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Doctor insights on: Can A Solid Hypoechoic Nodule In Thyroid Gland Be Cancer

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Dr. Barry Rosen
4,344 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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I had a ct scan of neck, they saw small hypoechoic nodule in thyroid and an enlarged lymphnode, is it cancer?

Thyroid nodules: This is a very common finding, and the fact that it is small suggests lower risk. Usually under 1 cm they don't bother to biopsy, but perhaps with an enlarged LN in the area it might need it. Fine Needle aspiration biopsy can be safely and easily done perhaps with US guidance and a pathologist to evaluate the sample to ensure it is sufficient and triaged to the appropriate next steps. Most r b-9 ...Read more

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Decrease in thyroid gland size and increase in thyroid nodule size?

Decrease in thyroid gland size and increase in thyroid nodule size?

Concern: Thyroid gland do not change in size that much. Majority of thyroid nodules are benign, increase in size is a concern, should have fna biopsy (cytology) to make sure there is no malignancy in it. ...Read more

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Male with dominant homogenous solid thyroid nodule in midpoint that measures 1.1x1.3x1.7. Does this indicate a high cancer risk? Are most benign?

Most are benign: Hi. Yes, most nodules with those characteristics are benign. I'll assume you're not hyperthyroid (hyper-functioning nodules are NEVER cancer). Nevertheless, the chance of cancer is high enough (about 10-15% for nodules like that) that you MUST get it biopsied (non-surgical needle biopsy with gene testing is recommended). Don't ignore it, and don't ASSUME benignity. Cheers! ...Read more

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Does a homogeneous or heterogeneous solid thyroid nodule have more cancer risk? I see lots of info on heterogeneous but not on homogeneous.

Does a homogeneous or heterogeneous solid thyroid nodule have more cancer risk? I see lots of info on heterogeneous but not on homogeneous.

Depend solid or cyst: Thyroid nodule either solis or cystic and that could be done by ultrasound next it has to be classified as cold or hot or warm and that could be done by thyroid scan if it is solid and cold have higher tendency to be malignant oat of thyroid nodules are benign if it is of some concern the doctor will perform fine needle aspiration to exclude malignancy you should be under doctor carei ...Read more

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Male with dominate homogenous solid thyroid nodule measuring 1.1x1:3x1.7. US says somewhat hyper-vascular. Are the cancer risk high? Need a FNB?

Male with dominate homogenous solid thyroid nodule measuring 1.1x1:3x1.7. US says somewhat hyper-vascular. Are the cancer risk high? Need a FNB?

Could be cancer: Hi. A nodule with those characteristics could be a cancer, although the odds are in your favor that it's not based on years of data on thyroid nodules. You need an FNA, and I recommend doing it with gene testing (such as the Afirma thyroid FNA system; your endocrinologist will be aware of this, and probably uses it). The gene testing reduces surgery for non-diagnostic cytology. ...Read more

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1 year thyroid nodule follow-up revealed a new thyroid nodule and the other one is no longer there. They were both hypoechoic. Chance this is cancer?

1 year thyroid nodule follow-up revealed a new thyroid nodule and the other one is no longer there. They were both hypoechoic. Chance this is cancer?

It is usually benign: The risk for a thyroid nodule to be cancerous actually is only 5-6%- and majority of thyroid nodule is benign.
Having said that, the risk of developing thyroid cancer will be higher if you have significant risk like previous exposure to radiation to the neck area at early age (childhood), family history of thyroid cancer etc.
You need to continue to f/u with your doctor and sono as indicated. ...Read more

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.6mx.5mmx.3.4mm cystic thyroid nodule which is hypoechoic. Cancer risk? Grow. 2mm since 1, 5 years. Really worrying that's hypoechoic please explain

.6mx.5mmx.3.4mm cystic thyroid nodule which is hypoechoic. Cancer risk? Grow. 2mm since 1, 5 years. Really worrying that's hypoechoic please explain

Likely benign: Cystic hypoechoic nodule is usually benign particularly without solid components. However some malignant tumors have cystic components. 0.2mm growth in 11/2 years is slow growth. Most malignant tumors grow faster. Most nodules less than 1 cm are not biopsied. Most small nodules are usually benign. You are correct in getting follow up US exams. Hyperechoic lesions are denser sometimes with calcium. ...Read more

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I have a 4.5 x 3.5 thyroid nodule: solid, hypervascular. My tgab is at 70 and TSH is 3.15. I am symptomatic. Is this a cancer marker?

