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Doctor insights on: Ca 125

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What causes my ca 125 to go up?

What causes my ca 125 to go up?

Many causes: It is commonly elevated in ovarian cancer. But it can go up from any reason which causes irritation of the peritoneal lining of your abdomen which includes some benign conditions too. It depends on the level and also if it is going up steadily or staying elevated but stable and not increasing. Your gynecologist can help you to sort it out. ...Read more

Dr. Al Hegab
128 doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


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My doc didnt say anything abt biopsy/surgery nodule/cyst 2cm hv hypothyroidism taking 25 of levo he say 2nd ultrasound in 8 mon do I hv cancerous nod?

My doc didnt say anything abt biopsy/surgery nodule/cyst 2cm hv hypothyroidism taking 25 of levo he say  2nd ultrasound in 8 mon do I hv cancerous nod?

Good questions: B"sd back again! 90% + of thyroid nodules are not cancer. Also , thyroid cancers grow slowly and rarely spread until they are 4 cm or more. If a nodule does not grow over time time it is not likely to be cancer. It is fine to keep a close watch on a nodule and not do a biopsy right away. Most endocrinologists do their own US and can offer you a biopsy on the spot if that seems best for you ...Read more

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What happens if ca 125 is normal .am I free from cancer?

I wish: CA 125 is elevated in some, but by no means all, ovarian cancers, and in enough healthy people to make it not very helpful as a screening test. It's also normal in the vast majority of people with cancer elsewhere. ...Read more

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Vomiting 6/w after anything I eat/drink. docs don't know what's wrong yet. Hard to swallow, tired, thirst, I don't want to eat/drink I'll throw up?

Vomiting 6/w after anything I eat/drink. docs don't know what's wrong yet. Hard to swallow, tired, thirst, I don't want to eat/drink I'll throw up?

If your doctor: cannot figure out, it would be impossible here. Go back to your doctor, so he/she can figure it out for you. ...Read more

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I squeeze my nipple hard & I see white stuff commin out && it's clear && I look it up online it saying it's normal & I shouldn't have to worry . & no im not pregnant . I'm just very curious .. ?

I squeeze my nipple hard & I see white stuff commin out && it's clear && I look it up online it saying it's normal & I shouldn't have to worry . & no im not pregnant . I'm just very curious .. 
?

Nipple Discharge: Nipple discharge is the one of the most common breast complaints, and it usually benign. Benign nipple discharge is usually bilateral, and occurs with breast manipulation vs suspicious discharge which is spontaneous, bloody, unilateral, associated with a breast mass, and in women over 40. Your doctor will need a thorough history and physical exam if you are not breastfeeding. ...Read more

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I was wondering what does testicular cancer look & feel like?

I was wondering what does testicular cancer look & feel like?

Lump: It's a new mass attached to the testis, often with an irregular surface. It's usually not painful. ...Read more

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Found a kidney bean size lump to off breast near armpit what cud it b, doesn't hurt unless i rub it?

Found a kidney bean size lump to off breast near armpit what cud it b, doesn't hurt unless i rub it?

Lymph node: This lump is most likely a benign lymph node in/near armpit. Lymph nodes can enlarge and then shrink in response to infection/inflammation. If it does not shrink (or continues to enlarge) within 4 weeks, have your physician evaluate it. Most likely it's benign however. ...Read more

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Tonsil cancer fear, how do I find out if I have it?

Tonsil cancer fear, how do I find out if I have it?

Oral exam: The tonsils if not removed are easily recognized on oral examination. As one gets older then usually regress and are difficult to see- that is posterior and lateral to the tongue. If any question of pathology noted by your physician, a simple biopsy is used. Radiation virtually cures tonsil cancer. ...Read more

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I accidentally burned myself it's really small & now it's alil bubble am i suppose to pop it ?

I accidentally burned myself it's really small & now it's alil bubble am i suppose to pop it ?

No: The skin over the blister is protecting the skin underneath from a secondary infection. Leave it alone. It will eventually pop or go down on it's own. ...Read more

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I am having 8.7 cm overian cyst.I am 30.CA 125 result 45.7.I am from India.Doctor saying to do laparoscopy.I am scared.Is it necessary to do surgery ?

