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Doctor insights on: Can A Lack Of Calcium Lead To Osteogenesis Imperfecta

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Dr. Neigatha Graney
99 doctors shared insights

Osteogenesis Imperfecta (Definition)

A condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more


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What can lead to the blue sclera in osteogenesis imperfecta?

What can lead to the blue sclera in osteogenesis imperfecta?

It doesn't: Where the sclera is thin, it appears blue from the deoxygenated blood the choroidal blood vessel layter next tot he sclera. This is normal in patients who are nearsighted. Rarely, this is a sign associated with osteogenesis imperfecta. Not a cause. Not diagnostic. ...Read more

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Can a deficiency in a certain vitamin lead to heart disease ?

Can a deficiency in a certain vitamin lead to heart disease ?

Yes: In the last few years, studies have revealed that vitamin d3 deficiency is associated with increased risk of cardiac events. At the same time, vitamin d3 deficiency is quite common, especially in our northern climate where exposure to the sun, which is required for our bodies to produce this vitamin, is limited to the summer months. If your level is low, oral supplements can remedy this problem. ...Read more

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Can anemia lead to a lack of concentration?

Can anemia lead to a lack of concentration?

Yes: Symptoms common to many types of anemia (low hemoglobin) include the following: easy fatigue and loss of energy, rapid heart beat (particularly with exercise), shortness of breath, headache, difficulty concentrating, dizziness, pale skin, leg cramps, and insomnia. ...Read more

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Can signs of joint deterioration show up after a week of a severe lack of certain nutrients? Ie: calcium or vitamin d?

Can signs of joint deterioration show up after a week of a severe lack of certain nutrients? Ie: calcium or vitamin d?

Joint degeneration: Typically joint degeneration is from chronic wear and tear or acute trauma. Nutrient deficiency would take years to affect joints. ...Read more

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Which type of vitamin and mineral deficiencies lead to depression?

Which type of vitamin and mineral deficiencies lead to depression?

B, D and omega 3: There are a few vitamin deficiencies that have been linked to depression : b vitamins and vitamin d. Supplements such as omega 3 fatty acids may also play a role in depression. Omega 3 can be used as a treatment for depression for some individuals. Research is still needed in this area as there may be more deficiencies out there that are linked to depression.. ...Read more

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Is it true that excessive amounts of stress can lead to premature graying of the hair?

Is it true that excessive amounts of stress can lead to premature graying of the hair?

Premature Gray: Seeing photos of our presidents before and after their terms in office, you'd have to wonder about stress graying their hair. Still, science so far hasn't documented a direct relationship between stress and hair graying. Graying is usually genetically determined, along with multiple biochemical changes. Hair may be more likely to fall out with stress -- perhaps leaving more gray ones behind. ...Read more

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Can a lack of vitamins contribute to getting cancer?

Can a lack of vitamins contribute to getting cancer?

I don't believe it: Real vitamin deficiencies in the developed world are rare except in people on crackpot "health" diets, except vitamin d deficiency which is rampant. A full supplement should cost $10/year. The results of "diet and cancer" surveys, like most memory-based public health studies, turns up huge amounts of contradictory claims. Since vitamin deficiency doesn't mutate genes, i doubt any real cancer link. ...Read more

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Does a lack of sleep lead to anemia?

Does a lack of sleep lead to anemia?

No: Both lack of sleep and anemia can lead to feeling tired and fatigued. Anemia is caused by either blood loss, cell destruction or insufficient production. In women, iron deficiency anemia and excessive bleeding during menstruation are the most common causes. Lack of folate (folic acid) and vitamin B12 also cause a different form of anemia. There are also genetic diseases that result in anemia. ...Read more

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Can vitamin and protein deficiency be the cause of depression?

Can vitamin and protein deficiency be the cause of depression?

YES!!!: Depression can be a complex problem with many possible causes. Vitamin d deficiency (present during winter months in virtually everyone who does not take high doses of d) commonly causes depression. Deficiency of b12, folate & other b's can cause too. Deficiencies of the Amino Acid tryptophan causes low serotonin; low phenylalanine & tyrosine causes low dopamine. See a holistic doc for assessment! ...Read more

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Is there a vitamin or mineral deficiency that can cause problems with one's focus?