I have a 4.5 x 3.5 thyroid nodule: solid, hypervascular. My tgab is at 70 and TSH is 3.15. I am symptomatic. Is this a cancer marker?

No: Tgab and TSH are not cancer markers. It's important to know if the nodule is 4.5 cm or mm? If cm, you should get an ultrasound guided biopsy. If mm, it is very small and just need surveillance. If you are young and already symptomatic with a 4.5 cm thyroid mass, surgery is an option for you. Please discuss all this with your doc. ...Read more

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I have a 4.4cmx3.5cmx1.1cm solid thyroid nodule. The report read "Microcalcifications" and "Hypervascular". What is the likelihood that it is cancer?

I have a 4.4cmx3.5cmx1.1cm solid thyroid nodule. The report read "Microcalcifications" and "Hypervascular". What is the likelihood that it is cancer?

Needs Biopsy: Thyroid nodule with microcalcification&hypervascularity have a likelihood of being Cancerous in about approx 5.3 % of cases according to literature. Ask your endocrinologist for Biopsy
We really need other teatures like irregular or regular border, Pattern of calcifications like few few or snowstorm parttern, minimal or high internal flow
These are other features taken into account to prediction ...Read more

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My ultrasound showed cervical lymphadenopathy and hetergeneous ill-defined solid thyroid nodule. Could this be cancer?

Needs med Evaluation: You should go see your doctor and get further investigations. The thyroid nodule may need a biopsy which is best arranged after visiting an endocrinologist or thyroid specialist (ent doctor). ...Read more

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M w/ hypothyroidism (2 yrs). US identified dominant homogeneous solid thyroid nodule >1 CM. No mention of hyper or hypoechoic. Are cancer risk high?

M w/ hypothyroidism (2 yrs). US identified dominant homogeneous solid thyroid nodule >1 CM. No mention of hyper or hypoechoic. Are cancer risk high?

Not necessarily: Incidence of malignancy is 4% when a solid thyroid nodule is hyperechoic. If the lesion is hypoechoic, the incidence of malignancy rises to 26% although using this as criteria to determine likelihood of malignancy isn't very accurate. In general, thyroid cancer is an uncommon malignancy which constitutes about 0.5% of all malignancies. Follow up with your doctor is recommended for additional tests ...Read more

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Is it poss. Cancer? Us results thyroid nodule: solid, heterogeneous & isoechoic nodule w/in the mid to lower right lobe, 4.2cm, increas. Vascularity

Yes it's possible: Any thyroid nodule over 4 cm needs to be removed surgically to make sure not cancerous per ata guidelines. I would still get a fna first before going to surgery but needs to be removed. More info on my website on thyroid nodules at www. Cvsurgicalgroup. Com. ...Read more

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3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

Not necessarily...: The fact that FNA was reported as benign, the nodule is unlikely to be malignant. Small droplets of benign colloid often mimic "microcalcificatins" of papillary tumor, hence caution is advised. I would suggest repeating the FNA, and consider also collecting samples for gene profiling studies, such as, those manufactured by Veracyte and Asuragen (Note:I have no financial/other interest.) ...Read more

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Solid heterogeneous thyroid nodule 15mm to 3cm in 2 years and normal TSH levels. If it is cancer, could it have spread over the 2 years? Fna tomorrow.

Solid heterogeneous thyroid nodule 15mm to 3cm in 2 years and normal TSH levels. If it is cancer, could it have spread over the 2 years? Fna tomorrow.

Unlikely: Thyroid nodules are a fairly common finding. In the setting of a normal tsh, an fna is the appropriate next step. The good news is the very large majority are benign. An fna is the only way to know for sure though. Best of luck! ...Read more

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Single hypoechoic solid thyroid nodule over 1cm with mild vascularity?

Hyperplastic nodule: This sounds like a hyper plastic nodule. These are usually benign. In the absence of prior studies, this usually is followed up to show it's stable nature. If it changes or grows it would need a biopsy. Nonetheless would suggest an in depth discussion with your doctor ...Read more

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Right side upper pole solid hypoechoic single thyroid nodule mean? Worried..

