Doctor insights on:
Cah Panel 9
Hepatitis?: Is that chronic active hepatitis you are referring to? If it is, no, that is an adult disease. However your child can have some form of hepatitis, of which there are quite a few types. As usual, this is a question for your pediatrician, and parents history is very important with relation to a child's health, too. ...Read more
Not always: Unless it's onset is with birth and associated with severe salt wasting (that's why it's part of the newborn screen in all 50 states). It's carrier rate is quite common however, almost 1 in 40 so many people ate walking around without knowing they are carriers! ...Read moreSee 1 more doctor answer
Does late onset cah cause older females to get masculanization (because of proliferation of androgens) features such beard, etc.?
Does glycyrrhizic acid (in liquorice root) have glucocorticoid effects? If so, has it ever been studied for use in treating lo-cah? Study links?
No: Glycyrrhizinic acid inhibits an enzyme in the kidney (11? -hydroxysteroid dehydrogenase). This enzyme inactivates cortisol in the kidney. Inhibition of this enzyme leads to decreased inactivation of cortisol and thus to increased cortisol levels. Not expected to work in cah since this is characterized by an inabilty to make cortisol. ...Read more
Non classical CAH: Non classical congenital adrenal hyperplasia is diagnosed via a single blood test, drawn in the morning and looking at adrenal steroid levels (17-hydroxyprogesterone, androstenedione and testosterone). This may be sufficient to make the diagnosis of CAH. An ACTH stimulation test is done to confirm the diagnosis. Needs follow up with an endocrinologist. ...Read more
2 distinct diseases: These are 2 very different conditions, both of which result in inadequate production of cortisol (as well as mineralocorticoids). Addison disease = failure of or destruction of the adrenal cortex. Cah = enzymatic deficiency which blocks the hormone production in the adrenals, generally presenting as a newborn. Similar results--potentially lethal cortisol deficiency--but very different diseases. ...Read more
Why the contradiction between dr belilovsky nd dr khanna's answers to same question? "can one have both of these diseases addison's and late onset cah
CAH is: Not adrenal insufficiency as addison';s disease is. While there are various forms of cah due to different genetic abnormalities and hormone alterations. Most of these conditions involve excessive or deficient production of sex steroids and can alter development of primary or secondary sex characteristics in some affected infants, children, or adults. ...Read more
?: Not sure, this is not a clear question, please clarify. ...Read more
What is CAH?: Please write your question again without using abbreviations. Thanks. ...Read more
Yes: If there is a high index of suspicion for any disease, test for that disease. Most diagnoses are made by a bright, experienced, knowledgable mind. Most testing corroborates that diagnosis. ...Read more
I was dx'd with CAH 34 years ago. Now I have high cortisol (28) lowered acth (11.2) and almost 0 aldosterone (<1.0). Is this typical of CAH?
Yes: Depending on the type you have, it could be - most commonly the cortisol level is low and there is an elevation of mineralocorticoids like aldosterone. Since there are at least 4 distinct types of CAH, I'd need more information to answer your question. The best way to personally address your questions is to sit down with your endocrinologist and ask for an update on your condition... ...Read moreSee 1 more doctor answer
OldDiseaseOld Info: Congenital Adrenal Hyperplasia is an old disease in which there is congenital deficiency of an enzyme which is needed in synthesis of Cortisol and also Aldosterone and is treated with the replacement with these hormones and there is nothing new ...Read moreSee 1 more doctor answer