folicular lymphoma. An interesting article publised in J Exp Med noted a drastic clonal expansion of t(14:18) B cells in patient's blood exposed to various pesticides. Chromosomal translocation (14:18) is a hallmark for follicular lymphoma. ...Read more

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How quickly should treatment start for diffuse large b cell lymphoma?

How quickly should treatment start for diffuse large b cell lymphoma?

Fairly quickly: This is a very fast growing disease which in most cases has already caused some damage before it is discovered. It is important to quickly stage the disease and then begin treatment. Your oncologist will know how much time can pass before you start treatment. Everyone is different in this respect and sometimes life's issues (graduations, weddings) can be worked around..And sometimes not. ...Read more

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My grand father (79 years) has been diagnosised with diffuse large "b" cell lymphoma, high grade. Please tell me this is which stage.Thnks.

My grand father (79 years) has been diagnosised with diffuse large "b" cell lymphoma, high grade. Please tell me this is which stage.Thnks.

More information?: Stage depends on location for non-hodgkin's lymphoma. How many lymph node groups were involved, where exactly they were located. Your doctor should be able to tell you the stage. ...Read more

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Treatment options for diffuse large b-cell lymphoma?

Treatment options for diffuse large b-cell lymphoma?

R-CHOP: The most common regimen is r-chop (rituximab, cytoxan, adriamycin, (doxorubicin) vincristine, prednisone). Other options are epoch-r, a clinical trial. There are several regimens, but the most common regimen is r-chop. It also varies on the stage of the disease. Hope this helps. ...Read more

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What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?

What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?

It depends.: R-cvp is a relatively milder regimen and therefore it does not usually result in very low wbcs. In general, modest decrease in WBC is expected and is not associated with higher risk for infections unless WBC become very low with neutrophil count below 500. If this is the case, you doctor may decide to use a growth factor given after chemotherapy to stimulate your bone marrow to produced wbcs. ...Read more

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Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?

Maybe: In general we don't think of diffuse large b cell lymphoma (dlbcl) effecting brain function. However, many patients tell us of symptoms of a "fog" like feeling either before treatment (disease-related?) or after ("chemobrain"). Reasons are likely multifactorial and can include stress, financial concerns, depression, and disease biology. This is being actively studied by a variety of groups. ...Read more

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Dr. Neigatha Graney
47 doctors shared insights

Agent Orange (Definition)

Agent Orange is the name for a chemical used during the Vietnam war to kill plants but that also killed people ...Read more