Depends: It all depends on the size and if it is new. There is a need to do needle aspiration if not sure ...Read more

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12mm slightly complex THYROID nodule (R) + 10x6x5mm hypoechoic nodule (R). Impression: largest predominantly solid appearing nodule is 10mm. GET FNA?

12mm slightly complex THYROID nodule (R) + 10x6x5mm hypoechoic nodule (R). Impression: largest predominantly solid appearing nodule is 10mm. GET FNA?

FNA: The 12 mm nodule and the 10 mm nodule should both get an FNA. I'd advise doing the FNAs with thyroid cancer gene panel testing. Most are benign, so please don't be concerned until and unless you get bad results from the FNAs. Good luck! ...Read more

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What does a small non reactive left submandibular lymph node and a right side upper pole solid hypoechoic single thyroid nodule mean? Worried..

Benign: Small reactive node means just that, ...... no worries just follow up

Solitary solid nodule can be benign... rec thyroid I uptake scan if hot benign if cold on uptake scan consider biopsy
...Read more

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1st FNA is benign follicular lesion, u/s ;hypoechoic thyroid nodule with few small calcifications, 2nd FNA ; hard consistency solid nodule, %ofcancer?

1st FNA is benign follicular lesion, u/s ;hypoechoic thyroid nodule with few small calcifications, 2nd FNA ; hard consistency solid nodule, %ofcancer?

Talk to YOUR MD: You clearly have a thyroid problem, and this needs to be discussed in context of the bigger clinical picture. If you have had FNA done, you have a doc following you. See them and ask what this means in your case and what should be done next. Lab results never occur in isolation. They occur in people, and the whole person has to be considered when making a diagnosis and treatment plan. Best wishes! ...Read more

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A 0.3 x 0.5 x 0.3 CM hypoechoic cystic nodule with punctate internal echo is noted in the lower pole of the right lobe of the thyroid gland.?

Small nodule: Often cystic thyroid nodules can have denser regions called "punctate foci". If the nodule is not cystic those can also be microcalcifications, a finding that increases the risk of thyroid cancer. The key though is that the nodule is very small and therefore requires monitoring only, no matter what its nature may be. ...Read more

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Thyroid gland appears borderline small in size. Small 3x2x3 mm hypoechoic nodule of mid right thyroid lobe with some mild associated vascularity?

Common: Thyroid nodules are common. Your nodule is still very small. Nothing needs to be done right now. I recommend another ultrasound one year from now to monitor for size changes. ...Read more

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Heterogeneous appearance thyroid gland with complex solid & cystic nodule posterior margin upper pole right lobe 1.5x1.4x1.0cm, what does this mean?

Heterogeneous appearance thyroid gland with complex solid & cystic nodule posterior margin upper pole right lobe 1.5x1.4x1.0cm, what does this mean?

Possible biopsy: Many people have thyroid issues and have ultrasounds that can show a multitude of issues. Most findings are benign and typically are cysts. Biopsies are done routinely for solid nodules to make sure they are benign or not. You may require some thyroid replacement but thyroid blood tests are also required. She your primary or an endocrinologist since they specialize in thyroid issues. Good luck ...Read more

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Thyroid U/S showed L thyroid gland heterogeneous hypoechoic nodule w/ mind internal vascularity. What does all this mean? FNA recommended.

Means abnormal test: Ultrasound is a commonly used test for detection of Throid nodules which are quite common. So when the ultrasound shows a Thyroid nodule, it needs to be monitored and often a Biopsy is required to find out if the nodule is benign or cancerous. FNA is one such technique for obtaining a biopsy for making a diagnosis. ...Read more

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Thyroid nodule at 3.4 x 4.7 x 2.3cm. Blood tests confirm all is normal. Ultrasound shows heterogeneous iso/small area hypechoic. Chances of cancer?

Thyroid nodule at 3.4 x 4.7 x 2.3cm. Blood tests confirm all is normal. Ultrasound shows heterogeneous iso/small area hypechoic. Chances of cancer?

Yes, some: You need to see an endocrinologist. Who would likely do a fine needle aspiration (fna) biopsy. Thyroid cancer needs to be ruled out by further testing. It has to be a consideration in your case. But thyroid cancer is easily treatable and highly curable (>95%). ...Read more

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I had a sonogram of my thyroid. I have 9 nodules/cyst. 2 solid hypoechoic heterogeneous nodules. What does this mean? Cancer?

