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Doctor insights on: Calf Swelling Negative D Dimer Arthritis

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Dr. Thomas Namey
2,426 doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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Polycythemia vera verified by second opinion. + Crohn’s. Unilateral calf swelling. Unilateral superficial vein. D-dimer + US normal. Get venogram?

Polycythemia vera verified by second opinion. +  Crohn’s. Unilateral calf swelling. Unilateral superficial vein.

D-dimer + US normal. Get venogram?

Difficult to know: Polycythemia vera and Chrons are both risk factors for DVT . Also your sign and symptoms are suspicious for DVT. Venous Doppler US for a single exam may miss small DVT especially in the calf. D dimer if normal pretty sensitive. Many options repeat: Ultrasound and possibly d dimer, venogram [but these are not done much now], follow closely. Recommend close follow up with your doctor/ vein expert. ...Read more

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Random sharp pains in right calf. Neg d dimer and dopplers. What could this be? No swelling and touching doesnt hurt it. Just happens randomly

Random sharp pains in right calf. Neg d dimer and dopplers. What could this be? No swelling and touching doesnt hurt it. Just happens randomly

Be seen: A detailed exam and appropriate studies would likely determine the cause. Considerations can include abnormalities in the calf or back if the knee such as a bakers cyst or even a sciatica from the back; multiple other potential causes as well. ...Read more

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Left calf pain that comes and goes every few weeks. D Dimer was negative. Could I still have a clot possibly? No redness or swelling. Just pain.

Left calf pain that comes and goes every few weeks. D Dimer was negative. Could I still have a clot possibly? No redness or swelling. Just pain.

Clot unlikely: A negative D dimer test is good at excluding blood clots. It is not feasible to provide a meaningful opinion without taking additional history, physical examination and may be some tests. If the pain has lasted more than a couple of weeks, you should consult a doctor. ...Read more

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I am having calf pain that radiates from the top of my calf to the bottom. Maybe some swelling can't tell. Had d dimer done-negative. Could it be dvt?

Possibly : Although a neg d-dimer makes the likely hood of a DVT less likely it is possible. A duplex scan of the veins would diagnose a
dvt. There a lot of reasons for a leg pain like you describe. Arterial disease in a 21 y/o female would be very unlikely. ...Read more

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If I have Crohn's disease and polycythemia rubra vera is a negative venous us and d dimer good enough to rule out a clot? Have leg swelling lower leg

If I have Crohn's disease and polycythemia rubra vera is a negative venous us and d dimer good enough to rule out a clot? Have leg swelling lower leg

Nearly: The gold standard to definitively rule out an deep vein clot is venography. However, this is rarely if ever necessary given that compression ultrasonography has a sensitivity and specificity each of around 95% compared to venography. I would recommend further evaluation if you have had an injury in that leg or a previous DVT. Otherwise it is unlikely that you have a thrombus with a negative US. ...Read more

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I had a d dimer yesterday for leg pain no swelling came bk negative now im panicking i took 75mg aspirin 24 hours before test can this give false neg?

I had a d dimer yesterday for leg pain no swelling came bk negative now im panicking i took 75mg aspirin 24 hours before test can this give false neg?

The D dimer: test reveals products of a DISSOLVED clot and does not distinguish what DISSOLVED it! However although Aspirin can PREVENT CLOTTING it does NOT dissolve clots THUS UNLIKELY to produce a "false negative"
Hope this helps!
NOT TO WORRY!
Dr Z ...Read more

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My doc told me i had arthritis in my left leg. I have been having like 3 second hot flashes in my ankle.I had a negative d-dimer test.What could it be?

My doc told me i had arthritis in my left leg. I have been having like 3 second hot flashes in my ankle.I had a negative d-dimer test.What could it be?

Possible nerve: Irritation. Sometimes if a nerve is getting mildly irritated in a certain area, such as the peroneal nerve around the fibular head, you can have some heat like feeling transiently. Have you noticed any change in the way you walk prior to the burning? Any unusual pressure around areas prior to the burning? Where is the arthritis? If it is in the ankle, the inflammation can irritate small nerves too. ...Read more

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Swelling behind knee, slight numbness in lower leg and toes, d dimer neg for clot, told I have low prob for clots in er, what else could this be?

Swelling behind knee, slight numbness in lower leg and toes, d dimer neg for clot, told I have low prob for clots in er, what else could this be?