Is there a vitamin or mineral deficiency that can cause problems with one's focus?

Yes ...: When using nutrients, one has to be careful of not overloading the body. Elevated copper can increase hyperactivity, oxidative stress and stress zinc requirements. The wrong kind of folate (folic acid) for those with mthfr mutations can also affect mental wellness. If there is a specific condition you are treating it is best to do so under guidance. Also, add one supplement at a time to assess effects. ...Read more

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Can there be any cure for osteoporosis coupled with Paget's deasease of the bone?

Can there be any cure for osteoporosis coupled with Paget's deasease of the bone?

Yes: Paget's disease and osteoporosis are typically treated with the same type of meds called bisphosphonate. However, treatment for pagets requires a higher dosage and can send the disease into remission. ...Read more

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Some degree of gum recession can happen as people age. Can this also be the situation with bone loss without the presence of periodontal disease?

Some degree of gum recession can happen as people age. Can this also be the situation with bone loss without the presence of periodontal disease?

Bone loss: Bone loss is associated with gum loss, they go hand in hand. Most perio is due to bacteria (better hygiene) but can be increased by trauma, smoking, systemic disease, nastier bacteria, meds, etc. The biggest reason we get more loss with age (besides disease and inability to clean) is we have more time to be exposed to the above bad habits. I have seen 80 year olds with all their teeth. See a dds. ...Read more

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Can a brief history of anorexia nervosa lead to permanent changes in metabolism?

Can a brief history of anorexia nervosa lead to permanent changes in metabolism?

Not known for sure: I am thinking that there have not been enough studies on this issue although you use the term permanent and for the purposes of discussion is might be more illustrative to focus on long term. In that sense, the changes in lean body mass percentage and the recruitment of brown fat that is more likely in the context of anorexia would make long term changes in metabolism possible! stay safe! ...Read more

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Can the stress of being born cause infants to get strokes or clots?

Can the stress of being born cause infants to get strokes or clots?

Yes: About 1 in 4, 000 babies born will have a stroke around the time of birth, often related to the increased tendency towards clotting in the few days before and after birth in both mother and baby. While it's not exactly accurate to say "stress" causes stroke in newborns, birth trauma can be one of many possible causes. Heart or blood disorders, placental disorders, and infection are other causes. ...Read more

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What kind of conditions/deficiencies result in poor healing in tendons/ligaments , or suspectability to injury ?

What kind of conditions/deficiencies result in poor healing in tendons/ligaments , or suspectability to injury ?

Here's a few: Poor nutrition or use of steroids will lead to poor healing. Overexercise or stress to limbs and joints without proper preparation, such as strength training and appropriate warm up, can also lead to injury. Also, some chronic disease processes, such as diabetes, can make one susceptible to injury. Good luck. ...Read more

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Could a cure for progeria syndrome lead to the "fountain of youth"?

Could a cure for progeria syndrome lead to the "fountain of youth"?

Who knows???: First we need to understand the cure or Rx for progeria, then it can be tested to see if it has broader application. In the meantime, we know a lot about what shortens life: obesity, lack of exercise, smoking and complications of those like diabetes, heart disease, chronic lung disease, but most of us would rather have a pill than do the hard work it takes to stay fit. ...Read more

Hypocalcemia (Definition)

Hypocalcemia refers to low measured levels of calcium in the blood. Symptoms of hypocalcemia may include numbness/tinglng of he hands and mouth or cramping. In severe cases, one's ability to think may be impaired. Hypocalcemia may be due to poor diet, vit d deficiency, disorders of the parathryoid ...Read more


Dr. Linda DiMeglio
73 doctors shared insights

Brittle Bone Disease (Definition)

Typical brittle bone disease is due to loss of mineralization of normal bone and can be diagnosed by regular x-rays. It is uncommon in men , in which case other diseases and conditions may be suspected, such as malabsorption, or other systemic disease. In women, it ...Read more