Doctor insights on:
Ca 125 Over 1400
Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?
Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read moreSee 1 more doctor answer
Ca125 is also known as Cancer antigen 125. Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more
Not necessarily.: The ca125 tumor marker is a notoriously non-specific indicator of disease (i.e. It can be elevated for reasons other than cancer). It is frequently most useful for tracking the progression or regression of a disease over time and less useful as a standalone diagnostic test. ...Read moreSee 1 more doctor answer
Should i go right to the cancer specialists? Abdominal pain started monday 4/2, with low grade fever (100.2), nausea and tiredness. I have an ovarian cyst 4cm, non-fluid filled. Awaiting ca-125. Pain and nausea has worsened significantly over the weekend.
Hopefully : Hopefully you got guidance from the gyn np. By the way, it is always good regardless of one's health and age to prepare your estate and will. I would not jump to a cancer diagnosis until you learn more. Fever is not typical of ovarian cancer. You may need surgery to get a clear answer however. Take care, i hope all is well. ...Read moreSee 1 more doctor answer
Ovarian Cancer: It is a tumor marker for ovarian, endometrium, fallopian tube, lung, breast and gastrointestinal tract cancers. It is commonly used to follow ovarian cancer in response to therapeutic treatments and can be positive in nearly 80% of cases. It is not specific to cancer, however, and can be elevated in benign abdominal problems too such as endometriosis. ...Read moreSee 1 more doctor answer
CA-125: Cancer antigen 125 (ca-125) is a protein found on the surface of many ovarian cancer cells. It also can be found in other cancers and in small amounts in normal tissue. A ca-125 test measures the amount of this protein in the blood and can be used as a tumor marker. ...Read moreSee 1 more doctor answer
Ca 125: The "normal" ca125 was established for post-menopausal women at <35 (any value 0-35). Most premenopausal women will also have values in this range but not always since there are many benign reasons it can fluctuate. Some "healthy" women of all ages will have a level above 35! this is one of the reasons it is not effective as a screening test. ...Read moreSee 1 more doctor answer
CA-125: This marker is elevated significantly at this value. It's greatest specificity for ovarian cancer is in post-menopausal women, but a variety of things that irritate the lining of the abdomen and even chest, can elevate it mildly. So things like appendicitis, endometriosis, and even diverticulosis can also result in high levels. But, getting checked out for what is behind this is a good idea. ...Read more
Yes: Ca 125 is not a good screening test. See this site for more info. http://www.medicinenet.com/ca_125/article.htm. ...Read more
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