Baker's cyst: A baker's cyst can cause swelling in the back of the knee, and if large enough cause cause pain and numbness there and into the leg. See an orthopedist for evaluation. ...Read more

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Can I safely ignore unilateral calf pain (1 week+) with light bruising after normal D-Dimer or should I pursue an ultrasound? No heat or swelling.

Can I safely ignore unilateral calf pain (1 week+) with light bruising after normal D-Dimer or should I pursue an ultrasound? No heat or swelling.

NoRhymerForD-Dimer: What caused the pain? A strain or a contusion? Do you remember? A normal D-Dimer is reassuring, but no test is 100% accurate or test result 100% certain. There are certain risk factors I'm sure your doctor knows about (like smoking with birth control pills, certain blood clotting problems, etc etc). If that pain is still there in a week or so, especially if the calf swells, get it checked again! ...Read more

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Back of leg hurts for 2 weeks doctors say definantly not a blood clot cause d dimer was normal no swelling and is worst when resting?

Back of leg hurts for 2 weeks doctors say definantly not a blood clot cause d dimer was normal no swelling and is worst when resting?

Clot not likely: Since your doctor has evaluated you for a blood clot and found it to be unlikely by exam and testing, you are likely dealing with some other cause of calf pain like muscle strain, lumbar radiculopathy, or baker's cyst. ...Read more

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Elevated d dimer level, CT scan of lungs normal.Left chest/neck/shoulder pain. Leg slight swelling and painful twitches in legs(ultrasound normal)why?

Elevated d dimer level, CT scan of lungs normal.Left chest/neck/shoulder pain. Leg slight swelling and painful twitches in legs(ultrasound normal)why?

Need more informatio: We need more information on your laboratory finding, your clincial evlaaution, your examination. Your physicians were looking for blood clots, emboli. You need to discuss this with your physicians. ...Read more

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Does a hyperextended knee also lead to calf swelling?

Does a hyperextended knee also lead to calf swelling?

Yes, calf X's knee: The calf muscles cross the back of the knee as they originate from the back of the thigh bone next to the knee capsule. When the knee hyperextends, the back of the knee often over stretches. This can cause injury to your knee that includes the posterior capsule and juxtaposed calf muscles. The calf muscles can become strained or torn causing pain and swelling in the injured calf muscle. ...Read more

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Calf swelling--do I apply ice or heat?

Calf swelling--do I apply ice or heat?

Depends: Ice is good on acute injuries to decrease the inflammation, like when an athlete sprains an ankle. Heat promotes blood flow to the area in order to help healing. Depending on the cause of your calf swelling will dictate which would be more helpful. Many times if both calfs are swelling it can be from decreased venous return and therefore leg elevation, and compressive stockings can help. ...Read more

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I have RA can it cause mild calf swelling?

I have RA  can it cause mild calf swelling?

Yes: This can also have many other causes. It can be a side effect of medications, related to a bakers cyst of the knee or something very serious like a blood clot. You should see your doctor and get a definite diagnosis. ...Read more

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Can dystonia cause calf swelling?

Can dystonia cause calf swelling?

Dystonia: It can cause muscle to contract and appear like swelling, but usually it is not swelling from dependency of fluid as usually cause of swelling of legs. ...Read more

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Why did I get thigh/calf swelling out of nowhere?

See your doctor soon: One of the worst things we worry about with one-sided calf or leg swelling out of the blue is a blood clot. If you haven't had any trauma recently or think you've pulled a muscle, you should see your doctor. Other things include a ruptured baker's cyst (a fluid filled sac behind the knee), or a ruptured head of one of the calf muscles. Best of luck and take care. ...Read more

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Calf swelling and pain. Home treatments?

Calf swelling and pain. Home treatments?

No DVT?: The first thing to make sure that you don't have is a dvt. Once you are seen by a doctor and know you don't have a dvt, taking anti-inflammatory medicines, using ice, and resting the sore calf should help make you better. ...Read more

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I am experiencing leg pain, leg swelling and calf swelling my leg is red hot to touch my gp is not open don't know what to do ?

I am experiencing  leg pain, leg swelling and calf swelling my leg is red hot to touch my gp is not open don't know what to do ?