Common problem: Nodules of the thyroid are common, especially in women. Most thyroid nodules are benign. "solid", "hypoechoic", "heterogeneous" nodules are the most common ones seen. If they are large enough (at least 1 cm), we typically recommend doing a fine needle biopsy to make sure they are benign. ...Read more

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Unable to determine from a needle asp. If I have cancer in thyroid nodule. What's next step?

Unable to determine from a needle asp. If I have cancer in thyroid nodule. What's next step?

Options: You could rebiopsy. Maybe this time, also send out one tube for gene expression (molecular cytopath) to aid in the diagnosis. You could also go for surgery with biopsy taken while under anesthesia (frozen section) and proceed with total thyroidectomy if the intraoperative biopsy showed cancer. You could follow closely with ultrasound and rebiopsy if changes are seen with the nodule... ...Read more

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I'm 28 years old, had a thyroid nodule for 2 years. Finally got a biopsy. How likely is it to be cancer?

I'm 28 years old, had a thyroid nodule for 2 years. Finally got a biopsy. How likely is it to be cancer?

Likelihood: Depends on size, whether it is solid, cystic, or complex, whether or not it is a "cold" nodule, and a lot of other things. Even if it is thyroid cancer, most of these are successfully treated with surgery with or without radiotherapy. ...Read more

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Could FNB on 2.3cm Thyroid Nodule cause problem if it IS cancer? Like breaking the seal & spreading cancer faster. Deciding on FNB or Lobe removal?

Could FNB on 2.3cm Thyroid Nodule cause problem if it IS cancer? Like breaking the seal & spreading cancer faster. Deciding on FNB or Lobe removal?

FNB is safe: FNB is commonly done on thyroid nodules and lumps in the breast. It is the first step to make a diagnosis of Cancer. it is better to do FNB than surgery to remove a lump the surgeon needs to know ahead of time what he/she is removing? FNB next is the way to go in your case. ...Read more

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What to do if I have a calcified thyroid nodule. Can it be thyroid cancer?

USG FNA: At first, most probably you should have ultrasound guided fine needle aspiration after consultation with your physician.
Calcifications can be seen in benign nodular goiter.
So, continue evaluation of your thyroid nodule, to rule out thyroid cancer, follow all tests what your physician ask you to do.
Thanks for question. Stay well. ...Read more

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Might a benign thyroid nodule someday become a cancer?

Might a benign thyroid nodule someday become a cancer?

Not 100%: If the nodule is still in your neck, there is no way to know that it is 100% benign. Even if you had a biopsy before and it came back benign, there is still a chance that the spot of cancer was missed during the first biopsy. This is why we don't "poo poo" it away after 1 biopsy but continue to follow the thyroid nodule to monitor for size changes. All said, the risk of cancer is very small. ...Read more

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How can a thyroid nodule grow in a gland bed of post total thyroidectomy?

How can a thyroid nodule grow in a gland bed of post total thyroidectomy?

Radioactive iodine?: Did you ever have a radioactive iodine ablation to get rid of remnant tissue? Residual tissue in the thyroid bed could be remnant tissue or recurrence. ...Read more

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Is my complex thyroid nodule taller than wide? It's 12 mm x 6 mm x 5 mm? Does this mean cancer?

Is my complex thyroid nodule taller than wide? It's 12 mm x 6 mm x 5 mm? Does this mean cancer?

In order: To determine whether the nodule is taller than wide, you need to specify the orientation of those measurements: Anterior-posterior (AP), transverese (T), and longitudinal. If the AP/T ratio is greater than 1, the nodule is taller than wide. An A/P >1 does not necessarily mean cancer, but along with other features, may indicate the need for FNA biopsy. ...Read more

Thyroid Gland (Definition)

It is an endocrine gland which produces thyroxin hormone which controls the metabolism in every cell in the body. It produces 80 to 90%t4 and 10 to 20 %t3. These control rate of metabolism and affect the growth and rate of functions of many cells in the body it is ...Read more


Nodule (Definition)

Any growth or deposit in the body or on its surface may be casually termed a nodule until its character is determined by the familiarity of the physician with it or by the results of a biopsy if it is not so obvious. The term is casual ...Read more