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Doctor insights on: Can A Herpes Culture Test Be Wrong

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Is it possible for herpes culture and blood test to be wrong? I received negative for both...

Is it possible for herpes culture and blood test to be wrong? I received negative for both...

Not exactly: It is not so much the blood test is wrong, as it might be too early after infection to show up. Culture only positive if "catches" the organism to grow. There are a couple of types of herpes (hsv1/hsv2) as well. Usual to repeat blood work after 3-6 months if equivocal results. ...Read more

Dr. Krishna Kumar
24 Doctors shared insights

Herpes Culture (Definition)

A herpes culture is a test performed in a microbiology or virology lab, where they use a swab from a suspicious area and try to "grow out" the herpes virus. This kind of test is notoriously inacurate- and a negative viral culture should not be taken as proof that you don't have the herpes virus. It should be followed up with blood testing to confirm that you have not ...Read more


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If a herpes culture/test is negative, how accurate is that result?

If a herpes culture/test is negative, how accurate is that result?

Depends on timing: False negatives can occur, especially if the ulcer is cultured too late, after healing has already begun. False negatives are less likely to occur when the culture is taken from an intact vessicle (blister) that has been opened for the purpose of the culture, or from a very fresh ulcer. ...Read more

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Is it possible that a positive for a herpes culture be wrong?

Is it possible that a positive for a herpes culture be wrong?

Herpes culture: A positive culture means that the virus was present and actually grew and multiplied in the lab. The only way it would be wrong is if the made some kind of mistake with labeling your specimen and mixing it up with somebody else. That would be very very very rare for a culture. ...Read more

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Can herpes culture test be false positive? If so, now often?

Can herpes culture test be false positive? If so, now often?

Unlikely: A false positive result would be extremely unusual. It would require either laboratory contamination or a clerical or technician error in which the result was reported for the wrong patient. I trust herpes culture results. ...Read more

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Negative herpes culture and blood tests; pretty accurate?

Negative herpes culture and blood tests; pretty accurate?

Likely OK.: I don't know what your history is but if you had/have a herpes infection, you likely would have noticed skin lesions that could be irritating at some point in time. Many times there can be no symptoms but if you have this there would be some kind of outbreak at some point in time. The tests include tzank prep. Of scrapings that show giant cells, cultures are pos. In 48-96 h, elisa+pcr are great. ...Read more

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Is a herpes culture better than herpes blood test, or the other way around?

Is a herpes culture better than herpes blood test, or the other way around?

Molecular testing: Molecular testing for HSV has been approved by fda and is expected to be better than culture and antibody testing. ...Read more

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Is it possible to get a false positive herpes culture test? How often does it occur? What is the reasoning for it?

Is it possible to get a false positive herpes culture test? How often does it occur? What is the reasoning for it?

Rarely if ever: False positive results are very unlikely for HSV culture. If the test was actually a DNA test (PCR test), there is a slightly higher chance of false pos, but still very unlikely. If you have had a positive culture or PCR, for sure you have herpes at whatever site was tested (genital, oral). But if a blood antibody test, not culture or PCR, false positive results are quite common. Good luck. ...Read more

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If doctors swab for a herpes culture, does that mean its a serum test: the more reliable/updated test? What exactly does that mean?

If doctors swab for a herpes culture, does that mean its a serum test: the more reliable/updated test? What exactly does that mean?

Herpes test: The most accurate way to diagnose herpes is with a viral culture from a lesion. Serum tests for antibodies can be fraught with errors. ...Read more

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Tested negative for herpes culture test but have symptoms, any other test that I can take that is more accurate? I've had a sore for over 4 months

Tested negative for herpes culture test but have symptoms, any other test that I can take that is more accurate? I've had a sore for over 4 months

Sore: Most herpes sores would have resolved on their own by now, which suggests the sore may have a different cause. Consider a blood test for herpes (both HSV1 and HSV2), as well testing for syphilis (RPR), and other STIs like HIV and Hepatitis. Have a doctor examine the sore. ...Read more

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Boil on leg busted. More bumps appeared on genitals. 2 diff doctors say staph does not look like herpes. Culture shows herpes. Could this be wrong?

Boil on leg busted. More bumps appeared on genitals. 2 diff doctors say staph does not look like herpes. Culture shows herpes. Could this be wrong?

Follow science: It could be wrong but I would review the the culture. Bumps on genitals are more likely to be herpes. If the treatment for the virus cures the bumps then it is probably not bacterial. ...Read more

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Fungal infect or STD? 2 negative herpes culture tests. Jockitch cream cleared up 1st time. Still redness around male urethra and occas spots on shaft

Fungal infect or STD? 2 negative herpes culture tests. Jockitch cream cleared up 1st time. Still redness around male urethra and occas spots on shaft

Here are some...: Glad to hear your good response to Jack Itch cream. Since, such creams usually contain anti fungal agent with steroid and direct to suppress and rid skin fungal infection, which inflict warm and moist areas like external genitalia and groins - called tine cruris. For the rashes on penile opening and shaft, you may try the same cream and see if responding in 1 wk. If not, seek pro-evaluation. ...Read more

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Herpes culture accuracy?