Yes: The size of the ovarian cyst is not suppressible with oral contraceptive pills, and the elevated CA 125 is a concern for a more serious problem.(cancer). CA 125's are notoriously mon specific and unreliable to predict cancer, but the laparoscopy will allow a ovarian assessment and biopsy to definitively determine the problem. ...Read more

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Hard thumps under skin? Various places. Told doc, she didn't know. Can't see it, but feel hard thumps. I do have ear infection n sinus won't drain.

Hard thumps under skin? Various places. Told doc, she didn't know. Can't see it, but feel hard thumps. I do have ear infection n sinus won't drain.

Lymph nodes maybe: lymph nodes generally get bigger when u get sick. sometimes they can hurt but usually they don't. if u r feeling them along your neck, that's probably just from your sinus & ear infection. they should shrink back down when you get better. if you have lumps in other places or if they are big, you should have them checked out because that could be more serious problem ...Read more

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Why would i.Be puking. N that it?

Why would i.Be puking. N that it?

Food poisoning: If all you have is sudden onset nausea/vomiting with no other symptoms, the likely answer would be food poisoning. Try and keep hydrated. If it persists for more than a day, i would definitely see a doctor. ...Read more

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Hv farsightednes using specs for -1.25 left n -1 fr ryt... Soft lenses doesnt suit... Cn i get operated?

Hv farsightednes using specs for -1.25 left n -1 fr ryt... Soft lenses doesnt suit... Cn i get operated?

Likely: Those numbers indicate mild nearsightedness. This is easily corrected with the laser. At 19 years old, you may not yet have a stable refraction. See a lasik surgeon in your area and discuss with him/her. ...Read more

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35wk n 5 pregnant n my dr said i loss my mucus plug n i was 2cm soft? N my cervix were really soft n my baby's heads already in position? Mean?

35wk n 5  pregnant n my dr said i loss my mucus plug n i was 2cm soft? N my cervix were really soft n my baby's heads already in position? Mean?

See details: You used a lot of question marks without actually asking a question. You should be able to feel it when the baby's head drops into position. This can occur as early as 32-34 weeks but it does not necessarily mean you will deliver early. It usually engages at 37-38 weeks. ...Read more

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My throat hurts when I swallow. Do I need barium swallow X-ray test?

My throat hurts when I swallow. Do I need barium swallow X-ray test?

See Your Doctor: Before any tests, you should see your doctor and determine what needs done. ...Read more

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A quarter sized hard mass was found on my right kidney tuesday .....What will happen to me ? I'm scared now

A quarter sized hard mass was found on my right kidney tuesday .....What will happen to me ? I'm scared now

Workup: How was this mass found? If a solid mass is found on a kidney it is usually assumed to be a cancer and is surgically removed. If the mass was seen on ultrasound you will probably get a ct with and without contrast. You will likely be referred to a urologist and assessed for surgery. If the mass is a primary renal cancer and is around 2cm, chances of a cure are good. ...Read more

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Have numb chin off n on few day n pin n needle feeling , do done blance test , n few other, told me its NT tumor , so doing neck n head MRI is tumor?

Have numb chin off n on few day n pin n needle feeling , do done blance test , n few other, told me its NT tumor ,  so doing neck n head MRI is tumor?

Chin numbness : The causes of chin numbness are variable. Anything that leads to inflammation or irritation of the inferior alveolar and mental nerve branches will cause chin numbness. Dental evaluation is a reasonable approach in addition to a medical evaluation. ...Read more

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I find it difficult 2 passout urea n i find it difficult to fart atimes n my left part of my abdonen n down my abdomen hurts?

I find it difficult 2 passout urea n i find it difficult to fart atimes n my left part of my abdonen n down my abdomen hurts?

See doc ASAP: We don't know enough about you to give you a definitive response. But pain is not normal. When associated with other symptoms, a visit to your pcp is in order as obstruction is a serious concern. S/he will know your history, meds , vital signs, etc. And be able to prescribe appropriate tests to achieve diagnosis. Good luck! ...Read more

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Sum1 help im extremly cold can't stop shakn can't swallow cuz it hurts 2 much im weak n achy n myhead throbs everytime i move n i jus threw up help?

Sum1 help im extremly cold can't stop shakn can't swallow cuz it hurts 2 much im weak n achy n myhead throbs everytime i move n i jus threw up help?

Chills, n/v: These are signs you are sick. Do you have a fever. You might need to see a doctor to be evaluated. This is clearly not normal. Headaches can be from many causes. Sounds like you are sick. Throat pain can be from strep throat, the doctor can do a simple test for this. ...Read more