Doctor insights on:
Ca 15 3
Pandora Box: Test. You open it and you derive no useful information. It was meant to be a tet forearly detectionor recurrence, but it is not trustworthy, whether normal or abnormal. Ordering it is well intentioned (perhaps) but not recommended by any established guideline, and causes concern and testing that is expensive. ...Read more
My ca 15-3 is 2.3 level higher and my ca 12-5 is 3.8 higher than the normal lvl. What does this mean?
Why you did the test: My first question will be why did you have the tests done in the first place? Tumor markers like ca 15-3, ca 125- are not supposed to be done as a screening test. They are not reliable & very non specific/not sensitive. They are mainly done to certain cancer patients to follow up their response to therapy given for their cancers. It could be infection, inflammation, ca etc. D/w your md in detail. ...Read more
Tumor/ inflammation: These are not ideal biomarkers because they are not specific for cancer. CEA of Gold first thought to be good cancer marker elevated if one smokes or takes an enema. CA 15.3 elevated in some ovarian cancers but also in cirrhosis of the liver. Neither define a specific immunogenic tumor protein .and should not used for diagnosis of cancer Best used for monitoring. ...Read more
In a nutshell:: No. These are not screening tests for the normal population. Only in select patients with humongously increased risk like certain mutation carriers or people with very strong family history these markers may be considered and even then there are no data to my knowledge that shows it decreases chances of dying of cancer. Talk to your doc about age and risk appropriate screening tests for you. ...Read moreSee 2 more doctor answers
I did a ca 15-3 test and the result is 45 u/ml. Did the same test in 2007 and result was 33 u/ml. Why?
Need work up: Tumor marker 15-3 is used to monitor ( normal 30 u )progression of breast cancer. Some time for screening in which only 30% positive , if it is done on you for that , need work up, beside mammogram may need MRI of breast, possible biopsy of suspicious lesions .High levels are also found benign conditions , inflammation, lactation, pregnancy etc see your doctor. ...Read more
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