Herpes simplex: Culture of clinical materials for the presence of this organism are very accurate. ...Read more

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How accurate are herpes culture results?

How accurate are herpes culture results?

Very, other tests.: I don't know what your history is but if you had/have a herpes infection, you likely would have noticed skin lesions that could be irritating at some point in time. Many times there can be no symptoms but if you have this there would be some kind of outbreak at some point in time. The tests include tzank prep. Of scrapings that show giant cells, cultures are pos. In 48-96 h, elisa+pcr are great. ...Read more

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What is the definition or description of: herpes culture?

A test for the virus: A herpes culture is a test performed in a microbiology or virology lab, where they use a swab from a suspicious area and try to "grow out" the herpes virus. This kind of test is notoriously inacurate- and a negative viral culture should not be taken as proof that you don't have the herpes virus. It should be followed up with blood testing to confirm that you have not been exposed to herpes. ...Read more

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Herpes culture result: equivocal result - what does it mean?

Herpes culture result: equivocal result - what does it mean?

Probably borderline.: Culture results are usually positive in 48-96 hrs. Elisa and PCR are just as sensitive or more than culture. Seroconversion can document primary infections. A tzanck prep. From lesion scrapings can help make a clinical diagnosis by showing multinucleated giant cells or inclusions by cytology. ...Read more

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False positive herpes culture; what is the chance of it?

Fairly Small: Not too likely as a culture is the actual organism itself that was cultured from the patient's lesion in question. Unless it is a mislabeled specimen in the lab as an example. ...Read more

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Would a herpes culture come back positive if you have hpv?

Would a herpes culture come back positive if you have hpv?

Depends: You could be infected with both germs. They are both transmitted sexually and some infected persons can carry several infections at the same time. Some are relatively asymptomatic for extended periods. ...Read more

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The doc says my herpes culture came back positive? But do I have to take preventive medicine?

No: However if you get frequent outbreaks you may want to consider taking medicines as a preventative strategy. ...Read more

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I am currently being treated for genital herpes, culture not back to confirm. I also have a rash on neck, feet, arms. Is this all herpes?

I am currently being treated for genital herpes, culture not back to confirm. I also have a rash on neck, feet, arms. Is this all herpes?

Unlikely: Herpes lesions are usually localized. What you may have is an allergic rash in response to medication or something else. Your treating physician should be able to investigate. ...Read more

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I did viral culture test for herpes with sores from a first outbreak in my MOUTH. Result: positive type 2! Can type be wrong or is really genital???

I did viral culture test for herpes with sores from a first outbreak in my MOUTH. Result: positive type 2! Can type be wrong or is really genital???

It's possible: Type 1 is more common in the mouth, and Type 2 is more common in the genital region. It is also not UNCOMMON to have it vice versa, it is possible. Follow up closely with your doctor for treatment and continue to practice safe sex techniques. ...Read more

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Which herpes test is more accurate, culture or blood?

Which herpes test is more accurate, culture or blood?

Culture: Finds the virus itself rather than antibodies. The test is more specific, but some folks may harbor the virus without it being culturable. ...Read more

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Is a culture test more accurate then a igg herpes test or should I do both?

Herpes: No; Cell culture or PCR test may give a false-negative result if the sores have begun healing or if you are recently infected. It takes several weeks for HSV antibodies to show up in the blood. PCR and cell culture tests show that you have been exposed to the virus at some point. Your doctor may choose to do both or neither based on the physical examination. ...Read more

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Culture came back negative for herpes, is it possible these are wrong?

Culture came back negative for herpes, is it possible these are wrong?

Possible: Testing in general is accurate, however there are always chances of false negative testing. This can vary from test to test, but generally describes the chance that a reported negative test result is actually positive. Re-testing can help decrease the chances of a false negative test. ...Read more

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Why do people say you shouldn't get tested for herpes what is wrong with the test?

Why do people say you shouldn't get tested for herpes what is wrong with the test?

I do not know: If concerned for std's, there is no problem getting tested. Genital herpes can have many "negative" connotations associated with it and cause a lot of stress and anxiety, so maybe some people say don't get tested? ...Read more

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I had herpes type 1 and 2 test which came negative. After 2 months I have itchy and mild testical pain. I'm worried any one please tell me what is wrong?

I had herpes type 1 and 2 test which came negative. After 2 months I have itchy and mild testical pain. I'm worried any one please tell me what is wrong?

Unrelated: The tests are likely unrelated to your symptoms. Take testicular pain seriously and get evaluated by your primary care doctor as soon as possible. ...Read more

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I have herpes like symptoms on my genitals. But type 1 and type 2 tests both came negative. Can it be wrong? What else can this disease be?

I have herpes like symptoms on my genitals. But type 1 and type 2 tests both came negative. Can it be wrong? What else can this disease be?

Behcet's, drug rxn: Beh├žet's disease or a drug eruption are both possibilities. You may benefit from a biopsy. Have a dermatologist or urologist evaluate! ...Read more

Herpes (Definition)

There are different types of herpes infections; herpes simplex infection of mouth (gingivostomatitis) and lips (labialis) are the most common. Others include genital herpes, and herpes zoster. Herpes infection could very mild to very dangerous depending on the type and location of the body affected. I ...Read more