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Doctor insights on: Calcineurin Inhibitor Medicines

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I heard that calcineurin inhibitors are not safe for eczema treatment. Is this true?

I heard that calcineurin inhibitors are not safe for eczema treatment. Is this true?

Use properly: Recently (1/2006) the fda placed a “black box” warning on these drugs. Both the american academy of allergy, asthma and immunology and the american academy of dermatology feel that this was an unfortunate and unnecessary decision, as these drugs are very safe when used properly. ...Read more

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Dr. Lawrence Kessler
23 doctors shared insights

Calcineurin Inhibitor (Definition)

Topical calcineurin inhibitors are second line treatments for eczema, when ...Read more


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Prostate is enlarged again with inhomogenous echotexture even while taking 5-alpha-reductase inhibitors medicines .. is this very dangerous sign ?

Prostate is enlarged again with inhomogenous echotexture even while taking  5-alpha-reductase inhibitors medicines .. is this very dangerous sign ?

See remark: Are you talking about your husband? young lady ? the medicine taken is to SHRINK the size of prostate If there is irregularity in texture of prostate, consult with a urologist .He must not be old if you're 28 yrs. The medicine taken MAY cause changes in prostate Relax ,Tumor is not common in middle age men specially from your part of the world.Best regards ...Read more

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In 2011 i was in a study(gs-us-248-0120 ) for hep c. Drugs were tegobuvir, gs5885, gs9451 & ribo. I failed week 2. Am i now resistant to inhibitors?

In 2011 i was in a study(gs-us-248-0120 ) for hep c. Drugs were tegobuvir, gs5885, gs9451 & ribo. I failed week 2. Am i now resistant to inhibitors?

Probably not: I would certainly get evaluated again by a gastroenterologist, and hopefully start with the new medication combination of sovaldi, Ribavirin and peg-interferon for 12 weeks. >90% "cure" rate. ...Read more

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Is there HIV drug resistance to protease inhibitors?

Is there HIV drug resistance to protease inhibitors?

Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more

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What is an ACE inhibitor/medicine?

What is an ACE inhibitor/medicine?

Blood Pressure Treat: Ace inhibitors block the conversion angiotensin i to angiotensin ii, which constricts the vessels, increases the following: salt retention in the kidney, sympathetic tone, aldosterone and ADH (vasopressin) (anti-diuretic hormone) secretion. The inhibition of this conversion decreases blood pressure and wall stress in the heart muscle. ...Read more

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How could a drug inhibitor be useful in treating cancer?

How could a drug inhibitor be useful in treating cancer?

Need more clarity: Please be more specific...which drug and what inhibitor are you asking about???? tell us what exactly is in your mind.Right now it is not clear to me! ...Read more

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Hello What is the best medicine (proton inhibitor) to take for GERD.Thanks?

Hello What is the best medicine (proton inhibitor) to take for GERD.Thanks?

Nexium (esomeprazole) is: probably the strongest second generation PPI and I would recommend it. It is OTC but prescription may be cheaper. ...Read more

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Can you tell me about drugs called renin inhibitors are used to treat hypertension. explain how they would have this effect.?

Can you tell me about drugs called renin inhibitors are used to treat hypertension. explain how they would have this effect.?

See below: Here's everything you always wanted to know but were afraid to ask: http://www.us.elsevierhealth.com/media/us/samplechapters/9780723431855/9780723431855.pdf ...Read more

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Have any undesirable effects been seen in long term use of the blood pressure drugs of the ACE inhibitor class?

Have any undesirable effects been seen in long term use of the blood pressure drugs of the ACE inhibitor class?

Same as short-term: Analyses have not shown any clear risks, including with regards to risk of cancer. Risks over long-term appear to mimic that seen in short-term use (e.g. Risk of hi potassium, kidney function abnormalities); sometimes this can show up after years on the medicine. There may even be benefits to chronic use (apart from intended benefits), such as lower risk of diabetes or atrial fibrillation. ...Read more

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Does dopamite(dopamine supplement) increase more dopamine level or prescribed medicine like biperiden(dopamine reuptake inhibitor) does?

Does dopamite(dopamine supplement) increase more dopamine level or prescribed medicine like biperiden(dopamine reuptake inhibitor) does?

I'm curious: Why do you believe you need to take medication that claims to affect dopamine, especially OTC remedy which will NOT cross the brain-blood barrier? If you are depressed, you could see a psychiatrist, and if you have Parkinson's disease, a neurologist. ...Read more