Usually an emergency: Calf-swelling with pain is usually an emergency because doctors want to evaluate the patient to see if there is a blood clot in the leg. Such a clot can break off a chunk, flow to the lungs, and be fatal. There are other causes of leg pain and swelling, but always rule out the potentially lethal ones first. One should tell doctors about any surgeries, injuries, medications, prolonged sitting, etc. ...Read more

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I have a intra muscular calf contusion from impact to the calf. Swelling pain limping no bruising. Can walking on it do more damage. I have noinsurane?

I have a intra muscular calf contusion from impact to the calf. Swelling pain limping no bruising. Can walking on it do more damage. I have noinsurane?

No health insurance: Just because you don't have insurance doesn't mean you can't get healthcare. On my website (sorry, no way around that), i've listed a number of options for free (or at least low cost) health care, drugs ; tests. Or skip my site ; just search online for free healthcare. Lots of options are available to you. Walking won't make bruise worse. But do go see a doc if pain gets worse rather than better. ...Read more

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What does it mean if I have calf swelling?

What does it mean if I have calf swelling?

Depends needs exam: You could have something as simple as a muscle contusion,
but you need to be checked for possible signs of phlebitis or
circulation problems. If there is trauma it is probably less serious. But a warm swollen calf without injury could be indicative of a clot and needs immediate treatment. ...Read more

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What is the definition or description of: calf swelling?

What is the definition or description of: calf swelling?

Enlarged lower leg: I assume we are talking about a baby cow...
The area of which you are referring to, are the 2 muscles that make up the posterior of the lower leg. The larger gastocnemious muscle and the smaller soleus muscle together are referred to as the calf muscle. Swelling could be due to trauma or any number of origins. They attach to the achilles heel tendon. ...Read more

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Achy dull ache in right calf, swelling at FRONT of leg with a sticking out vein, don't think its serious as no swelling in calf, protein s Defiency.

Achy dull ache in right calf, swelling at FRONT of leg with a sticking out vein, don't think its serious as no swelling in calf, protein s Defiency.

Smell trouble: You have Vitamin C def therefore you are at risk for blood clot, I would suggest you see a doctor to evaluate this even if it doesn't bother you much, it's very wise to rule out a blood clot with Doppler Ultrasound. ...Read more

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Legs ache and feel heavy - 2 months. It's affecting my whole life. Now I have a painful calf swelling - what is it? Only been given painkillers :(

Legs ache and feel heavy - 2 months. It's affecting my whole life. Now I have a painful calf swelling - what is it? Only been given painkillers :(

Need more evaluation: Being so young these symptoms would not be so common. There are several conditions that can cause these symptoms ranging from vascular causes to hormone imbalances. Pain killers are the last thing you should be on. You need a diagnosis. Seek out a second opinion if your pcp is only throwing pain meds at the problem. ...Read more

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I am experiencing calf pain and calf swelling. The following also describe me: Lower leg pain and Leg tenderness. What should I do?

I am experiencing  calf pain and calf swelling. The following also describe me: Lower leg pain and Leg tenderness. What should I do?

Why RU waiting?: Calf pain and swelling are at least two of the ingredients describing the possibility of a blood clot or blood vessel inflammation in the leg. I would not wait for the third. Failure to not treat a clot could be catastrophic. To remove all doubt, get ton urgent care ASAP. ...Read more

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Can a plantars wart (on the bottom, outside part of the foot) cause foot, ankle and calf swelling and pain? Or is it likely 2 separate issues?

Not directly related: These are likely separate issues. A plantar wart can create pain, resulting in a change in your gait (how you walk) and thus put more pressure on other areas of your leg. Thus, it's theoretically possible these two issues are INDIRECTLY related. However, foot/ankle/calf swelling and pain without an injury make me think about a potential blood clot. Please seek help from a physician if persistent. ...Read more

Calf Swelling (Definition)

I assume we are talking about a baby cow... The area of which you are referring to, are the 2 muscles that make up the posterior of the lower leg. The larger gastocnemious muscle and the smaller soleus muscle together are referred to as the calf muscle. Swelling could be due to trauma or any number of origins. They attach to ...Read more


D Dimer (Definition)

D-diner is a breakdown product from blood clots. It can be found elevated in certain conditions like pulmonary embolus (blood clot which travels to the lung) deep venous thrombosis (blood clot in deep vein of legs usually) and disseminated intravascular coagulation (diffuse clot formation from severe infection which ...Read more